Summer Intern: AI-Driven QSP Modeling for CVRM

1000 Genentech, Inc.; South San Francisco (CA); Presencial; USD 59.000 - 84.000; Jornada completa

Ventajas ofrecidas por este puesto de trabajo

Stipend

Paid holiday time off

Descripción de la vacante

Genentech, a member of the Roche group, seeks a PhD student to join the Modeling and Simulation group for QSP modeling in CVRM diseases, including obesity, using MATLAB/SimBiology. This 12-week, full-time internship is on-site in South San Francisco.

The intern will develop and calibrate QSP models, validate against data, and present results at poster sessions and in a written report. A stipend is provided and holiday time off is included.

Formación

• Pursuing a PhD (enrolled student).
• Experience building and analyzing ODE models of biological or pharmacological systems.
• Proficiency in MATLAB (SimBiology preferred), R, or Python.

Responsabilidades

• Develop, extend, or integrate mechanistic QSP models of CVRM physiology and disease in MATLAB/SimBiology.
• Represent drug pharmacology and its links to physiological and clinical outcomes in these models.
• Calibrate and validate models against published preclinical and clinical data.
• Use simulation, sensitivity analysis and virtual populations to address questions from drug development teams.
• Leverage AI coding tools to accelerate model development, testing and documentation, with rigorous verification of results.
• Present results to project teams and the department, at the intern poster session, and in a written report.

Conocimientos

ODE modeling

Parameter estimation

Data interpretation

MATLAB or Python

R

Educación

Pursuing a PhD (enrolled student)

Herramientas

MATLAB (SimBiology)

Python

R

Git

Descripción del empleo

Genentech, a member of the Roche group, seeks a PhD student to join the Modeling and Simulation group for QSP modeling in CVRM diseases, including obesity, using MATLAB/SimBiology. This 12-week, full-time internship is on-site in South San Francisco.

The intern will develop and calibrate QSP models, validate against data, and present results at poster sessions and in a written report. A stipend is provided and holiday time off is included.