Technician II Next Generation Sequencing

Charles River; Northern (KY); Hybrid; USD 30,000 - 47,000; Full time

Job summary

Charles River is hiring for an entry-level to associate level position in Wayne, PA to support Next Generation Sequencing testing services under direct supervision. You will perform laboratory tasks including reagent prep, aseptic technique, and data recording, following cGMP guidelines and SOPs.

Responsibilities include assays for DNA/RNA, PCR, library prep and sequencing, plus routine GMP reporting and data analysis. Strong attention to detail and teamwork are essential.

Qualifications

• 1–2 years related experience in biological lab.
• Knowledge of cGMPs or regulatory affairs preferred.
• Excellent interpersonal skills and communication abilities.

Responsibilities

• Perform laboratory activities necessary for next generation sequencing testing including but not limited to;
• Reagent preparation including buffers, chemical solutions, complex mixtures and media preparations according to standard test methods.
• Perform tasks using aseptic techniques including work within a biological safety cabinet.
• Participate in the general maintenance of laboratory equipment.
• Conduct aseptic growth and/or manipulation of bacteria, yeast, virus and mammalian cells.
• Make detailed observations and accurately and precisely record data, summarize data for reports and document all activities performed in accordance with current Good Manufacturing Practice (cGMP)
• Perform a variety of molecular biology-based laboratory experiments, test and procedures including isolation and analysis of DNA and RNA, PCR, library preparation and next generation sequencing;
• Write routine GMP reports.
• Report results of experiments, test, and procedures and analyze data.
• Efficiently organize and plan daily activities.
• Maintain a safe working environment by adhering to company policies and procedures.
• Follow all SOPs, STMs, and cGMP guidelines as they relate to specific tasks.
• Heightened awareness for the role of cGMP in daily activities.
• Assist in training of subordinate personnel on known tests and procedures.
• Perform all other related duties as assigned.

Skills

cGMP knowledge

Interpersonal skills

Microsoft Office

Education

Bachelor's degree in Biology

Job description

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Location: Wayne, PA, US, 19087

For 75 years, Charles River employees have worked together to assist in the discovery, development and safe manufacture of new drug therapies. When you join our family, you will have a significant impact on the health and well-being of people across the globe. Whether your background is in life sciences, finance, IT, sales or another area, your skills will play an important role in the work we perform. In return, we'll help you build a career that you can feel passionate about.

Job Description

Under direct supervision, responsible for performing daily laboratory tasks as they relate to Next Generation Sequencing Testing Services.

ESSENTIAL DUTIES AND RESPONSIBILITIES

• Perform laboratory activities necessary for next generation sequencing testing including but not limited to;


• Reagent preparation including buffers, chemical solutions, complex mixtures and media preparations according to standard test methods.


• Perform tasks using aseptic techniques including work within a biological safety cabinet;


• Participate in the general maintenance of laboratory equipment;


• Conduct aseptic growth and/or manipulation of bacteria, yeast, virus and mammalian cells;


• Make detailed observations and accurately and precisely record data, summarize data for reports and document all activities performed in accordance with current Good Manufacturing Practice (cGMP)


• Perform a variety of molecular biology-based laboratory experiments, test and procedures including isolation and analysis of DNA and RNA, PCR, library preparation and next generation sequencing;


• Write routine GMP reports.


• Report results of experiments, test, and procedures and analyze data.


• Efficiently organize and plan daily activities


• Maintain a safe working environment by adhering to company policies and procedures.


• Follow all SOPs, STMs, and cGMP guidelines as they relate to specific tasks.


• Heightened awareness for the role of cGMP in daily activities.


• Assist in training of subordinate personnel on known tests and procedures.


• Perform all other related duties as assigned.

QUALIFICATIONS

• Education: Bachelor's degree (B.A./B.S.) or equivalent in Biology or related discipline.


• Experience: 1 to 2 years related experience in biological lab.


• An equivalent combination of education and experience may be accepted as a satisfactory substitute for the specific education and experience listed above.


• Other: Knowledge of cGMPs or regulatory affairs pertaining to the pharmaceutical and biological industries is preferred. Must possess excellent interpersonal skills to maintain communication across biological functional groups. Able to communicate effectively in a group or one on one setting. Basic Microsoft Office skills are a plus.

Compensation Data

The pay rate for this role is $27.88 per hour. Please note that salaries vary within the range based on factors including, but not limited to, experience, skills, education, certifications, and location.

About Biologics Testing Solutions

With more than 50 years of experience and proven regulatory expertise, the Charles River Biologics group can address challenging projects for biotechnology and pharmaceutical companies worldwide. Offering a variety of services such as contamination and impurity testing, protein characterization, bioassays, viral clearance studies and stability and lot release programs, we support clients throughout the biologic development cycle, from the establishment and characterization of cell banks through preclinical and clinical studies to marketed products. Whether clients need stand-alone services, a unique package of testing, or insourced support, our Biologics group can create a custom solution to suit their needs. Each year more than 20,000 biologic testing reports are sent each and over 200 licenses products are supported by our biologics testing solutions team.

About Charles River

Charles River is an early-stage contract research organization (CRO). We have built upon our foundation of laboratory animal medicine and science to develop a diverse portfolio of discovery and safety assessment services, both Good Laboratory Practice (GLP) and non-GLP, to support clients from target identification through preclinical development. Charles River also provides a suite of products and services to support our clients’ clinical laboratory testing needs and manufacturing activities. Utilizing this broad portfolio of products and services enables our clients to create a more flexible drug development model, which reduces their costs, enhances their productivity and effectiveness to increase speed to market.

With over 20,000 employees within 110 facilities in over 20 countries around the globe, we are strategically positioned to coordinate worldwide resources and apply multidisciplinary perspectives in resolving our client’s unique challenges. Our client base includes global pharmaceutical companies, biotechnology companies, government agencies and hospitals and academic institutions around the world.

At Charles River, we are passionate about our role in improving the quality of people’s lives. Our mission, our excellent science and our strong sense of purpose guide us in all that we do, and we approach each day with the knowledge that our work helps to improve the health and well-being of many across the globe. We have proudly worked on 80% of the drugs approved by the U.S. Food and Drug Administration (FDA) in the past five years.

We’re committed to providing benefits that elevate your quality of life. Based on your position these may include: bonus/incentives based on performance, 401K, paid time off, stock purchase program, Health and wellness coverage, employee and family wellbeing support programs, and work life balance flexibility.

Charles River is an equal opportunity employer and is committed to providing equal employment opportunities for all qualified applicants and employees without regard to race, color, sex, religion, national origin, ancestry, age, mental or physical disability, family status, pregnancy, military or veteran status, or any other characteristic protected by federal, state, or local laws.

It is unlawful in some states (including Massachusetts) to require or administer a lie detector test as a condition of employment or continued employment. An employer who violates this law shall be subject to criminal penalties and civil liability.

For more information, please visit www.criver.com.

Nearest Major Market

Philadelphia

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Pharmaceutical, Biology, Molecular Biology, Chemical Research, Scientific, Science, Engineering