Vice President, Portfolio Sales

Revolution Medicines; United States; On-site; USD 294,000 - 367,000; Full time

Job summary

Revolution Medicines seeks a visionary Vice President of Portfolio Sales and Field Team to design, build, and scale a national oncology sales organization in the United States. The role reports to the SVP of US Marketing & Field and drives launches, revenue growth, and field excellence across oncology indications.

The ideal candidate brings 25+ years in biopharmaceuticals with major oncology leadership, a proven ability to develop leaders, and a strong cross-functional approach, including

Qualifications

• Bachelor’s degree required; MBA/PhD preferred.
• 25+ years of biopharmaceutical industry experience, including oncology leadership.
• Proven track record building and scaling sales organizations and leading oncology launches.

Responsibilities

• Architect and build a national portfolio oncology sales organization with leaders and reps.
• Define and execute national sales strategy across oncology indications and launches.
• Oversee forecasting, incentive design, territory alignment, analytics, and training.
• Lead executive engagement with top national accounts to drive access and partnerships.
• Collaborate with Marketing, Market Access, Medical Affairs, and Training to align execution.
• Ensure adherence to regulatory, legal, and compliance standards.

Skills

Leadership

Strategic thinking

Cross-functional collaboration

Travel readiness

Education

Bachelor’s degree

MBA

PhD

Job description

Vice President, Portfolio Sales and Field Team

Location: Remote (United States)

Department: US Sales

Revolution Medicines is a global, commercial-state oncology company dedicated to discovering, developing and delivering innovative medicines for patients with RAS-addicted cancers. Leveraging its differentiated RAS(ON) tri-complex inhibitor platform, the company is advancing a broad, integrated portfolio of oral RAS(ON) inhibitors designed to directly target the active, cancer-driving state of RAS.Founded on rigorous scientific inquiry and a willingness to challenge long-held assumptions, Revolution Medicines is committed to changing the trajectory of disease for patients with RAS-addicted cancers worldwide.

Our people are united by a shared way of working: follow the science, challenge assumptions, act with urgency and hold ourselves to a high standard of rigor—all in service of patients.

The Opportunity:

The Vice President, Oncology Sales will lead the design, build, and execution of a high-performing, national oncology sales organization supporting Revolution Medicines products/services to the oncology communityg. Reporting to the SVP of US Marketing & Field, the VP will be responsible for creating and scaling a best-in-class sales organization, ensuring successful product launches, and driving sustained revenue growth. This leader will combine strategic vision with operational rigor, leveraging deep oncology expertise and cross-functional collaboration to position the organization for long-term success.

Key Responsibilities:

Organizational Build & Leadership

• Architect and execute the build-out of a national portfolio oncology sales organization, including hiring, onboarding, and development of regional leaders, account directors, and sales representatives.
• This will include nurse educator and other field facing roles or functions including sales operations and training.
• Establish organizational structure, roles, and deployment strategy aligned to brand objectives and market dynamics.
• Foster a high-performance culture grounded in accountability, collaboration, innovation, and patient-centricity.
• Develop leadership bench strength through coaching, succession planning, and talent development initiatives.

Strategic & Commercial Leadership

• Define and execute the national sales strategy across oncology indications, ensuring alignment with corporate objectives and brand strategies.
• Lead all aspects of product launch readiness and execution, including field deployment, targeting, messaging alignment, and performance tracking.
• Partner with Commercial Leadership Team to shape enterprise-wide strategy, providing field insights and actionable recommendations.
• Drive achievement of all revenue and performance targets, ensuring consistent delivery against quarterly and annual goals.

Sales Operations & Execution Excellence

• Oversee development and execution of key commercial levers including: Forecasting and demand planning, Incentive compensation design, Territory alignment and targeting, Performance analytics and reporting, Training and capability development programs.
• Ensure disciplined execution of business plans and continuous optimization based on market feedback and data insights.

Key Account & Market Engagement

• Lead strategy and executive engagement for top national accounts, including major health systems, IDNs, oncology networks, and GPOs.
• Oversee development and execution of strategic account plans that drive access, adoption, and long-term partnerships.
• Serve as a senior external representative of the company with key stakeholders and decision-makers.

Cross-Functional Collaboration

• Partner closely with Marketing, Market Access, Medical Affairs, Commercial Operations, and Training to ensure aligned execution.
• Lead cross-functional initiatives to address business challenges, optimize launch performance, and enhance customer experience.
• Act as the “voice of the field” to inform brand strategy, pipeline planning, and organizational priorities.
• Shape clinical development planning and prioritization.

Compliance & Governance

• Ensure all field activities adhere to regulatory, legal, and compliance standards.
• Model and reinforce ethical leadership and decision-making across the organization.

Required Skills, Experience and Education:

• Bachelor’s degree required; advanced degree (MBA, PharmD, PhD) preferred.
• 25+ years of biopharmaceutical industry experience, including significant oncology leadership.
• Proven track record of building and scaling sales organizations, preferably in small-to-mid-size biotech environments.
• Demonstrated success leading oncology product launches, including oral oncolytics.
• Prior leadership of second-line leaders (e.g., regional directors managing managers and reps).
• Deep expertise in oncology market dynamics, including GI, NSCLC preferred.
• Strong strategic, analytical, and operational leadership capabilities.
• Experience working in highly cross-functional, matrixed organizations.
• Willingness to travel (~50%).

Preferred Skills:

• Experience in NSCLC and/or GI oncology markets.
• Broad understanding of commercial functions including market access, marketing, training, and sales operations.
• Demonstrated ability to influence at executive levels internally and externally.
• Strong project management and organizational skills, with the ability to manage multiple priorities.
• Proven ability to build culture and lead through change in high-growth environments.

Base Pay Salary Range

The base pay salary range for this full-time position is listed below. Please note that base pay salary is one part of the overall total rewards program at RevMed, which includes competitive cash compensation, robust equity awards, strong benefits, and significant learning and development opportunities. In addition, some positions may include eligibility to earn commissions/bonus based on company and/or individual performance.

Note: No amount of pay is considered to be wages or compensation until such amount is earned, vested, and determinable. The amount and availability of any bonus, commission, incentive, field kit benefits, or any other form of compensation and field kit benefits that are allocable to a particular employee remains in the Company's sole and absolute discretion unless and until paid and may be modified at the Company’s sole and absolute discretion, consistent with applicable law.

Revolution Medicines is an equal opportunity employer and prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, disability, marital status, medical condition, and veteran status.

Revolution Medicines takes protection and security of personal data very seriously and respects your right to privacy while using our website and when contacting us by email or phone. We will only collect, process and use any personal data that you provide to us in accordance with our CCPA Notice and Privacy Policy. For additional information, please contact [e-mail].

$294,000 — $367,000 USD