Sr Systems Engineer

Twist Bioscience; Portland (OR); On-site; USD 120,000 - 180,000; Full time

Job summary

Twist Bioscience is seeking a Senior Systems Engineer to join our team onsite in Wilsonville, OR. You will lead development, validation, and integration of automated laboratory instrumentation and bioprocess technologies, bridging hardware, software, and biology to drive operational excellence and product quality under ISO 13485.

You will design automated workflows, write integration scripts, and connect robotic systems with enterprise LIMS to support scalable synthesis and data management.

Qualifications

• PhD/MS with 3 years (BS with 5 years) in Biomedical/Engineering.
• Experience developing automated instrumentation for bioprocesses.
• Experience with DoE for testing and troubleshooting of processes.
• Experience designing/writing scripts (C#, Python) for lab automation systems.
• Experience with sample tracking software and interfaces between robotic instruments and LIMS (MES/Maestro, Twist build).
• Strong data analysis and computational skills.
• Hands-on skills to assemble and maintain hardware.

Responsibilities

• Develop, validate, and release new processes to improve cost-effectiveness and product quality.
• Develop and test protocols, scripts, and systems to automate bioprocesses.
• Operate and maintain laboratory automation instruments and cross-integration systems.
• Collaborate with multi-disciplinary teams to troubleshoot equipment and systems.
• Prepare documentation, knowledge transfer, and training activities.
• Follow regulatory and ISO 13485 requirements.

Skills

C# scripting

Python scripting

Lab automation

Bioprocess instrumentation

LIMS integration

Data analysis

Hardware assembly

Education

Ph.D. in Biomedical Engineering

MS in Biomedical/related field

BS in engineering

Tools

DoE software

Control software

Laboratory instruments

Job description

Sr. Systems Engineer (Onsite in Wilsonville, OR)

Summary

We are seeking a Senior Systems Engineer to join our team in Portland, OR (PDX). In this role, you will lead the development, validation, and integration of cutting-edge automated laboratory instrumentation and bioprocess technologies. Working at the intersection of hardware, software, and biology, you will design automated workflows, write custom integration scripts, and connect robotic systems with enterprise LIMS infrastructure to drive operational excellence and product quality under ISO 13485 standards.

What You’ll Do

• Develop, validate, and release new processes and technologies to achieve cost-effectiveness and improved product quality
• Develop and test protocols, scripts, and systems to automate certain bioprocesses
• Operation and maintenance of a range of scientific instruments and tools with a focus on laboratory automation systems and cross-integration systems
• Collaborate with multi-disciplinary teams in troubleshooting and resolving issues concerning equipment and systems
• Prepare and participate in documentation, knowledge transfer, and training activities
• Follow regulatory and ISO 13485 requirements

What You’ll Bring

• Ph.D. or MS with 3 years, BS with 5 years of related experience in Biomedical Engineering, Chemical Engineering, Mechanical/Electrical Engineering, or related field
• Experience in developing automated instrumentation for bioprocesses
• Experience with DoE for testing and troubleshooting of certain processes
• Experience in designing and writing scripts (C#, Python, etc) using control software or dynamic scheduling software native to laboratory automation systems and cross-integration systems
• Experience with sample tracking software and developed interfaces between robotic instrumentation and LIMS systems (MES/Maestro, Twist build)
• Excellent scientific computation and data analysis capabilities
• Hands-on skills to assemble and maintain hardware
• Experience with biological instrumentation for liquid transfer, PCR, cell-based cloning, DNA extraction, and purification is desirable
• Working collaboratively with other functional groups
• Excellent communication and writing skills, and ability to work in a fast-paced team environment

About Twist Bioscience

Twist Bioscience synthesizes genes from scratch, known as “writing” DNA. Just as children learn to both read and write, the next phase of development for the genomics revolution is the ability to write DNA.

At Twist Bioscience, we work in service of people who are changing the world for the better. In fields such as health care, agriculture, industrial chemicals and data storage, our unique silicon-based DNA Synthesis Platform provides precision at a scale that is otherwise unavailable to our customers.

Twist Bioscience Corporation is an Equal Opportunity Employer. Twist Bioscience Corporation provides equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, age, disability, genetic characteristics, or any other category protected by law.

Apply for this job

*

indicates a required field

First Name *

Last Name *

Preferred First Name

Email *

Phone

Country *

Phone *

Location (City) *

Resume/CV *

Enter manually

Accepted file types: pdf, doc, docx, txt, rtf

Enter manually

Accepted file types: pdf, doc, docx, txt, rtf

LinkedIn Profile

Website

Will you now or at any point in the future require employment sponsorship to work for Twist Bioscience? * Select...

