Toxicology Research Scientist

Scorpion Therapeutics; Boston (MA); On-site; USD 110,000 - 170,000; Full time

Job summary

Vertex Pharmaceuticals seeks a preclinical safety scientist within its PISA group to develop and apply advanced in vitro models and computational approaches for evaluating safety risks of new candidate molecules.

Responsibilities include designing biochemical and cell-based assays, using automation for high-throughput screening, and investigating toxicity mechanisms while communicating findings to cross-functional teams.

Qualifications

• Bachelor's degree or higher required.
• Experience in academic or industry settings: 2+ years (PhD) or 5+ years (MS) or 8+ years (BS).
• Expertise in cell culture, assay development, immunoassays, and scripting (R, Python, MATLAB).
• Strong analytical skills and scientific communication.

Responsibilities

• Design and execute novel biochemical and cell-based assays.
• Leverage automation and data analytics for high-throughput screening.
• Investigate mechanisms of toxicity.
• Communicate findings to cross-functional teams.

Skills

Cell culture

Assay development

Immunoassays

R scripting

Python scripting

MATLAB scripting

Analytical skills

Scientific communication

Education

Bachelor's degree or higher

Job description

Role

Conduct preclinical safety assessments within Vertex's PISA group, supporting early-stage drug development by developing and applying advanced in vitro models and computational approaches to evaluate safety risks of new candidate molecules.

Responsibilities

independently design and execute novel biochemical and cell-based assays, leverage automation and data analytics for high-throughput screening, investigate mechanisms of toxicity, and communicate findings to cross-functional teams.

Requirements

• Bachelor's or higher degree
• 2+ years (PhD) or 5+ years (Master's) or 8+ years (Bachelor's) in academic or industry settings
• expertise in cell culture, assay development, immunoassays, and scripting (R, Python, MATLAB)
• strong analytical skills and scientific communication

Preferred

• experience with cellular immunophenotyping, multiplexed ELISA, and translational models
• background in drug safety, toxicology, or discovery pharmacology

High-Value

focus on safety assessment for novel drug modalities, integrating laboratory and computational science, supporting early discovery phases.

WorkSetup

on-site five days/week with ad hoc flexibility.