Technical Development Senior Associate Scientist

F. Hoffmann-La Roche AG; South San Francisco (CA); On-site; USD 93,000 - 172,000; Full time

Job summary

Genentech, a Roche subsidiary, seeks a scientifically curious researcher to advance CHO cell line development and TI expression technology. You will design and execute parallel experiments, develop cell lines expressing antibodies or therapeutic molecules, and help streamline TI CLD platform processes based in South San Francisco on site.

Ideal candidates have a strong foundation in molecular/cell biology, DNA manipulation, and gene copy number analysis, with familiarity in automation and

Qualifications

• Strong background in molecular and cell biology including DNA and cell manipulation.
• Experience with gene copy number analysis.
• Familiarity with automation and lab automation tools.
• Excellent communication and presentation skills, both verbal and written.
• Robust problem-solving abilities and collaborative work style.

Responsibilities

• Design and execute multiple experiments in parallel with minimal supervision.
• Develop cell lines expressing antibodies or other therapeutic molecules.
• Improve targeted integration (TI) CLD platform processes and efficiency.
• Support streamlining of TI CLD workflows and cell line development activities.

Skills

Molecular biology

Cell biology

DNA manipulation

Gene copy number analysis

Automation familiarity

Communication skills

Problem solving

Education

B.S./M.S. in molecular biology or related field

Job description

Technical Development Senior Associate Scientist Department Summary

We are seeking a creative, enthusiastic, and highly motivated researcher to develop cell lines expressing antibodies or other therapeutic molecules and improve cell line development processes. The successful candidate will learn stable CHO cell line development (CLD) for clinical and commercial manufacturing using Genentech’s industry-leading targeted integration (TI) expression technology. The candidate will be responsible for CLD, improving targeted integration efficiency, and help with streamlining and improving TI CLD platform processes. Familiarity with cell culture and stable cell line generation is preferred. A strong background in cell and molecular biology is required.

The Opportunity

This is an ideal position for a researcher who is enthusiastic about research, innovation, and gaining drug development experience. As such the position requires excellent communication skills and the desire to learn about and integrate multiple aspects of drug development. The selected individual is expected to work independently with minimal supervision to design and execute different experiments in parallel. This position is based in South San Francisco, on site.

Required Education

The candidate should have a B.S. or M.S. with 2+ years of experience in molecular biology, cell biology, biochemistry or other related disciplines.

Required Skills, Knowledge, and Abilities

The ideal candidate will possess expertise in Molecular and cell biology including DNA and cell manipulation. Gene copy number analysis. Familiarity with automation.

The candidate must be skilled in communication and presentation and should be able to clearly convey complex ideas and data both verbally and written.

Expectations for this position include a strong work ethic, ability to work well with others and robust problem-solving skills.

Relocation benefits are not available for this job posting.

The expected salary range for this position based on California is 92 600,00 - 172 000,00 USD Annual. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. A discretionary annual bonus may be available based on individual and Company performance. This position also qualifies for the benefits detailed at the link provided below.

Benefits

Genentech is an equal opportunity employer.

It is our policy and practice to employ, promote, and otherwise treat any and all employees and applicants on the basis of merit, qualifications, and competence.

The company's policy prohibits unlawful discrimination, including but not limited to, discrimination on the basis of Protected Veteran status, individuals with disabilities status, and consistent with all federal, state, or local laws.

If you have a disability and need an accommodation in relation to the online application process, please contact us by completing this form Accommodations for Applicants.

Who We Are

Genentech, a member of the Roche group and founder of the biotechnology industry, is dedicated to pursuing groundbreaking science to discover and develop medicines for people with serious and life‑tending diseases. To solve the world's most complex health challenges, we ask bigger questions that challenge our industry and the boundaries of science to transform society. Our transformational discoveries include the first targeted antibody for cancer and the first medicine for primary progressive multiple sclerosis. The next step is yours.

Genentech is an equal opportunity employer.

It is our policy and practice to employ, promote, and otherwise treat any and all employees and applicants on the basis of merit, qualifications, and competence.

The company's policy prohibits unlawful discrimination, including but not limited to, discrimination on the basis of Protected Veteran status, individuals with disabilities status, and consistent with all federal, state, or local laws.

If you have a disability and need an accommodation in relation to the online application process, please contact us by completing this form Accommodations for Applicants.