Voluntary Self-Identification

For government reporting purposes, we ask candidates to respond to the below self-identification survey.Completion of the form is entirely voluntary. Whatever your decision, it will not be considered in the hiringprocess or thereafter. Any information that you do provide will be recorded and maintained in aconfidential file.

As set forth in Twist Bioscience’s Equal Employment Opportunity policy,we do not discriminate on the basis of any protected group status under any applicable law.

If you believe you belong to any of the categories of protected veterans listed below, please indicate by making the appropriate selection.As a government contractor subject to the Vietnam Era Veterans Readjustment Assistance Act (VEVRAA), we request this information in order to measurethe effectiveness of the outreach and positive recruitment efforts we undertake pursuant to VEVRAA. Classification of protected categoriesis as follows:

A "disabled veteran" is one of the following: a veteran of the U.S. military, ground, naval or air service who is entitled to compensation (or who but for the receipt of military retired pay would be entitled to compensation) under laws administered by the Secretary of Veterans Affairs; or a person who was discharged or released from active duty because of a service-connected disability.

A "recently separated veteran" means any veteran during the three-year period beginning on the date of such veteran's discharge or release from active duty in the U.S. military, ground, naval, or air service.

An "active duty wartime or campaign badge veteran" means a veteran who served on active duty in the U.S. military, ground, naval or air service during a war, or in a campaign or expedition for which a campaign badge has been authorized under the laws administered by the Department of Defense.

An "Armed forces service medal veteran" means a veteran who, while serving on active duty in the U.S. military, ground, naval or air service, participated in a United States military operation for which an Armed Forces service medal was awarded pursuant to Executive Order 12985.

Select...

Voluntary Self-Identification of Disability

Form CC-305

Page 1 of 1

OMB Control Number 1250-0005

Expires 07/31/2029

Voluntary Self-Identification of Disability

Form CC-305 Page 1 of 1 OMB Control Number 1250-0005 Expires 07/31/2029
Why are you being asked to complete this form?

We are a federal contractor or subcontractor. The law requires us to provide equal employment opportunity to qualified people with disabilities. We have a goal of having at least 7% of our workers as people with disabilities. The law says we must measure our progress towards this goal. To do this, we must ask applicants and employees if they have a disability or have ever had one. People can become disabled, so we need to ask this question at least every five years.

Completing this form is voluntary, and we hope that you will choose to do so. Your answer is confidential. No one who makes hiring decisions will see it. Your decision to complete the form and your answer will not harm you in any way. If you want to learn more about the law or this form, visit the U.S. Department of Labor’s Office of Federal Contract Compliance Programs (OFCCP) website at www.dol.gov/ofccp .

How do you know if you have a disability?

A disability is a condition that substantially limits one or more of your “major life activities.” If you have or have ever had such a condition, you are a person with a disability. Disabilities include, but are not limited to:

• Alcohol or other substance use disorder (not currently using drugs illegally)
• Autoimmune disorder, for example, lupus, fibromyalgia, rheumatoid arthritis, HIV/AIDS
• Blind or low vision
• Cancer (past or present)
• Cardiovascular or heart disease
• Celiac disease
• Cerebral palsy
• Deaf or serious difficulty hearing
• Diabetes
• Disfigurement, for example, disfigurement caused by burns, wounds, accidents, or congenital disorders
• Epilepsy or other seizure disorder
• Gastrointestinal disorders, for example, Crohn's Disease, irritable bowel syndrome
• Intellectual or developmental disability
• Mental health conditions, for example, depression, bipolar disorder, anxiety disorder, schizophrenia, PTSD
• Missing limbs or partially missing limbs
• Mobility impairment, benefiting from the use of a wheelchair, scooter, walker, leg brace(s) and/or other supports
• Nervous system condition, for example, migraine headaches, Parkinson’s disease, multiple sclerosis (MS)
• Neurodivergence, for example, attention-deficit/hyperactivity disorder (ADHD), autism spectrum disorder, dyslexia, dyspraxia, other learning disabilities
• Partial or complete paralysis (any cause)
• Pulmonary or respiratory conditions, for example, tuberculosis, asthma, emphysema
• Short stature (dwarfism)
• Traumatic brain injury

Disability Status Select...

PUBLIC BURDEN STATEMENT: According to the Paperwork Reduction Act of 1995 no persons are required to respond to a collection of information unless such collection displays a valid OMB control number. This survey should take about 5 minutes to complete.