Summer 2027 Intern - Post-Doc - Biomarker

Charles River Laboratories; Mattawan (MI); On-site; USD 38,000 - 53,000; Full time

Benefits offered by this job

Bonus incentives

401K

Paid time off

Stock purchase program

Health coverage

Wellbeing support

Work life balance

Job summary

Charles River Laboratories offers a Doctoral/Post-doctoral Internship to gain hands-on experience in large molecule drug development using ligand binding assays (LBA), including ELISA, PK and ADA/NAb measurements.

You will work with platforms such as MSD, Luminex and Gyrolab, perform procedures per SOPs, collaborate across teams, and assist with method development and validation under supervision during a 12-week program.

Qualifications

• PhD or doctoral/postdoctoral equivalence recently completed or nearing completion.
• Program duration of 12 weeks.
• Strong communication skills across levels.
• Basic PC office skills; learn validated systems.
• Willingness to work extended hours, including evenings and weekends.
• Ability to meet tight time constraints.

Responsibilities

• Perform and document procedures following SOPs and regulatory standards.
• Collaborate across operations to meet timelines and generate quality data.
• Assist with drug development projects under supervision.
• Support laboratory investigations and troubleshoot quality issues.
• Develop quantitative/qualitative methods within one area with minimal oversight.
• Communicate findings to management to minimize study impact.

Skills

Verbal and written communication

Microsoft Office familiarity

Team collaboration

Time management

Extended hours

Time constraints

Education

PhD in relevant field

Job description

For 75 years, Charles River employees have worked together to assist in the discovery, development and safe manufacture of new drug therapies. When you join our family, you will have a significant impact on the health and well-being of people across the globe. Whether your background is in life sciences, finance, IT, sales or another area, your skills will play an important role in the work we perform. In return, we'll help you build a career that you can feel passionate about.

Job Overview

Doctoral/Post-doctoral Internship essential Functions (The fundamental Duties & Responsibilities of the role (products and services provided/results accomplished) include, but are not limited to, those listed:

• Efficiently perform and document all procedures, materials and results in compliance with applicable regulatory standards as applicable (protocols, methods, SOPs, etc.)

• Actively communicate and collaborate across operational areas in order to adhere to timelines and produce quality data

• Assist and/or execute assigned project with oversight to gain first-hand experience with industry drug development

• Assist with the completion of laboratory investigations, assay troubleshooting, quality observations, and problem solving of technical and/or regulatory issues with oversight, as needed

• Effectively develop quantitative/qualitative methods/procedures with limited complexity/scope in one operational area with minimal oversight

• Develop critical thinking, troubleshooting and time management skills aligned with needs of operational areas

• Demonstrate effective communication skills through informal discussions with peers, supervisor, and team

• Develop ability to recognize method and/or data issues and communicate them to management to minimize study impact with minimal oversight

• Develop knowledge of regulatory and GXP requirements, industry standards and company SOPs within one operational area

• Performs all other related duties as assigned

The pay range for this position is $33.00 per hour. Please note that salaries vary within the range based on factors including, but not limited to, experience, skills, education, certifications, and location

Position is open to anyone, regardless of age, who meets the educational and experience requirements as posted.

Must be eligible to work in the US without requiring a sponsor visa.

Job Description

The BioA LBA support large molecule drug development using ligand binding assays (LBA), such as enzyme-linked immunosorbent assay (ELISA), to measure large molecules and their immune responses. The main types of assays include Pharmacokinetic (PK) assays to measure drug and Immunogenicity assay to measure anti-drug antibodies (ADA) and neutralizing antibodies (NAb). An array of platforms are used to support these assays that include spectrophotometer, Meso Scale Discovery (MSD), Luminex and Gyrolab. Utilizing these platforms/assays, the teams are responsible for the method development, validation and routine sample analysis in both the regulated and non-regulated space of non-clinical and clinical studies.

Job Qualifications

Qualifications (Knowledge, Experience, Skills and Abilities required to accomplish the essential functions) include but are not limited to:

• Doctorate degree (PhD) recently obtained looking to expand skills to industry drug development. PhD students in the last year of their thesis work are eligible to apply as well.

• Program duration for 12 weeks.

• Ability to communicate verbally and in writing at all levels inside and outside the organization.

• Basic familiarity with Microsoft Office Suite.

• Computer skills, commensurate with Essential Functions, including the ability to learn a validated system.

• Ability to work extended hours beyond normal work schedule to include, but not limited to evenings, weekends, extended shifts, and/or extra shifts; sometimes on short notice.

• Ability to work under specific time constraints.

Education

Advanced degree or certification required

Physical Requirements

About Safety Assessment

Charles River is committed to helping our partners expedite their preclinical drug development with exceptional safety assessment services, state-of-the-art facilities and expert regulatory guidance. From individual specialty toxicology and IND enabling studies to tailored packages and total laboratory support, our deeply experienced team can design and execute programs that anticipate challenges and avoid roadblocks for a smooth, efficient journey to market. Each year approximately 300 investigational new drug (IND) programs are conducted in our Safety Assessment facilities.

About Charles River

Charles River is an early-stage contract research organization (CRO). We have built upon our foundation of laboratory animal medicine and science to develop a diverse portfolio of discovery and safety assessment services, both Good Laboratory Practice (GLP) and non-GLP, to support clients from target identification through preclinical development. Charles River also provides a suite of products and services to support our clients' clinical laboratory testing needs and manufacturing activities. Utilizing this broad portfolio of products and services enables our clients to create a more flexible drug development model, which reduces their costs, enhances their productivity and effectiveness to increase speed to market.

With over 20,000 employees within 110 facilities in over 20 countries around the globe, we are strategically positioned to coordinate worldwide resources and apply multidisciplinary perspectives in resolving our client's unique challenges. Our client base includes global pharmaceutical companies, biotechnology companies, government agencies and hospitals and academic institutions around the world.

At Charles River, we are passionate about our role in improving the quality of people's lives. Our mission, our excellent science and our strong sense of purpose guide us in all that we do, and we approach each day with the knowledge that our work helps to improve the health and well-being of many across the globe. We have proudly worked on 80% of the drugs approved by the U.S. Food and Drug Administration (FDA) in the past five years.

We're committed to providing benefits that elevate your quality of life. Based on your position these may include: bonus/incentives based on performance, 401K, paid time off, stock purchase program, Health and wellness coverage, employee and family wellbeing support programs, and work life balance flexibility.

Equal Employment Opportunity

Charles River is an equal opportunity employer and is committed to providing equal employment opportunities for all qualified applicants and employees without regard to race, color, sex, religion, national origin, ancestry, age, mental or physical disability, family status, pregnancy, military or veteran status, or any other characteristic protected by federal, state, or local laws.

It is unlawful in some states (including Massachusetts) to require or administer a lie detector test as a condition of employment or continued employment. An employer who violates this law shall be subject to criminal penalties and civil liability.

If you are interested in applying to Charles River Laboratories and need special assistance or an accommodation due to a disability to complete any forms or to otherwise participate in the resume submission process, please contact a member of our Human Resources team by sending an e-mail message to [e-mail]. This contact is for accommodation requests for individuals with disabilities only and cannot be used to inquire about the status of applications.

For more information, please visit www.criver.com.