VP Clinical Development

Verto People; Somerville (MA); Remote; USD 250,000 - 360,000; Full time

Job summary

Verto People Ltd in the United States is seeking a Vice President of Clinical Development for Immunology/Biologics. You will lead global early-stage programs from candidate selection through FIH and Phase 2a PoC, shaping clinical strategy and cross-functional execution.

The ideal candidate holds an MD or MD-PhD, 7–10+ years in biotech/pharma, with strong immunology and biologics experience, and a track record of regulatory success and leadership.

Qualifications

• MD or MD-PhD qualification is essential.
• 7–10+ years of clinical development experience.
• Strong immunology/immune-mediated diseases background.
• Experience leading global early-phase programs (FIH, Phase 1/2a).
• Biologics development experience.
• IND/CTA submissions and regulatory knowledge.
• Leadership of cross-functional teams and CRO management.
• Ability to guide strategy from candidate selection to PoC.
• Excellent communication and stakeholder management.
• Ability to work in fast-paced biotech environment.

Responsibilities

• Define and lead global early-stage immunology development strategies.
• Oversee trial design, monitoring, and data interpretation.
• Lead dose selection and endpoints strategy.
• Mentor Clinical Leads and Scientists.
• Oversee IND/CTA readiness and First-in-Human studies.
• Collaborate with cross-functional teams and external CROs.
• Interface with regulatory authorities and key partners.
• Identify risks and mitigation strategies.
• Present updates to executive leadership.

Skills

Strategic leadership

Cross-functional leadership

Clinical development

Regulatory understanding

Biologics experience

IND/CTA submissions

Stakeholder management

Immunology expertise

Trial design oversight

Education

MD or MD-PhD

Job description

Vice President, Clinical Development - Immunology / Biologics

Location: United States | Remote
Employment: Full-Time | Permanent
Level: Vice President
Therapeutic Area: Immunology / Immune-Mediated Diseases

Are you an experienced Clinical Development leader with a strong background in immunology and early-stage drug development? This is an exciting opportunity to join an innovative, rapidly growing biotechnology company leveraging AI-driven drug discovery and next-generation biologics to develop breakthrough therapies for patients with immune-mediated diseases.

We are seeking a strategic, hands-on VP of Clinical Development to lead global clinical development programmes from candidate selection and IND-enabling activities through First-in-Human (FIH), Phase 1, Phase 1b and Phase 2a Proof-of-Concept (PoC) studies. The successful candidate will thrive in a fast-paced biotech environment, combining strong medical and scientific judgement with the ability to lead cross-functional teams, shape clinical strategy and drive critical development decisions.

Key Responsibilities:

• Define and lead global clinical development strategies across early-stage immunology programmes, from preclinical development through Phase 2a Proof-of-Concept.

• Oversee clinical trial design, protocol development, medical monitoring, safety assessments and clinical data interpretation.

• Lead critical decisions relating to dose selection, patient populations, study endpoints, biomarkers and indication strategy.

• Provide scientific leadership, guidance and mentorship to Clinical Leads and Clinical Scientists.

• Lead the transition of preclinical candidates into clinical development, including IND/CTA readiness and First-in-Human studies.

• Partner closely with Clinical Operations to oversee CROs, external vendors, trial timelines, budgets and study delivery.

• Collaborate with Regulatory Affairs, Translational Medicine, Clinical Pharmacology, CMC, Safety and Research teams to ensure integrated development strategies.

• Lead interactions with regulatory authorities, key opinion leaders and external development partners.

• Identify clinical, scientific and regulatory risks, implementing effective mitigation strategies.

• Present clinical development strategies, programme updates and investment recommendations to executive leadership.

Candidate Requirements:

• MD or MD-PhD qualification - essential.

• 7-10+ years of clinical development experience within the biotechnology or pharmaceutical industry.

• Strong experience in immunology or immune-mediated diseases, including dermatology, rheumatology, gastroenterology or respiratory indications.

• Proven experience leading global early-phase clinical development programmes, particularly FIH, Phase 1 and Phase 2a PoC studies.

• Experience developing biologics, monoclonal antibodies, multispecific antibodies or other innovative therapeutic modalities.

• Strong understanding of IND/CTA submissions, clinical trial design, regulatory requirements and clinical safety monitoring.

• Demonstrated experience leading cross-functional clinical development teams and managing external CROs and vendors.

• Ability to interpret emerging clinical and translational data to guide development strategy and decision-making.

• Excellent strategic leadership, communication and stakeholder management skills.

• Comfortable working in a fast-paced, entrepreneurial biotechnology environment.

What's on Offer?

• Senior executive leadership opportunity within an innovative, rapidly growing biotechnology company.

• Opportunity to shape the clinical development strategy for a pipeline of next-generation immunology therapies.

• Exposure to cutting-edge AI-enabled drug discovery and biologics development.

• Significant influence over clinical programmes, portfolio decisions and future development strategy.

• Opportunity to lead global clinical development programmes from preclinical stages through clinical Proof-of-Concept and beyond.

• Collaborative, science-driven environment with direct exposure to executive leadership and strategic development partners.