UNIV - Post Doctoral Scholar - Department of Neuroscience

Medical University of South Carolina (MUSC); Charleston (SC); On-site; USD 52,000 - 66,000; Full time

Job summary

The Taniguchi Lab at Medical University of South Carolina (MUSC) invites applications for a postdoctoral scholar to investigate experience-dependent gene expression and epigenetic mechanisms in the brain using mouse models. The project focuses on DNA hybrids, chromatin regulation, and transcriptional control, employing molecular, genomic, and behavioral techniques.

The successful candidate will design and conduct independent research, perform in vivo and molecular experiments, analyze data,

Qualifications

• PhD in neuroscience or a closely related field.
• Experience with molecular biology and genomic approaches.
• Experience with mouse behavioral experiments and in vivo studies.

Responsibilities

• Design and conduct independent research on gene expression and epigenetic regulation in the brain.
• Plan and execute experiments, collect and analyze data, develop molecular/genetic approaches, and prepare manuscripts and grant proposals.
• Collaborate with lab members and investigators and train junior researchers.

Skills

Molecular biology

Genomics

Chromatin

Behavioral neuroscience

Education

PhD in Neuroscience

Tools

Immunohistochemistry

Viral constructs

Job description

Job Description Summary
The Taniguchi Lab investigates how experience-dependent gene expression and epigenetic mechanisms in the brain contribute to long-lasting behavioral plasticity. The postdoctoral scholar will study molecular mechanisms of gene regulation, including DNA hybrid R-loops, chromatin regulation, and transcriptional mechanisms, using molecular, genomic, and behavioral approaches in mouse models.

Entity
Medical University of South Carolina (MUSC - Univ)

Worker Type
Employee

Worker Sub-Type
Regular

Cost Center
CC000984 COM NEURO RES Operations CC

Pay Rate Type
Salary

Pay Grade
University-00
Pay Range
0.00 - 0.00 - 0.000

Scheduled Weekly Hours
40

Work Shift

Job Description

Job Summary:

The Taniguchi Lab investigates how experience-dependent gene expression and epigenetic mechanisms in the brain contribute to long-lasting behavioral plasticity. The postdoctoral scholar will study molecular mechanisms of gene regulation, including DNA hybrid R-loops, chromatin regulation, and transcriptional mechanisms, using molecular, genomic, and behavioral approaches in mouse models.

Job Description:

The postdoctoral scholar will design and conduct independent research projects investigating gene expression and epigenetic regulation in the brain. Responsibilities will include experimental design, data collection and analysis, development of molecular and genetic approaches, preparation of manuscripts and grant applications, and collaboration with other laboratory members and investigators.

Job Duties:

35%
Conduct molecular and cellular neuroscience experiments, including gene expression analysis, chromatin assays, molecular cloning, immunohistochemistry, and development of viral constructs for gene and protein manipulation. Perform and optimize experiments using mouse brain tissue and cultured cells.

35%

Conduct in vivo neuroscience studies, including mouse behavioral experiments, brain tissue collection, stereotaxic surgery, and molecular or genetic manipulation of specific brain regions. Maintain accurate experimental records and troubleshoot experimental procedures.

30%

Analyze and interpret experimental data, prepare figures, abstracts, manuscripts, and grant applications, and present research findings. Collaborate with other investigators and laboratory members and provide guidance and training to junior researchers and students.

Additional Job Description
Physical Requirements: (Note: The following descriptions are applicable to this section: Continuous - 6-8 hours per shift; Frequent - 2-6 hours per shift; Infrequent - 0-2 hours per shift) Ability to perform job functions in an upright position. (Continuous) Ability to perform job functions in a seated position. (Continuous) Ability to perform job functions while walking/mobile. (Frequent) Ability to climb stairs. (Infrequent) Ability to work indoors. (Continuous) Ability to work in all cold temperature extremes, i.e. spot coolers. (Frequent) Ability to bend at the waist. (Frequent) Ability to twist at the waist. (Frequent) Ability to perform 'pinching' operations. (Continuous) Ability to fully use both hands/arms. (Continuous) Ability to perform repetitive motions with hands/wrists/elbows and shoulders. (Continuous) Ability to fully use both legs. (Continuous) Ability to reach in all directions. (Continuous) Possess good finger dexterity. (Continuous) Ability to maintain tactile sensory functions. (Continuous) Ability to maintain good olfactory sensory function. (Continuous) Ability to lift and carry 15 lbs., unassisted. (Frequent) Ability to lift objects, up to 15 lbs., from floor level to height of 72 inches, unassisted. (Frequent) Ability to lower objects, up to 15 lbs., from height of 72 inches to floor level, unassisted. (Frequent) Ability to push/pull objects, up to 15 lbs., unassisted. (Infrequent) Ability to lift and carry objects up to 15 lbs. a distance of five (5) floors and to outlying buildings. (Frequent) Ability to maintain 20/40 vision, corrected. (Continuous) Ability to see and recognize objects close at hand. (Continuous) Ability to see and recognize objects at a distance. (Continuous) Ability to match or discriminate between colors. (Continuous) Ability to determine distance/relationship between objects; depth perception. (Continuous) Good peripheral vision capabilities. (Continuous) Ability to maintain hearing acuity, with correction. (Continuous) Ability to perform gross motor functions with frequent fine motor movements. (Continuous) Ability to be qualified physically (by medical personnel) for respirator use, initially and annually. Ability to work alone in isolated areas, such as darkrooms. (Frequent) Additional New Requirements: Ability to obtain and maintain a valid drivers license. Computer literacy. Ability to work rotating shifts as required. Ability to work overtime as required. Ability to learn and use new processes, tools and equipment as required.

If you like working with energetic enthusiastic individuals, you will enjoy your career with us!

The Medical University of South Carolina is an Equal Opportunity Employer. MUSC does not discriminate on the basis of race, color, religion or belief, age, sex, national origin, gender identity, sexual orientation, disability, protected veteran status, family or parental status, or any other status protected by state laws and/or federal regulations. All qualified applicants are encouraged to apply and will receive consideration for employment based upon applicable qualifications, merit and business need.

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