VP, Clinical Development

Rigel Pharmaceutical, Inc.; United States; Hybrid; USD 336,000 - 405,000; Full time

Job summary

Rigel Pharmaceuticals, Inc. is looking for a Vice President of Clinical Development to provide executive leadership for experimental therapeutic programs.

Reporting to the CMO, you will shape clinical strategy, oversee trial design and execution, and ensure data integrity and regulatory readiness across multiple programs. This role requires collaboration with Biometrics, Clinical Operations, Regulatory Affairs and Drug Safety, with on-site presence at the South San Francisco headquarters on

Qualifications

• MD degree and advanced knowledge in hematology/oncology.
• Board certification in hematology or oncology preferred.
• Minimum 8 years in clinical research or drug development (Phase 1–4).
• Experience with global Health Authorities and regulatory strategy.
• Strong communication of complex data to inform decisions.
• GCP knowledge and clinical trial design expertise.

Responsibilities

• Provide executive oversight for design, planning and execution of clinical development programs.
• Lead development and implementation of clinical development plans aligned with product strategy and lifecycle objectives.
• Ensure high-quality trial execution, data collection and reporting per GCP and standards.
• Oversee key clinical documents: protocols, IBs, study reports and regulatory materials.
• Serve on cross-functional project teams and governance bodies.
• Collaborate with Clinical Operations and CROs for efficient trial execution and safety monitoring.

Skills

Executive leadership

Strategic thinking

Cross-functional collaboration

Excellent communication

Education

MD degree in hematology/oncology

Board certification in hematology or oncology

Job description

POSITION SUMMARY

Reporting to the Chief Medical Officer (CMO), the Vice President Clinical Development provides executive leadership for the company's clinical research and development activities within designated therapeutic areas and/or programs. The Vice President is responsible for the strategic planning, execution and oversight of clinical trials and related data generation activities in support of Rigel's product development and regulatory objectives. The Vice President Clinical Development serves as a senior leader within Clinical Development, accountable for clinical trial execution, data integrity, regulatory readiness and cross-functional alignment. The role partners closely with Biometrics, Clinical Operations, Regulatory Affairs, Medical Affairs and Drug Safety to ensure clinical programs are executed in accordance with corporate strategy, regulatory requirements and medical standards. The Vice President Clinical Development contributes to portfolio-level decision making and represents Clinical Development in internal governance forums and selected external engagements. Employees designated as onsite or hybrid are expected to be onsite at Rigel's South San Francisco headquarters during business hours on Wednesdays and Thursdays each week. Employees designated as remote are not subject to the weekly onsite requirement but are expected to be onsite at least quarterly and as business needs require.

ESSENTIAL DUTIES AND RESPONSIBILITIES

• Clinical Strategy & Execution: Provide executive oversight for the design, planning and execution of clinical development programs across assigned therapeutic areas or assets.
• Lead the development and implementation of clinical development plans aligned with Rigel's product strategy, registration pathways and lifecycle management objectives.
• Ensure high quality execution of clinical trials including protocol development, data collection, analysis and reporting in compliance with GCP, regulatory and medical standards.
• Oversee preparation and review of key clinical documents including protocols, investigators' brochures, clinical study reports and regulatory submission materials.
• Organizational & Cross-functional Leadership: Serve as a senior Clinical Development representative on cross-functional project teams, governance committees and internal review bodies.
• Partner with Clinical Operations and external CROs to ensure efficient trial execution, appropriate medical monitoring and adherence to safety and quality standards.
• Collaborate with Drug Safety to ensure ongoing evaluation of safety data and integration of pharmacovigilance considerations into clinical programs.
• Contribute to enterprise decision making through participation in portfolio reviews, investment discussions and development governance forums.
• Regulatory & External Engagement: Support interactions with global Health Authorities by contributing to briefing packages, responses and strategic positioning for assigned programs.
• Engage with external experts, investigators, key opinion leaders and advisory boards to inform clinical strategy and execution.
• Provide clinical development input to Business Development activities including due diligence for potential in-licensing or partnering opportunities.
• Strategic Contribution: Translate emerging clinical data into actionable insights to inform development decisions and portfolio strategy.
• Support the CMO in shaping long-term clinical development capabilities, processes and talent.

KNOWLEDGE AND SKILL REQUIREMENTS

• MD degree; advanced knowledge in hematology/oncology required.
• Board certification in hematology or oncology preferred.
• Minimum of 8 years of experience in clinical research or drug development (Phase 1 through 4) in an academic or industry environment; 6 years in an industry pharmaceutical or biotech setting.
• Experience leading or supporting interactions with global Health Authorities and contributing to regulatory strategy.
• Demonstrated ability to evaluate, interpret and communicate complex scientific and clinical data to inform development and portfolio decisions.
• Thorough knowledge of Good Clinical Practice, statistics and clinical trial design.
• Proven executive level leader with experience driving clinical development strategies and delivering high quality outcomes across multiple stakeholders.
• Significant experience working cross-functional within a matrixed organization and establishing productive scientific partnerships with external experts.
• Excellent executive communication verbal and written and presentation skills with the ability to influence internal and external stakeholders.

COMPENSATION AND BENEFITS

The anticipated salary range for this position is 336,000 to 405,000. The actual salary offered will depend on several factors including experience, qualifications, geographic location, internal equity and business needs.

This position is eligible to participate in Rigel's annual bonus program and is eligible for equity incentive awards subject to the terms of the applicable plans. This position is not commission based.

Rigel offers eligible employees a comprehensive benefits package including medical, dental and vision coverage; life and disability insurance; flexible spending accounts; a 401(k) plan; paid time off; paid company holidays; and other benefits.

WORKING CONDITIONS & PHYSICAL DEMANDS

While performing the duties of this job the employee is required to stand, walk, sit, talk and hear. Specific vision abilities required by this job include close vision, distance vision, peripheral vision, depth perception and the ability to adjust focus.

WORK ENVIRONMENT

The noise level in the work environment is usually moderate. Some travel may be required.

EQUAL OPPORTUNITY EMPLOYER

Rigel Pharmaceuticals Inc is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, genetic information, national origin, protected veteran status, disability status or any other characteristic protected by the law.