Territory Business Manager / Rare Disease

Syneos Health; Roanoke (VA); On-site; USD 110,000 - 165,000; Full time

Benefits offered by this job

Competitive compensation

Health, Dental and Vision benefits

Company match 401k

Flexible PTO and sick time

Job summary

Syneos Health in Roanoke, VA is seeking a Territory Business Manager to drive sales within a defined geography for a new rare disease GI/Hepatology product launched by the company. You will develop territory plans, build professional relationships with physicians and deliver high-impact, clinically focused presentations.

The role requires a life sciences or related degree, 5+ years pharma sales, and a track record of top-tier performance, with strong CRM/AI analytics and the ability to travel as

Qualifications

• Bachelor’s Degree in Life Sciences, Business or related field.
• 5+ years of pharmaceutical/biopharmaceutical sales experience.
• 3+ years of GI/Hepatology sales experience/rare disease preferred.
• Consistent track record of top-tier sales accomplishments.
• Experience calling on Gastroenterologists/Hepatologists in the territory preferred.
• Ability to learn complex scientific information and communicate effectively.
• Must be self-motivated with high autonomy and independence.
• Strong technical and analytical skills including CRM and AI tools.

Responsibilities

• Achieve and/or exceed sales goals within an assigned geography by executing an integrated territory plan.
• Establish and maintain professional relationships with targeted physicians.
• Succeed in a matrixed selling environment with cross-functional collaboration.
• Coordinate with FRMs, TLLs, Market Access, Medical, Marketing and Operations teams.
• Identify key influencers and manage interactions with top target customers.
• Use data tools and insights to guide business decision-making and strategies.
• Demonstrate account-based selling skills through group presentations and meetings.
• Plan and organize activities for regular territory coverage and travel as needed.
• Manage territory budget to support sales and marketing activities.
• Complete administrative tasks in a timely manner and align with brand strategy.
• Participate in training and development programs and maintain compliant practices.

Skills

Sales experience

GI/Hepatology/rare disease knowledge

Analytical skills

CRM proficiency

Microsoft Office proficiency

Autonomy

Education

Bachelor’s Degree in Life Sciences, Business or related field

Tools

CRM software

AI tools

Microsoft Office Suite

Job description

Territory Business Manager / Rare Disease

Updated: August 25, 2026
Location: Roanoke, VA, United States
Job ID:17457-OTHLOC-CMAwYfwA

We are launching a brand new rare disease GI/Hepatology team. This product is within the rare disease category and will be an exciting opportunity to launch a new product.

The Territory Business Manager (TBM) is responsible for achieving or exceeding sales goals within an assigned geography while operating in a compliant and ethical manner. This role develops and executes territory strategies, identifies customer needs, and drives pull-through by delivering high-impact, clinically focused presentations that clearly communicate therapeutic value. Using strong analytical skills, the TBM evaluates regional market data to build and implement strategic territory business plans, foster lasting professional relationships, and collaborate effectively with cross‑functional partners. The ideal candidate is collaborative, compliant, self‑motivated, results‑oriented, and entrepreneurial.

Responsibilities

• Achieve and/or exceed targeted DSE MBO and future sales goals in an assigned territory by developing, implementing and executing an integrated territory business plan encompassing key customers and accounts with the goal of maximizing sales.
• Establish and maintain professional relationships with targeted physicians to maximize new business opportunities.
• Achieve success in a complex, matrixed selling environment in which the need for collaboration and cross-functional discipline is critical.
• Cross-functional partners may consist of FRMs, TLLs, Market Access, Medical, Marketing and Operations colleagues.
• Identify key influencers and achieve designated customer interaction expectations with a focus on top target customers.
• Use data tools and insights, and other informational sources such as next best action, to determine strategies and tactics for business decision‑making.
• Demonstrate account-based selling skills (including group presentations, etc.).
• Plan and organize activities to ensure regular and consistent coverage of the territory according to a plan of action.
• Manage territory budget to support sales and marketing activities.
• Complete all administrative tasks in a timely manner.
• Execute the company’s DSE and future brand strategy and tactics within their assigned geographic area.
• Participation in training and development programs.
• Comply with all legal, regulatory and compliance policies and demonstrate a high level of integrity and professionalism at all times.
• Additional duties as required.

Requirements

• Bachelor’s Degree in Life Sciences, Business or a related field required
• 5+ years of pharmaceutical/biopharmaceutical sales experience
• 3+ years of GI/Hepatology sales experience/rare disease preferred
• Consistent track record of documented top‑tier sales accomplishments.
• Experience calling on Gastroenterologists/Hepatologists in the designated territory geography preferred
• Experience launching products in competitive marketplace
• Ability to learn complex scientific information, apply technical proficiency and effectively communicate
• Must be self‑motivated and able to work with a high level of autonomy and independence
• Strong technical & analytical skills including proficiency with CRM, AI tools and Microsoft Office Suite Proficiency with AI
• A valid driver’s license and ability to travel as needed, which may include overnight and/or weekend travel

At Syneos Health, we are dedicated to building a diverse, inclusive and authentic workplace. If your past experience doesn’t align perfectly, we encourage you to apply anyway. At times, we will consider transferable skills from previous roles. We also encourage you to join our Talent Network to stay connected to additional career opportunities.

Why Syneos Health?

Here, the work is challenging, and the pace is exhilarating. By joining one of our commercial teams, you’re empowered to succeed with the support, resources, and autonomy that you need. The diversification and breadth of our new and existing partnerships create a multitude of career paths and employment opportunities. Syneos Health has launched more sales teams in the last 5 years across all major therapeutic areas than the top 25 pharma companies combined. Join our game‑changing, global company dedicated to creating better, smarter, faster ways to get biopharmaceutical therapies to patients. Experience the thrill of knowing that your everyday efforts are contributing to improving patients’ lives around the world.

W o r k H e r e M a t t e r s E v e r y w h e r e | How are you inspired to change lives?

Syneos Health companies are affirmative action/equal opportunity employers (Minorities/Females/Veterans/Disabled)

At Syneos Health, we believe in providing an environment and culture in which Our People can thrive, develop and advance. We reward and recognize our people by providing valuable benefits and a quality‑of‑life balance. The benefits for this position will include:

• a competitive compensation package
• Health benefits to include Medical, Dental and Vision
• Company match 401k
• flexible paid time off (PTO) and sick time.

Because certain states and municipalities have regulated paid sick time requirements, eligibility for paid sick time may vary depending on where you work. Syneos Health complies with all applicable federal, state, and municipal paid sick time requirements.

Discover what our more than 25,000 employees already know: work here matterseverywhere. We work hard,and smart, all in the name of getting much‑needed therapies to thosewho need them most. A career with Syneos Health means your everyday workimprovespatients’ lives around the world. Selecting us as an employer secures acareer inwhich you’re guaranteed to:

Syneos Health® is a leading fully integrated biopharmaceutical solutions organization builtto accelerate customer success. We translate unique clinical, medical affairs and commercialinsights into outcomes to address modern market realities. To learn more visit syneoshealth.com .

Syneos Health is an Equal Opportunity Employer. All qualified applicants will receiveconsideration for employment without regard to race, color, age, religion, marital status,ethnicity, national origin, sex, gender, gender identity, sexual orientation, protectedveteran status, disability or any other legally protected status and will not bediscriminated against. If you are an individual with a disability who requires reasonableaccommodation to complete any part of our application process, including the use of thiswebsite, please contact us at: Email: [emailprotected] One of our staff members willwork with you to provide alternate means to submit your application.