TDS Proteins CEAS Co-Op

6084-Janssen Research & Development, LLC Legal Entity; Spring House (PA); On-site; USD 40,000 - 50,000; Full time

Job summary

Johnson & Johnson’s Innovative Medicine division in Spring House, PA, seeks a Co-Op for six months (January–June 2027, flexible), full-time and on-site. The role supports cell line engineering, proteomics, metabolomics, and analytical platform development to advance biologics manufacturing.

The successful candidate will gain hands-on experience with CHO cell biology, LC-MS/MS analytics, and platform automation while collaborating with scientists to improve titer and product quality.

Qualifications

• Undergraduate freshman year completed and pursuing a Bachelor’s, Master’s or PhD in a related science.

Responsibilities

• Supporting cell line engineering and cell culture research activities focused on improving productivity, product quality, and manufacturing performance.
• Developing, optimizing, and implementing proteomics and metabolomics workflows to characterize cellular pathways and molecular drivers.
• Supporting the development of analytical platforms for cell line selection, characterization, and monitoring.
• Performing sample preparation, method development, and analysis for LC-MS/MS, mass spectrometry, proteomics, and metabolomics studies.
• Generating and analyzing Host Cell Protein (HCP) profiles to support cell line development and characterization.
• Supporting high-throughput and automated analytical workflows to improve efficiency and reproducibility.
• Developing and refining workflows for biological sample analysis and data interpretation.
• Investigating protein function and networks to identify targets that improve productivity and product quality.
• Collaborating with upstream teams on cell culture performance and process optimization.
• Operating analytical instrumentation and supporting technology transfer, validation, and implementation.

Skills

Mass spectrometry

Proteomics

Metabolomics

Cell culture

Analytical chemistry

Data analysis

Biology

Laboratory techniques

LC-MS/MS

Education

Bachelor’s degree (pursuing) in Biology/Chemistry/Biochemistry

GPA 3.0+

Tools

LC-MS/MS

Mass spectrometry software

Job description

At Johnson & Johnson,we believe health is everything. Our strength in healthcare innovation empowers us to build aworld where complex diseases are prevented, treated, and cured,where treatments are smarter and less invasive, andsolutions are personal.Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity.Learn more at jnj.com. As guided by Our Credo, Johnson & Johnson is responsible to our employees who work with us throughout the world. We provide an inclusive work environment where each person is considered as an individual. At Johnson & Johnson, we respect the diversity and dignity of our employees and recognize their merit.

Job Function

Career Programs

Job Sub Function

Non-LDP Intern/Co-Op

Job Category

Career Program

All Job Posting Locations

Spring House, Pennsylvania, United States of America

Job Description

About Innovative Medicine Our expertise in Innovative Medicine is informed and inspired by patients, whose insights fuel our science-based advancements. Visionaries like you work on teams that save lives by developing the medicines of tomorrow. Join us in developing treatments, finding cures, and pioneering the path from lab to life while championing patients every step of the way. Learn more at https://www.jnj.com/innovative-medicine

We are searching for the best talent for TDS Proteins CEAS Co-Op to be in Spring House, PA. 4 vacancies are currently available. The Co-op term is six months typically from January to June, 2027 (flexible). Full time requirement (40 hours per week) Fully On-site.

Purpose

The TDS Proteins Development Cell Engineering, Analytics & Screening (CEAS) organization is seeking a highly motivated Co-Op to support cell line engineering, proteomics, metabolomics, analytical platform development, and cell culture research initiatives that advance biologics development and manufacturing. This role provides hands-on experience in CHO cell biology, mass spectrometry-based analytics, quantitative proteomics and metabolomics, assay automation, and data analysis. The successful candidate will collaborate with scientists and engineers to investigate the molecular mechanisms that influence cell productivity, product quality, titer, and manufacturing performance while contributing to the development of next-generation analytical platforms that support cell line development and process optimization.

