Technician - Biomanufacturing, Downstream/mRNA

Catalent; Madison (WI); On-site; USD 40,000 - 50,000; Full time

Benefits offered by this job

Defined career path

Generous 401(k) match

Medical, dental, and vision benefits

Tuition reimbursement

152 hours of PTO plus 8 paid holidays

Job summary

A leading global biopharmaceutical company in Madison, WI is seeking a Technician for their Manufacturing team. This entry-level role involves 100% on-site work from 10 pm to 8 am. Responsibilities include performing downstream purification activities and ensuring adherence to GMP standards. Candidates should have a High School Diploma or equivalent, with GMP experience preferred. The position offers a defined career path, generous benefits, and the opportunity to contribute to meaningful work in drug development.

Qualifications

• High School Diploma or equivalent plus at least two years of relevant experience.
• GMP manufacturing experience preferred.
• Ability to use Microsoft Office systems effectively.

Responsibilities

• Perform basic downstream purification and mRNA production activities.
• Follow Manufacturing Batch Production Records (BPRs) accurately.
• Proactively identify safety, quality, and efficiency improvements.

Skills

GMP manufacturing

Microsoft Word

Microsoft Excel

TrackWise

Chromatography

Education

High School Diploma or equivalent

Bachelor’s or Associate’s degree in a relevant discipline

Tools

DeltaV

ComplianceWire

Chromatography software

Job description

Job Summary

Catalent, Inc. is a leading global Contract Development and Manufacturing Organization (CDMO) located in Madison, WI. This 263,000‑sq. ft. GMP facility offers advanced mammalian cell line engineering and biomanufacturing capabilities using single‑use systems to support scalable production. The role is an entry‑level position in the Manufacturing team, with 100% on‑site work and a shift schedule of 10 pm–8 am on either Sunday‑Wednesday or Wednesday‑Saturday. The Technician will manufacture biopharmaceutical products within a clean‑room environment following detailed instructions and established procedures with frequent supervision.

Responsibilities

• Perform basic downstream purification and mRNA production activities, such as in‑vitro transcription (IVT) reactions, chromatography, tangential flow filtration (TFF), viral filtration, and column packing and qualification.
• Accurately follow manufacturing Batch Production Records (BPRs) and Standard Operating Procedures (SOPs) in accordance with current Good Manufacturing Practices (cGMPs) and focus on “right first time” execution.
• Document all activities in accordance with Good Documentation Practices (GDPs) in BPRs, forms, and other quality documentation.
• Recognize deviations from the intended procedure and raise awareness through the Rapid Response process.
• Proactively identify safety, quality, and efficiency improvements and actively participate in the Catalent Way continuous‑improvement culture.
• May lead “Just Do It” (JDI) continuous‑improvement activities and engage in the implementation of CI projects.
• May coach more junior team members on basic execution activities and act as an “onboarding buddy” to facilitate bringing new team members quickly up to speed on culture and basic workplace expectations.
• Perform general cleanroom housekeeping, including room and equipment cleaning, disposal of waste, and maintenance of 5S standards.
• Other duties as assigned.

Qualifications

• High School Diploma or equivalent plus at least two (2) years of relevant experience; alternatively, a Bachelor’s or Associate’s degree in a scientific, engineering, or biomanufacturing discipline without formal experience.
• GMP manufacturing experience preferred.
• Ability to use Microsoft Word and Excel and other Office systems.
• Preferred experience with TrackWise, ComplianceWire, JD Edwards, DeltaV, chromatography software.
• Physical requirements include frequent sitting, standing, walking, reading, talking, writing, listening; occasional stooping, kneeling, crouching, bending, carrying, grasping; frequent lifting or moving up to 10 lb. and occasional lifting or moving up to 50 lb.; must comply with EHS responsibilities and work in a clean‑room environment.

Benefits

• Defined career path and annual performance review and feedback process.
• Diverse, inclusive culture.
• Potential for career growth on an expanding team within an organization dedicated to preserving and bettering lives.
• 152 hours of PTO plus 8 paid holidays.
• Generous 401(k) match.
• Medical, dental, and vision benefits.
• Tuition reimbursement – let us help you finish your degree or start a new one.

Catalent offers rewarding opportunities to further your career! Join the global drug development and delivery leader and help us bring over 7,000 life‑saving and life‑enhancing products to patients around the world. Catalent is an exciting and growing international company where employees work directly with pharma, biopharma and consumer health companies of all sizes to advance new medicines from early development to clinical trials and to the market. Catalent produces more than 70 billion doses per year, and each one will be used by someone who is counting on us. Join us in making a difference.

Visit Catalent Careers to explore career opportunities.

Catalent is an Equal Opportunity Employer, including disability and veterans.

If you require reasonable accommodation for any part of the application or hiring process due to a disability, please submit your request by sending an email confirming your request for accommodation and including the job number, title, and location to [e-mail].