Vice President, Pharmaceutical Development

Kymera Therapeutics; Watertown (MA); On-site; USD 315,000 - 395,000; Full time

Job summary

Kymera Therapeutics in Watertown, MA, is seeking a leader to define and drive the company's pharmaceutical development strategy across the portfolio, aligning with development timelines and corporate priorities. You will oversee preformulation, biopharmaceutics, and formulation development for discovery through clinical programs, and manage external CROs/CDMOs to ensure quality and timelines.

The role requires a Ph.D.

Qualifications

• Ph.D. in Pharmaceutics, Pharmaceutical Sciences, Chemical Engineering, or related discipline with 18 years of relevant pharmaceutical industry experience.
• Demonstrated success leading pharmaceutical development strategy from discovery through clinical development, with experience supporting commercialization readiness.
• Strong understanding of preformulation, biopharmaceutics, formulation development, and oral solid dose drug product manufacturing for small molecules.
• Deep expertise in formulation approaches for poorly soluble compounds, including enabling technologies to improve bioavailability and product performance.
• Proven track record of advancing programs through IND and clinical development milestones and contributing to successful regulatory submissions.
• Strong knowledge of GMP requirements, regulatory expectations, and evolving industry trends.
• Experience building and managing high-performing teams and external partnerships.
• Excellent communication and leadership skills, with the ability to engage technical teams and regulatory agencies.

Responsibilities

• Define and lead the company’s pharmaceutical development strategy across the portfolio, ensuring alignment with priorities and timelines.
• Provide strategic leadership for preformulation, biopharmaceutics, and formulation development activities supporting discovery through clinical programs.
• Champion innovation in formulation sciences and enabling technologies to address delivery and bioavailability challenges.
• Drive development and implementation of phase-appropriate drug product development and manufacturing strategies.
• Lead a Pharmaceutical Development team and manage external CROs, CDMOs, and strategic partners.
• Establish scalable processes and best practices to support portfolio growth and timely execution.
• Provide strategic oversight of outsourced development and manufacturing activities, ensuring quality and timelines.

Skills

Strategic leadership

IND/clinical development

Regulatory submissions

Cross-functional leadership

External partnerships

Education

Ph.D. in Pharmaceutics, Pharmaceutical Sciences, Chemical Engineering, or related discipline

Job description

Who we are:

Kymera is a clinical-stage biotechnology company pioneering the field of targeted protein degradation (TPD) to develop medicines that address critical health problems and have the potential to dramatically improve patients’ lives. Kymera is deploying TPD to address disease targets and pathways inaccessible with conventional therapeutics. Having advanced the first degrader into the clinic for immunological diseases, Kymera is focused on building an industry-leading pipeline of oral small molecule degraders to provide a new generation of convenient, highly effective therapies for patients with these conditions. Founded in 2016, Kymera has been recognized as one of Boston’s top workplaces for the past several years. For more information about our science, pipeline and people, please visit www.kymeratx.com or follow us on X (formerly Twitter) or LinkedIn.

How we work:

• PIONEER: We are courageous, resilient and rigorous in our mission to improve patients’ lives through our revolutionary degrader medicines.
• COLLABORATE: We value trust transparency from everyone. Our goals are shared, our decisions data-driven and our camaraderie genuine.
• BELONG: We recognize our differences, inviting curiosity and inclusivity, so that our people are valued, seen, and heard.

How you’ll make an impact:

• Define and lead the company’s pharmaceutical development strategy across the portfolio, ensuring alignment with corporate priorities and development timelines
• Provide strategic leadership for preformulation, biopharmaceutics, and formulation development activities supporting discovery, preclinical, and clinical-stage programs
• Champion innovation in formulation sciences and enabling technologies to address complex drug delivery and bioavailability challenges
• Drive development and implementation of phase-appropriate drug product development and manufacturing strategies
• Lead a high-performing Pharmaceutical Development team, in internal activities and management of an external network of CROs, CDMOs, and strategic partners
• Establish scalable processes, operational frameworks, and best practices to support portfolio growth
• Provide strategic oversight of outsourced development and manufacturing activities, ensuring quality, timelines, and technical objectives are achieved
• Lead CMC-related regulatory strategy for drug product development activities, regulatory submissions and health authority interactions
• Ensure compliance with applicable GMP and regulatory requirements
• Represent Pharmaceutical Development in due diligence activities, external collaborations, and interactions with other functions
• Contribute to risk assessment, resource prioritization, and investment decisions as a member of the Technical Operations leadership team
• Foster strong cross-functional partnerships across Research, Clinical, Regulatory, Quality, Supply Chain, and Program Management to enable efficient advancement of pipeline programs

Skills and experience you’ll bring:

• Ph.D. in Pharmaceutics, Pharmaceutical Sciences, Chemical Engineering, or related discipline with 18 years of relevant pharmaceutical industry experience
• Demonstrated success leading pharmaceutical development strategy from discovery through clinical development, with experience supporting commercialization readiness
• Strong understanding of preformulation, biopharmaceutics, formulation development, and oral solid dose drug product manufacturing for small molecules
• Deep expertise in formulation approaches for poorly soluble compounds, including application of enabling technologies to improve bioavailability and product performance
• Proven track record of advancing programs through IND and clinical development milestones and contributing to successful regulatory submissions
• Strong knowledge of GMP requirements, regulatory expectations, and evolving industry trends
• Experience building and managing high-performing teams and external partnerships
• Excellent communication and leadership skills, with the ability to effectively engage technical teams, executive leadership, external partners, and regulatory agencies

Equal Employment Opportunity

Kymera Therapeutics is proud to be an equal opportunity employer, seeking to create a welcoming and diverse environment. All applicants will receive consideration for employment without regard to race, color, religion, creed, gender, national origin, age, disability, veteran status, pregnancy, sex, marital status, gender expression or identity, genetic information, sexual orientation, citizenship, or any other legally protected class.

Compensation

• Kymera offers a competitive compensation package that recognizes both results and capabilities through market-based, performance-driven pay.
• The anticipated base salary range for this role is $315,000 — $395,000, with eligibility for annual bonus, equity participation, and comprehensive benefits.
• Actual salary is based on a holistic evaluation of the specific role/level as well as each candidate’s depth of experience and the capabilities they bring to the position.