You will be responsible:

• Supporting cell line engineering and cell culture research activities focused on improving productivity, product quality, and manufacturing performance.
• Developing, optimizing, and implementing proteomics and metabolomics workflows to characterize cellular pathways, biological mechanisms, and molecular drivers of cell performance.
• Supporting the development of analytical platforms for cell line selection, characterization, and monitoring.
• Performing sample preparation, method development, and analysis for LC-MS/MS, mass spectrometry, proteomics, and metabolomics studies.
• Generating and analyzing Host Cell Protein (HCP) profiles to support cell line development and characterization.
• Supporting the development of high-throughput and automated analytical workflows to improve efficiency, reproducibility, and scalability.
• Developing and refining sample preparation, analytical methods, and experimental workflows for biological sample analysis.
• Investigating protein function, regulation, and interaction networks to identify potential cell engineering targets that improve cell productivity, titer, and product quality.
• Collaborating with upstream process development teams to address research questions related to cell culture performance, process optimization, and complex biologics modalities.
• Operating advanced analytical instrumentation and supporting technology transfer, validation, and implementation activities.
• Analyzing, interpreting, visualizing, and presenting experimental results using statistical and analytical approaches.
• Participating in experimental design discussions and technical problem-solving activities.
• Maintaining laboratory notebooks, technical documentation, and project records in accordance with established guidelines.
• Providing additional laboratory, analytical, and project support as needed.

Qualifications / Requirements

• Completion of Undergraduate Freshman year at an accredited University is required.
• Currently pursuing a Bachelor’s, Master’s or PhD degree in Biology, Chemistry, Analytical Chemistry, Biochemistry, Molecular Biology, Chemical, Biological, Biomedical Engineering, Pharmaceutical Sciences, or Related scientific disciplines.
• Have a cumulative GPA of 3.0 or higher, which is reflective of all college coursework.
• Strong analytical, quantitative, and problem-solving skills.
• Strong written, verbal, presentation, and interpersonal communication skills.
• Ability to balance multiple projects and priorities simultaneously.
• Ability to work independently while contributing effectively within a collaborative team environment.
• Demonstrated leadership, initiative, and scientific curiosity.
• Permanently authorized to work in the U.S., must not require sponsorship of an employment visa (e.g., H-1B or green card) at the time of application or in the future.
• Students currently on CPT, OPT, or STEM OPT usually requires future sponsorship for long term employment and do not meet the requirements for this program unless eligible for an alternative long-term status that does not require company sponsorship.
• If you are under 18 years of age, you (the candidate) may need to obtain the necessary working papers or other documentation required by state law to start the assignment, as well as get a parent’s consent for the background check.
• Technical Requirements:

• Experience with mass spectrometry and biological sample preparation.
• Strong analytical, quantitative, and scientific data interpretation skills.
• Ability to analyze, process, and interpret LC-MS/MS and other biological datasets.
• Familiarity with proteomics, metabolomics, protein characterization, and biological sample analysis.

Preferred Qualifications

• Experience or exposure in one or more of the following areas is preferred:
• Proteomics, Metabolomics & Mass Spectrometry: Experience and/or familiarity with metabolomics workflows and biological pathway analysis.
• Experience with proteomics, including sample preparation, LC-MS/MS data acquisition, processing, and interpretation.
• Experience with LC-MS-based analysis of biological samples.
• Experience with quantitative proteomics, functional proteomics, or protein characterization studies.
• Experience operating mass spectrometry instrumentation and supporting analytical method development.
• Knowledge of LC-MS methods, data processing, and biological data interpretation.
• Cell Line Engineering & Cell Culture: Familiarity with mammalian cell culture and CHO cell-based production systems.
• Interest or experience in cell line engineering, cell line development, and biologics manufacturing.
• Understanding of cellular pathways, metabolism, protein regulation, productivity (Qp), titer, and product quality attributes.
• Automation & High-Throughput Workflows: Familiarity with automating analytical assays and routine laboratory workflows.
• Experience supporting high-throughput analytical platforms and workflow optimization.
• Experience improving assay robustness, reproducibility, scalability, and throughput through automation.
• Laboratory & Research Experience: Protein characterization wet-lab experience.
• Experience designing, executing, and documenting biological or analytical experiments.
• Experience with sample preparation methods for proteomics, metabolomics, and protein characterization analyses.

Ineligibility for severance.

Johnson & Johnson is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, age, national origin, disability, protected veteran status or other characteristics protected by federal, state or local law. We actively seek qualified candidates who are protected veterans and individuals with disabilities as defined under VEVRAA and Section 503 of the Rehabilitation Act. Johnson & Johnson is committed to providing an interview process that is inclusive of our applicants’ needs. If you are an individual with a disability and would like to request an accommodation, please contact us via https://www.jnj.com/contact-us/careers or contact AskGS to be directed to your accommodation resource.

#LI-Onsite #TDSCo-OpSpring2027

Required Skills: Preferred Skills:

At Johnson & Johnson,we believe health is everything.

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