Staff CT Imaging Systems Engineer – Cardiac AI

Heartflow; San Francisco (CA); On-site; USD 190,000 - 250,000; Full time

Job summary

Heartflow is seeking a Staff Systems Engineer with deep CT imaging expertise to lead system architecture and verification across EID-CT and PCCT. You will own requirements, validation strategies, and cross-functional collaboration to ensure consistent, accurate CT outputs for Heartflow analyses that support early diagnoses and patient care.

You will partner with Engineering, Clinical Research, Regulatory, and Quality to navigate scanner differences, kernels, and techniques, driving design

Qualifications

• 10+ years of Systems Engineering experience in medical devices or regulated imaging products.
• Direct experience with CT acquisition and reconstruction across EID-CT and PCCT.
• Experience developing FDA-regulated SaMD and regulatory submissions.

Responsibilities

• Own the strategy and system architecture for optimizing Heartflow product outputs across EID-CT and PCCT, spanning scanners, detectors, reconstruction kernels, and imaging techniques.
• Define the optimal and acceptable ranges of CT scanner and recon settings that result in high quality Heartflow results.
• Partner with cross functional groups on new initiatives (new products, features or improvement in performance) that leverage new CT technologies.
• Collaborate with Clinical Research to design data campaigns that quantify imaging performance and variance across machines, techniques, and populations.
• Monitor the CT landscape across OEMs; track new market entrants and any significant changes that could impact Heartflow products, and manage the details required to support the change(s).
• Represent Systems Engineering in design reviews, program planning, and cross-functional decision-making, and serve as the CT subject matter expert in regulatory submissions and audits.
• Define and maintain system requirements with full traceability from user needs through verification, consistent with design controls.
• Translate clinical and product goals into testable, unambiguous requirements in alignment with cross-functional stakeholders.
• Promote Systems Engineering best practices across teams, and mentor Systems Engineers as the team scales.

Skills

CT imaging

Systems engineering

Statistical analysis

Regulatory submissions

Regulatory knowledge

Communication

Education

B.S./M.S. in Systems Engineering or related

Ph.D. preferred

Tools

DICOM

PACS integration

Job description

Heartflow is seeking a Staff Systems Engineer with deep CT imaging expertise to lead system architecture and verification across EID-CT and PCCT. You will own requirements, validation strategies, and cross-functional collaboration to ensure consistent, accurate CT outputs for Heartflow analyses that support early diagnoses and patient care.

You will partner with Engineering, Clinical Research, Regulatory, and Quality to navigate scanner differences, kernels, and techniques, driving design