VP/SVP, Global Development Leader

Nurix; Brisbane (CA); On-site; USD 350,000 - 700,000; Full time

Job summary

Nurix Therapeutics seeks a Vice President / Senior Vice President, Global Development Leader to provide strategic and tactical medical leadership across clinical development programs from phase 1 through launch. You will ensure safety, regulatory compliance, and alignment with corporate goals while coordinating Clinical Operations, Medical Monitoring, and Regulatory teams.

The role requires MD board certification in hematology/oncology, at least 10 years of clinical trial experience, and a

Qualifications

• MD, board certified preferably in hematology/oncology.
• Requires at least 10 years’ clinical trial experience in pharmaceutical industry with involvement in design or execution, including Ph3 planning.
• Clinical research experience in academic settings will be reviewed in light of development experience.
• Excellent communicator with proven leadership and cross-functional interaction.
• Able to lead in a fast-paced small company with shifting priorities.

Responsibilities

• Lead one or more program teams from phase 1 through launch, serve as single point of accountability for BTK Program GDT.
• As a member of the Clinical Executive Management Team, align portfolio goals with corporate strategy.
• Drive development plans, communicate plans, and ensure governance approvals.
• Facilitate cross-functional alignment among clinical, regulatory, operations, quality, and commercial partners.
• Identify risks and mitigation plans for technical and program challenges.
• Develop or refine the Clinical Development Plan and supervise clinical leads on protocols.
• Provide medical oversight for ongoing trials and review safety and activity data.
• Oversee CROs and internal staff in execution of therapeutic programs.
• Offer medical input to regulatory discussions (INDs, NDAs/MAAs) and training to clinical staff.
• Engage investigators and thought leaders to advance trials and share findings.
• Refine processes and methods for trial design, data collection, and final reports.
• Present data to executives and external medical colleagues in various settings.

Skills

Leadership

Clinical trial leadership

Cross-functional collaboration

Regulatory affairs

Strategic planning

Education

MD, board certified in hematology/oncology

Job description

Vice President / Senior Vice President, Global Development Leader (Bexobrutideg)

Nurix Therapeutics is a clinical stage biopharmaceutical company focused on the discovery, development, and commercialization of targeted protein degradation medicines, the next frontier in innovative drug design aimed at improving treatment options for patients with cancer and inflammatory diseases. Powered by a fully AI-integrated discovery engine capable of tackling any protein class, and coupled with unparalleled ligase expertise, Nurix’s dedicated team has built a formidable advantage in translating the science of targeted protein degradation into clinical advancements. Nurix aims to establish degrader-based treatments at the forefront of patient care, writing medicine’s next chapter with a new script to outmatch disease.

We are seeking a brilliant, organized and highly motivated leader who will provide strategic and tactical medical leadership and will deliver key clinical and scientific leadership to clinical development programs while ensuring the highest standard for safety and compliance with regulatory requirements and standard procedures. The ideal candidate should have experience working in a fast-paced dynamic environment. The successful candidate will report to the Chief Medical Officer. The responsibilities of this leader are listed below.

• Lead one or more Program teams comprised of functional representatives fromClinical Development(Clinical Operations, Medical Monitoring, Clinical Science),Research andTranslational Medicine, Regulatory, Technical Operations, Quality, and Commercial fromphase 1throughphase 3 and throughapproval and launch;serveas the single point of accountability for the BTK ProgramGlobal Development Team (GDT), and to create and drive key program decisions through appropriate governance forums, where appropriate
• As a member of theClinicalExecutiveManagement Team, partner with stakeholders to set clear direction and executeagainst goals for a portfolio of clinical stage therapies, ensuring the development and execution of program strategy is in line with corporate strategy and goals
• Drive the development and communication of program plans and development plan in partnership with the asset teams and program management
• Facilitate cross-functional communication; drive strategic and operational alignment with the Program team, functional leads, and Executive Management Team
• Identifychallenges and risks and prepare the team with mitigations to navigate through technical and program challenges as they arise
• Develop orparticipatein the refinement/update of the Clinical Development Plan (CDP);act asor overseethe clinical leadsfor protocols and supportive activities to meet the CDP objectives
• Provide medical oversight for ongoing clinical trials including regular review of clinical data to improve understanding of the molecule profile, including but not limited to safety and activity
• Provide clinical oversight for Company operational staff and contract research organizations (CROs) in all areas related to the execution of therapeutic programs
• Provideand or overseetraining and ongoing input to all members of the clinical team on medical and scientific issues related to theappropriate therapeuticfield
• Provide medical support for all relevant regulatory discussions and activities, such as IND’s and NDA/MAAs
• Interact with principal investigators and opinion leaders tofacilitateclinical trials research
• Refine and orestablishprocesses andmethods for design and implementation of applicable clinical protocols, data collectionsystemsand final reports
• Data presentation to executive leaders, internal and external medical colleagues in one on one or large group settings (50+).

Required Qualifications

• MD, board certified preferably inhematology/oncology
• Requires at least 10 years’ clinical trial experience in the setting ofpharmaceuticalindustry withdemonstratedexperience and involvement in clinical trial design or execution.In particular,Ph3clinical trial planning and execution.
• Relevant clinical research experience in academic settings will be reviewedin light ofclinical development experience
• Excellent communicator with proven leadership skills and the ability to interact in a cross functional environment
• Comfortable in a fast-paced small company environment with minimal direction and able to adjust workload based upon changing priorities
• Proven leadership experience leading high performing teams and individuals
• Hands on leadershipapproachwill be best suited for this critical role
• Experience working in a highly productive and high achieving collaboration

Fit with Nurix Culture and Values

• Strong teamorientation; highly collaborative
• Solutions and results-oriented focus
• Hands-on approach; resourceful and open to diverse points of view