Sr. Technical Program Manager, Infrastructure Engineering

BioSpace; Cambridge (MA); On-site; USD 146,000 - 234,000; Full time

Benefits offered by this job

Healthcare

Well-being resources

Family planning benefits

Paid time off

Savings and investments

Location-specific perks

Job summary

Moderna is seeking a Senior Technical Program Manager to lead program management for infrastructure rationalization and AI-readiness initiatives globally. You will coordinate cloud and on-prem environments, manage vendors and risks, and drive standardized, secure foundations for AI workloads.

You will partner with Cloud, Systems, and AI Engineering, shaping governance, KPIs, and cost optimization while advancing security and infrastructure excellence.

Qualifications

• 8+ years of program management experience, preferably in infrastructure engineering.
• Technical depth, stakeholder and vendor management skills.
• Background in infrastructure engineering with ITSM understanding.
• Experience running cross-functional, global programs with multiple workstreams.
• Ability to scope and drive complex programs in a structured, data-driven way.
• Strong listening skills and ability to solicit constructive feedback.
• Proven ability to influence in matrixed environments without direct authority.

Responsibilities

• Program management using structured, data-driven, risk-based approaches.
• Kick off and manage multiple high-visibility workstreams with ownership and strong processes.
• Develop templates and processes or adapt existing ones.
• Manage vendors, schedule, scope, and cost.
• Measure success and risks with data; propose remediation strategies.
• Maintain stakeholder relationships and drive outcomes across teams.
• Communicate clearly and timely; support secure, AI-ready infrastructure.
• Collaborate with Cloud, Systems, AI Eng, and other orgs to drive improvements.

Skills

Program management

Infrastructure

Vendor management

Risk management

Cross-functional leadership

Data-driven decision making

ITSM

Tools

AWS

Azure

Kubernetes

GPUs

ITIL

Job description

The Role

Moderna is seeking a Senior Technical Program Manager (TPM) to drive project and program management of infrastructure (cloud and on-prem) rationalization and AI-readiness initiatives at Moderna globally. We're looking for someone with a high level of integrity and personal accountability, strong interpersonal skills, and infrastructure technology domain expertise.

Here's What You'll Do

• Program Management – take a structured, data-driven, and risk-based approach to program scoping, execution, and reporting
• Kick off and successfully manage multiple, simultaneous, complex, high visibility workstreams with full ownership, effective collaboration, and good process
• Build processes, templates, and structure, or leverage existing ones as appropriate
• Manage vendors, schedule, scope, and cost
• Measure program success (or lack thereof) and risks using data and facts
• Provide balanced risk remediation strategies and recommendations and drive risk mitigation
• Develop and maintain close stakeholder relationships and build influence to drive the appropriate outcomes across Moderna
• Provide clear, accurate, consistent, and timely communications
• Advance good infrastructure and security practices and culture
• Partner collaboration work with Cloud Engineering, Systems Engineering, and AI Engineering, as well as Network Engineering, Identity and Access Management, Builder Tools & Platforms, IT, Cybersecurity, software engineering, and business stakeholders to manage and drive improvement projects in a structured and predictable manner
• Manage multiple initiatives:
  1. Cloud modernization
  2. Rationalize infrastructure platforms, tooling, and service models that underpin AI workloads.
• Identify and eliminate redundant, unsupported, or non-scalable infrastructure patterns that impede AI adoption.
• Enable standardized, secure, and supportable AI-ready infrastructure foundations that accelerate time-to-value while managing cost and risk.
• Ensure infrastructure rationalization aligns with AI governance, data protection, and compliance requirements.
• Define and track KPIs related to platform consolidation, cost optimization, risk reduction, and AI enablement readiness.
• Lead and drive infrastructure service management improvements and process optimization initiatives, including infrastructure patch and vulnerability management.
• Actively contribute to creating a more inclusive culture and environment at Moderna; endorse, create, and maintain anti-racist policies and processes

Here's What You'll Need (Minimum Qualifications)

• 8+ years of program management experience, preferably in infrastructure engineering
• Demonstrated technical depth, problem-solving capabilities, and stakeholder and vendor management skills
• Technical background in infrastructure engineering, with a strong understanding of ITSM
• Experience in running programs within a cross-functional, global team of mixed engineering, architecture, and operations.
• Ability to successfully scope and drive complex and multi-workstream programs in a structured, risk-considerate, data-driven fashion
• Strong listener with the ability to deeply understand, ask the right questions, and proactively pursue constructive feedback
• Proven ability to operate in highly matrixed environments and influence without direct authority.

