Supervisor, Quality Control Biology

Artiva Biotherapeutics; San Diego (CA); On-site; USD 110,000 - 135,000; Full time

Benefits offered by this job

Comprehensive benefits including Medical, Dental, and Vision

401(k) Retirement Plan

Paid Time Off (PTO)

Job summary

Artiva Biotherapeutics is looking for a Quality Control Supervisor in San Diego, California, to manage the QC Bio team and ensure compliant testing processes. The successful candidate will have over 8 years of cGMP experience, specifically in biotech settings, and will work with NK and CAR-NK products.

The role involves supervising testing, training staff, and maintaining high standards of quality control. Artiva offers a collaborative working environment and comprehensive benefits, including medical and retirement plans.

Qualifications

• 8 years of cGMP QC experience in a cell therapy/biotech setting.
• At least 1 year of Supervisory or team lead experience required.
• Experience with NK cell or CAR-modified cell therapy products preferred.

Responsibilities

• Supervise the QC Bio team and support QC biology testing.
• Perform routine cGMP release and stability testing.
• Lead training for the Bio team on analytical methods.

Skills

cGMP QC experience

Technical writing skills

Critical thinking

Cell therapy knowledge

Education

Bachelor’s degree in Biology, Biochemistry, or related field

Tools

ELISA

Flow Cytometers

Microsoft Word

Microsoft Excel

Job description

About Artiva:

We are a clinical‑stage biotechnology company focused on developing natural killer (NK) cell–based therapies. Our mission is to develop effective, safe, and accessible cell therapies for patients with devastating autoimmune diseases. We aim to develop therapies that patients and physicians can utilize in a community setting. Our lead product candidate, AlloNK, is a non‑genetically modified, cryopreserved NK cell therapy being evaluated in combination with B‑cell targeted monoclonal antibodies (mAbs). We believe the compelling cell‑killing properties of NK cells, when combined with mAbs for targeting, creates an opportunity to generate potentially transformative therapies.

For more information, visit www.artivabio.com.

Job Summary:

Artiva Biotherapeutics is seeking a skilled and motivated Quality Control Supervisor who will be reporting to the Senior Manager, Quality Control. This individual will supervise the Bio Team and support QC biology testing. The individual will additionally perform routine cGMP release and stability testing of Artiva’s products.

Duties/Responsibilities:

• Write and revise SOPs/Test methods that support Artiva’s cell therapy products.
• Operate and test ELISA, Flow Cytometers, automated cell counters, and other analytical instruments and equipment, as needed.
• Serve as primary QC Biology point of contact for cross‑functional teams including Manufacturing, QA, and Regulatory Affairs for release and investigation activities.
• Lead training and qualification of Bio team members on equipment use and biological test methods.
• Support activities for QC equipment IQ/OQ/PQs.
• Lead and perform routine cGMP release and stability testing of Artiva’s products; including biological tests, biochemistry, chemistry‑based tests as needed.
• Lead evaluation of QC systems and/or implementation of system improvements.
• Perform laboratory investigations and write reports for deviations.
• Ensure data integrity practices (ALCOA+ principles) are followed by the Bio team; support LIMS/ELN implementation and administration as applicable.
• Assist in laboratory investigations for Out of Specification results.
• Assist in biological method qualification and validation as needed.
• Perform periodic trending of QC testing data; identify adverse trends and initiate CAPAs as appropriate.
• Perform all work according to company policies, SOPs, and cGMP practices.
• Planning and scheduling for GMP in‑process and release testing.
• Reviewing biology data and investigating OOS and OOT results.
• Write technical QC protocols and reports as needed.
• Assist QC and AD team for analytical qualification and validation, as necessary.
• Develop an in‑depth understanding of NK and CAR‑NK products, testing, and safety.
• Maintain records and databases in accordance with procedures.

Qualifications:

• Bachelor’s degree (BS/BA) in Biology, Biochemistry, Immunology, or a related life science field required.
• Experience with NK cell or CAR‑modified cell therapy products preferred; familiarity with viability, cytotoxicity, identity, and potency assays for cell therapy products.
• Minimum 8 years of cGMP QC experience in a cell therapy/biotech/pharmaceutical setting is required.
• At least 1 year of Supervisory or team lead experience is required.
• Knowledge and experience in supporting cGMP deviations, OOS, etc.
• Basic knowledge of method transfers, qualifications, and validations; current industry practices; and strong experience with guidance interpretation and application.
• Excellent critical thinking and technical writing skills.
• Computer skills required to operate Microsoft Word, Project, Visio, and Excel programs.

In addition to a great culture, we offer:

• A beautiful facility
• An entrepreneurial, highly collaborative, and innovative environment
• Comprehensive benefits, including:
• Medical, Dental, and Vision
• Group Life Insurance
• Long Term Disability (LTD)
• 401(k) Retirement Plan
• Employee Assistance Program (EAP)
• Flexible Spending Account (FSA)
• Paid Time Off (PTO)
• Company paid holidays, including the year‑end holiday week
• Our recognition program, Bonus.ly, is where you can trade in points earned for things you want.

If all this speaks to you, come join us on our journey!

Base Salary: $110,000 - $135,000. Exact compensation may vary based on level, skills and experience.