Translational Science Lead—Immunology & Omics

Initial Therapeutics, Inc.; Franklin Township (NJ); On-site; USD 168,000 - 221,000; Full time

Benefits offered by this job

Medical, dental & vision insurance

401(k) with company match

Paid parental leave

Flexible spending accounts

Job summary

Legend Biotech in Somerset, NJ, is seeking an Associate Director, Translational Science to bridge early discovery and clinical development. The role blends immunology with computational biology to drive translational strategies and biomarker programs across autoimmune and oncology areas.

You will lead high-dimensional data analyses (scRNA-seq, CITE-seq, flow cytometry, spatial transcriptomics) and collaborate with CROs and academia to advance MoA insights and patient stratification, while

Qualifications

• PhD or MD/PhD in Immunology, Bioinformatics, Computational Biology or related field.
• 5+ years in biopharma or academic translational leadership.
• Experience with genomic data analysis and data integration across datasets.
• Proven track record in biomarker development and clinical implementation.

Responsibilities

• Lead translational plans from lead optimization through Phase II trials.
• Oversee analysis of high-dimensional datasets to identify pharmacodynamic markers.
• Partner with Clinical Development to implement biomarker assays in protocols.
• Manage CROs and academic collaborators for assay development and data processing.
• Represent Translational Science on program teams and contribute to regulatory documents.
• Ensure compliance with regulatory requirements for biomarker-driven trials.
• Lead multiple programs in a fast-paced environment.

Skills

Translational strategy

Immunology

Bioinformatics

Computational biology

Data analysis

Biomarker development

Regulatory knowledge

Project management

Education

PhD or MD/PhD in Immunology, Bioinformatics, Computational Biology

Tools

scRNA-seq

CITE-seq

Flow cytometry

Spatial transcriptomics

Job description

Legend Biotech in Somerset, NJ, is seeking an Associate Director, Translational Science to bridge early discovery and clinical development. The role blends immunology with computational biology to drive translational strategies and biomarker programs across autoimmune and oncology areas.

You will lead high-dimensional data analyses (scRNA-seq, CITE-seq, flow cytometry, spatial transcriptomics) and collaborate with CROs and academia to advance MoA insights and patient stratification, while