Vaccine Design & Structural Biology Scientist

University of Washington; Seattle (WA); On-site; USD 99,000 - 122,000; Full time

Job summary

The University of Washington in Seattle, WA is seeking a research professional to lead and contribute to vaccine and therapeutic development targeting human pathogens. The role focuses on structure-based immunogen design, protein expression, and high-throughput cryo-EM studies of viral glycoproteins.

Responsibilities include performing design and experiments, characterizing antigenicity, conducting structural studies, and mentoring staff and postdocs.

Qualifications

• Master's Degree in Biochemistry or related field; four years of related experience required.
• Experience with cryo-electron microscopy, virology assays, and protein expression in mammalian cells.
• Familiarity with purification techniques and relevant safety protocols.

Responsibilities

• 20% Structure-based and machine-learning immunogen design for vaccines and proteins.
• 20% Characterize protein antigenicity using binding assays.
• 15% Perform structural studies with cryo-EM and X-ray crystallography.
• 10% Design and execution of virology assays.
• 10% Data analysis to inform research strategy.
• 10% Lead projects and major tasks.
• 5% Provide guidance to staff, students and postdocs, and collaborate with partners.

Education

Master's Degree in Biochemistry or related field

Tools

Cryo-electron microscopy

Virology assays

Protein expression in mammalian cells

Purification

Job description

The University of Washington in Seattle, WA is seeking a research professional to lead and contribute to vaccine and therapeutic development targeting human pathogens. The role focuses on structure-based immunogen design, protein expression, and high-throughput cryo-EM studies of viral glycoproteins.

Responsibilities include performing design and experiments, characterizing antigenicity, conducting structural studies, and mentoring staff and postdocs.