Upstream Process Development Scientist

Eurofins US Network; Boston (MA); On-site; USD 44,000 - 50,000; Full time

Benefits offered by this job

Medical, dental, vision

Life and disability insurance

401(k) with company match

Paid vacation and holidays

Bonus opportunities

Job summary

Eurofins USA PSS Insourcing Solutions in Boston is seeking an Upstream Scientist to support LVV production for gene therapy programs. This role focuses on executing production protocols in shake flasks and benchtop bioreactors, maintaining mammalian suspension cultures, and ensuring aseptic, compliant workflows.

You will collaborate with cross-functional teams to coordinate testing, document data in electronic notebooks, and drive process improvements.

Qualifications

• B.S. in Biology, Biochemistry, Biological Engineering or a related field with at least 1 year of relevant industry experience.
• M.S. in Biology, Biochemistry, Biological Engineering or a related field with at least 6 months of relevant industry experience.
• Proficient in mammalian suspension cell culture operations.
• Strong aseptic technique, with BSC experience.
• Experience with buffer and media preparation.
• Experience documenting results in electronic lab notebooks.
• Meticulous attention to detail in sample tracking and data recording.
• Ability to multi-task and manage workflows.
• Strong team orientation and communication.
• Authorization to work in the United States indefinitely without sponsorship.

Responsibilities

• Execute LVV production protocols using shake flasks and benchtop bioreactors.
• Maintain suspension cell cultures with aseptic technique.
• Coordinate analytical testing and cross-functional material exchange.
• Maintain lab stocks and equipment for the upstream team.
• Document process data in electronic lab notebooks and discuss observations in meetings.

Skills

Mammalian cell culture

Aseptic technique

BSC operations

Buffer & media prep

Electronic lab notebooks

Data recording

Multi-tasking

Team oriented

Communication skills

US work authorization

Education

B.S. in Biology, Biochemistry, Biological Engineering or related field

M.S. in Biology, Biochemistry, Biological Engineering or related field

Tools

Shake flasks

Benchtop bioreactors

Peristaltic pumps

Tube welders

Job description

Boston, MA, USA

Full-time

Company Description

The work we do at Eurofins Professional Scientific Services matters, and so do our employees. At Eurofins PSS, we put a focus on your professional growth. We provide our employees the ability to break into the biopharmaceutical industry and grow from the bottom up. We have the supportive teams and tools available to invest in you while also affording you work-life balance and a competitive benefits package.

Eurofins Scientific is an international life sciences company, providing a unique range of analytical testing services to clients across multiple industries, to make life and our environment safer, healthier and more sustainable. From the food you eat, to the water you drink, to the medicines you rely on, Eurofins works with the biggest companies in the world to ensure the products they supply are safe, their ingredients are authentic and labelling is accurate. Eurofins believes it is a global leader in food, environmental, pharmaceutical and cosmetics products testing and in agroscience CRO services. It is also one of the global independent market leaders in certain testing and laboratory services for genomics, discovery pharmacology, forensics, CDMO, advanced material sciences and in the support of clinical studies.

Job Description

Position Overview:

Our Eurofins PSS team is seeking an Upstream Scientist to work onsite supporting our client's upstream process development activities related to the production of sterile, injectable lentiviral vector (LVV)-based gene therapy products. The successful candidate will help support the execution and optimization of LVV production protocols, maintenance of mammalian suspension cell culture systems, process robustness, and yield-improvement studies. This role partners closely with cross-functional teams across the CMC project teams to support all upstream operations for the client's program. This is an excellent opportunity for a detail-oriented scientist to contribute directly to the development of novel gene therapy products from an established, hands-on upstream role.

Job Responsibilities:

• Execute LVV production protocols using shake flasks and benchtop bioreactors to support ongoing process development and characterization studies.
• Support routine maintenance of suspension cell cultures, applying strong aseptic technique and sterile workflow practices to preserve culture health and integrity.
• Collaborate with cross-functional teams to coordinate analytical testing, exchange materials, share technical observations, and align on project timelines.
• Maintain lab stocks, supplies, and equipment specific to the upstream team to support daily operations.
• Document process data in electronic lab notebook and shared databases and communicate key observations in team meetings.

Qualifications

Basic Minimum Qualifications:

• B.S. in Biology, Biochemistry, Biological Engineering or a related field with at least 1 year of relevant industry experience OR M.S. in Biology, Biochemistry, Biological Engineering or a related field with at least 6 months of relevant industry experience.
• Proficient in mammalian suspension cell culture operations, including execution of established production protocols for routine culture maintenance and shake flask seed train expansion.
• Strong aseptic technique, with hands-on experience working within a biosafety cabinet (BSC) to maintain sterile, contamination-free workflows.
• Experience with buffer and media preparation to support ongoing cell culture operations.
• Experience documenting process results in electronic lab notebooks and effectively communicating experimental observations to management and cross-functional team.
• Meticulous attention to detail in sample tracking, experiment execution, data recording, and laboratory documentation.
• Ability to set priorities and multi-task activities to effectively manage workflows and drive deliverables to completion.
• Strong team orientation, with excellent organizational skills, self-motivation, and a positive attitude.
• Strong communication skills, with the ability to clearly communicate experimental results and observations.
• Authorization to work in the United States indefinitely without restriction or sponsorship.

Preferred Qualifications:

• Previous experience with viral vector, cell therapy, gene therapy, or related biologics process development.
• Hands-on experience operating and maintaining laboratory equipment, including shake flasks, benchtop bioreactor systems, peristaltic pumps, and tube welders.
• Experience performing cell banking activities to support consistent, well-characterized starting material for upstream production.
• Familiar with gene delivery techniques such as transient transfection.

Additional Information

This role is a full-time, permanent position Monday-Friday 8am-5pm with occasional weekend/holiday work, as well as periodic work outside of working hours.

Excellent full-time benefits include:

• Comprehensive medical coverage, dental, and vision options
• Life and disability insurance
• 401(k) with company match
• Paid vacation and holidays
• Eligibility for yearly goal-based bonus & merit-based increases
• Compensation: $32.00-$36.00 per hour based on education and relatable industry experience.

Eurofins USA PSS Insourcing Solutions is a Disabled and Veteran Equal Employment Opportunity employer.