Staff+ Software Engineer, Claude Science

Anthropic

San Francisco (CA)

Hybrid

USD 405,000 - 485,000

Full time

17 hours ago
Be an early applicant
Application generator

A complete application in a minute — tailored resume and cover letter, ready to send.

Get past ATS filters

Benefits offered by this job

Equity donation matching
Generous vacation and parental leave
Flexible working hours
Lovely office space

Job summary

Anthropic in San Francisco is seeking a seasoned Staff Software Engineer to shape the Claude Science product and architecture. You will lead end-to-end development with researchers and product teams, translating complex scientific needs into scalable software systems.

Applicants should have 8+ years in software engineering, prior staff-level experience, and a track record of delivering AI-enabled products. The role offers a hybrid office policy in SF and competitive compensation.

Qualifications

  • 8+ years of software engineering experience.
  • Staff or equivalent technical leadership experience.
  • Built AI products and know how to turn model capabilities into applications.
  • Able to translate learnings from scientists into engineering priorities.

Responsibilities

  • Ship fast against a roadmap you help shape, in a category with no defined precedent.
  • Interface directly with scientists and research teams to translate needs into engineering priorities.
  • Partner with product and design to turn scientists' workflows into shipped products.
  • Work with research to improve model evaluation, failure modes, and real-world integration.

Skills

8+ years software engineering
Staff or leadership experience
AI product development
cross-team collaboration
work with researchers

Education

Bachelor’s degree

Job description

About Anthropic

Anthropic’s mission is to create reliable, interpretable, and steerable AI systems. We want AI to be safe and beneficial for our users and for society as a whole. Our team is a quickly growing group of committed researchers, engineers, policy experts, and business leaders working together to build beneficial AI systems.

About Anthropic

Anthropic’s mission is to create reliable, interpretable, and steerable AI systems. We want AI to be safe and beneficial for our users and for society as a whole. Our team is a quickly growing group of committed researchers, engineers, policy experts, and business leaders working together to build beneficial AI systems.

About The Role

Anthropic’s mission is to create reliable, interpretable, and steerable AI systems. We believe powerful AI can compress a century of scientific progress into a decade. Claude Science is a big part of building toward that future. Claude Science is an AI workbench that gives researchers a single environment for work that today spans dozens of disconnected tools — literature, specialized databases, scientific computing, analysis, and publication-ready outputs. Claude Science already renders protein structures, genome tracks, and chemical structures natively, and coordinates multi-agent workflows with built-in review for citation and calculation errors — and we’re just getting started. Much of this is being built 0→1 right now: you’ll shape both the product and the architecture in a category no one has defined yet. You'll be a technical leader who thinks holistically about the end-to-end researcher experience, partners directly with our internal research team to push model capabilities into production, and carries real ownership over what we ship next. Our north star is accelerating scientific progress — across biology, chemistry, physics, and beyond — from early discovery through real-world application, by an order of magnitude. This work supports programs like Anthropic’s AI for Science Program and our rare disease research grants.

What you'll do
  • Ship fast against a roadmap you help shape: this is a product in a category no one has defined yet, and the highest-leverage problems are still unclaimed
  • Interface directly with working scientists — academic labs, industry R&D teams, and research institutes — during key conversations, translating what you learn into engineering priorities
  • Partner with product and design to turn how scientists actually work — from hypothesis to analysis to publication — into shipped product
  • Work closely with research to make the models better at science: shaping evals, surfacing failure modes, and feeding what users hit in the real world back into model development
You may be a good fit if you
  • Have 8+ years of software engineering experience, ideally with 2+ years at a Staff or equivalent technical leadership level
  • Have built products from 0 to 1 in fast-moving environments, and can set technical direction with limited precedent to lean on
  • Have built AI products and know what it takes to turn model capabilities into applications people actually use
  • Are comfortable working directly with technical domain experts and translating what you learn
  • Drive cross-team alignment to ship impactful work, with influence over authority
Strong candidates may also have
  • Background in chemistry, biology, physics, or another science
  • Experience working with research teams to improve domain-specific model capabilities, including evaluation frameworks

The annual compensation range for this role is listed below.

Annual Salary

$405,000—$485,000 USD

Logistics

Minimum education: Bachelor’s degree or an equivalent combination of education, training, and/or experience

Required field of study: A field relevant to the role as demonstrated through coursework, training, or professional experience

Minimum years of experience: Years of experience required will correlate with the internal job level requirements for the position

Location-based hybrid policy: Currently, we expect all staff to be in one of our offices at least 25% of the time. However, some roles may require more time in our offices.