Here's What You'll Bring to the Table (Preferred Qualifications)

• Strong understanding of cloud platforms (AWS, Azure)
• Familiarity with infrastructure concepts: compute, storage, networking, containers, Kubernetes
• Working knowledge of AI/ML infrastructure needs (GPUs, distributed training, data pipelines, MLOps)
• Influential, inclusive, and trusted partner compassionate to the needs and situations of all your stakeholders
• Deep familiarity with ITSM frameworks (e.g., ITIL)
• Experience driving structured, process-driven infrastructure transformation initiatives.
• Knowledge of security and compliance standards relevant to infrastructure operations.
• Embrace a culture of continuous service improvement and service excellence
• A desire to make an impact as part of a high-growth, transformational company
• Experience with GxP environments and regulatory requirements

Pay & Benefits

At Moderna, we believe that when you feel your best, you can do your best work. That's why our benefits and well-being resources are designed to support you at work, at home, and everywhere in between.

• Competitive healthcare, plus voluntary benefit programs to support your unique needs
• A holistic approach to well-being, with access to fitness, mindfulness, and mental health support
• Family planning benefits, including fertility, adoption, and surrogacy support
• Generous paid time off, including vacation, volunteer days, sabbatical, global recharge days, and a discretionary year-end shutdown
• Savings and investments to help you plan for the future
• Location-specific perks and extras

The salary range for this role is $145,900.00 - $234,200.00. This is the lowest to highest salary we in good faith believe we would pay for this role at the time of this posting. An individual’s position within the salary range will be based on several factors including, but not limited to, specific competencies, relevant education, qualifications, certifications, experience, skills, performance, and business or organizational needs. The successful candidate may be eligible for an annual discretionary bonus, other incentive compensation, or equity award, subject to company plan eligibility criteria and individual performance.

About Moderna

Since our founding in 2010, we have aspired to build the leading mRNA technology platform, the infrastructure to reimagine how medicines are created and delivered, and a world-class team. We believe in giving our people a platform to change medicine and an opportunity to change the world.

By living our mission, values, and mindsets every day, our people are the driving force behind our scientific progress and our culture. Together, we are creating a culture of belonging and building an organization that cares deeply for our patients, our employees, the environment, and our communities.

We are proud to have been recognized as a Science Magazine Top Biopharma Employer, a Fast Company Best Workplace for Innovators, and a Great Place to Work in the U.S.

If you want to make a difference and join a team that is changing the future of medicine, we invite you to visit modernatx.com/careers to learn more about our current opportunities.

Our Working Model

As we build our company, we have always believed an in-person culture is critical to our success. Moderna champions the significant benefits of in-office collaboration by embracing a 70/30 work model. This 70% in-office structure helps to foster a culture rich in innovation, teamwork, and direct mentorship. Join us in shaping a world where every interaction is an opportunity to learn, contribute, and make a meaningful impact.

Moderna is a smoke-free, alcohol-free, and drug-free work environment.

Equal Opportunities

Moderna is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person’s race, color, sex, gender identity or expression, age, religion, national origin, ancestry or citizenship, ethnicity, disability, military or protected veteran status, genetic information, sexual orientation, marital or familial status, or any other personal characteristic protected under applicable law. Moderna is a place where everyone can grow.

Accommodations

We're focused on attracting, retaining, developing, and advancing our employees. By cultivating a workplace that values diverse experiences, backgrounds, and ideas, we create an environment where every employee can contribute their best.

Moderna is committed to offering reasonable accommodations to qualified job applicants with disabilities. Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should contact the Accommodations team at [e-mail].

Export Control Notice

This position may involve access to technology or data that is subject to U.S. export control laws, including the Export Administration Regulations (EAR). As such, employment is contingent upon the applicant’s ability to access export-controlled information in accordance with U.S. law. Due to the nature of the work and regulatory requirements, only individuals who qualify as U.S. persons (citizens, permanent residents, asylees, or refugees) are eligible for this position. For this role Moderna is unable to sponsor non-U.S. persons to apply for an export control license.