Visa sponsorship: We do sponsor visas! However, we aren't able to successfully sponsor visas for every role and every candidate. But if we make you an offer, we will make every reasonable effort to get you a visa, and we retain an immigration lawyer to help with this.

We encourage you to apply even if you do not believe you meet every single qualification. Not all strong candidates will meet every single qualification as listed. Research shows that people who identify as being from underrepresented groups are more prone to experiencing imposter syndrome and doubting the strength of their candidacy, so we urge you not to exclude yourself prematurely and to submit an application if you're interested in this work. We think AI systems like the ones we're building have enormous social and ethical implications. We think this makes representation even more important, and we strive to include a range of diverse perspectives on our team.

Your safety matters to us.

To protect yourself from potential scams, remember that Anthropic recruiters only contact you from @anthropic.com email addresses. In some cases, we may partner with vetted recruiting agencies who will identify themselves as working on behalf of Anthropic. Be cautious of emails from other domains. Legitimate Anthropic recruiters will never ask for money, fees, or banking information before your first day. If you're ever unsure about a communication, don't click any links—visit anthropic.com/careers directly for confirmed position openings.

How We're Different

We believe that the highest-impact AI research will be big science. At Anthropic we work as a single cohesive team on just a few large-scale research efforts. And we value impact — advancing our long-term goals of steerable, trustworthy AI — rather than work on smaller and more specific puzzles. We view AI research as an empirical science, which has as much in common with physics and biology as with traditional efforts in computer science. We're an extremely collaborative group, and we host frequent research discussions to ensure that we are pursuing the highest-impact work at any given time. As such, we greatly value communication skills.

Come work with us!

Anthropic is a public benefit corporation headquartered in San Francisco. We offer competitive compensation and benefits, optional equity donation matching, generous vacation and parental leave, flexible working hours, and a lovely office space in which to collaborate with colleagues. Guidance on Candidates' AI Usage: Learn about our policy for using AI in our application process.

Get your free, confidential resume review.
or drag and drop your file here.
Similar jobs

Similar jobs worth comparing

Product Manager, Claude Science
Product Manager, Claude Science

Anthropic • San Francisco (CA), New York (NY), Seattle (WA)

On-site
USD 230,000 - 350,000
Competitive compensation
Equity donation matching
Generous vacation and parental leave
+2
Staff+ Software Engineer, Claude Science
Staff+ Software Engineer, Claude Science

AI Chopping Block • San Francisco (CA), Northern (KY)

Hybrid
USD 405,000 - 485,000
Staff+ Software Engineer, Claude Science
Staff+ Software Engineer, Claude Science

Candidate • San Francisco (CA), Northern (KY)

Hybrid
USD 405,000 - 485,000
Competitive compensation
Equity donation matching
Generous vacation and parental leave
+2
Partnership Manager, AI for Science
Partnership Manager, AI for Science

Anthropic • San Francisco (CA)

Hybrid
USD 170,000 - 215,000
Staff+ Software Engineer, Claude Science San Francisco, CA
Staff+ Software Engineer, Claude Science San Francisco, CA

Anthropic Limited • San Francisco (CA), Northern (KY)

Hybrid
USD 405,000 - 485,000
Applied AI Engineer, Beneficial Deployments (Life Sciences)
Applied AI Engineer, Beneficial Deployments (Life Sciences)

AI Chopping Block • San Francisco (CA), Northern (KY)

Hybrid
USD 280,000 - 320,000
Competitive compensation
Equity donation matching
Generous vacation and parental leave
+2
Staff Software Engineer, Front-End
Staff Software Engineer, Front-End

Menlo Ventures • San Francisco (CA)

Hybrid
USD 243,000 - 405,000
Competitive compensation
Benefits
Equity donation matching
+4
Software Engineer, Research Tools
Software Engineer, Research Tools

Anthropic • San Francisco (CA)

Hybrid
USD 300,000 - 405,000
Competitive compensation
Equity donation matching
Generous vacation and parental leave
+1
Staff+ Software Engineer, Product Sandboxing
Staff+ Software Engineer, Product Sandboxing

Anthropic • Seattle (WA)

Hybrid
USD 405,000 - 485,000
Data Scientist, Product
Data Scientist, Product

Anthropic • New York (NY), San Francisco (CA), Seattle (WA)

On-site
USD 285,000 - 380,000