Sr. Site Contract Lead

Syneos Health; United States; Remote; USD 68,000 - 115,000; Full time

Benefits offered by this job

Company car or car allowance

Health benefits (medical, dental, and视

Company match 401k

Employee Stock Purchase Plan

Bonuses/commissions eligibility

Flexible paid time off (PTO) and sick

Job summary

Syneos Health, Inc. is seeking a Sr. Site Contract Lead in the United States to lead CRO site contract escalations and drive first-pass negotiations. You will align templates, provide clear decision paths, and coordinate with study teams, Legal, and Procurement to ensure timely, compliant agreements.

Your role involves analyzing risks, guiding negotiations with CRO partners, and implementing improvements to reduce escalations while maintaining sponsor protections and operational excellence.

Responsibilities

• Serve as primary point of contact for CRO site contract escalations and manage intake, triage, and resolution.
• Align on templates and approved fallback language with CRO partners to enable efficient first-pass negotiations.
• Enable CRO-led negotiation while owning sponsor-required exceptions with clear decision pathways.
• Resolve complex legal and operational contracting issues, assess deviations, and advise CROs; escalate to Legal when needed.
• Build partnerships across CROs, internal teams, and Legal to align expectations and keep negotiations progressing.
• Identify trends, drive improvements, and propose updates to templates, decision rights, and CRO training.
• Maintain escalation governance and knowledge management with auditable negotiation approaches.
• Provide leadership through practical negotiation guidance and best practices to CROs and internal teams.
• Apply a risk-based approach to protect sponsor requirements and involve Legal when thresholds are exceeded.

Job description

Sr. Site Contract Lead

Syneos Health® is a leading fully-integrated life sciences services organization built to accelerate customer success. We partner with innovators at every point across the drug development and commercialization continuum, helping them navigate complexity, anticipate change and accelerate progress.

Our Clinical Solutions team members act with a drug development mindset, applying their years of experience and deep expertise to truly understand customer needs and represent those in the solutions we shape.

Whether you join us in a Functional Service Provider partnership or a Full-Service environment, you’ll collaborate with passionate problem solvers, innovating as a team to help our customers achieve their goals. We are agile and driven to deliver – for one another, our customers, and, most importantly, for those in need.

Discover what your 25,000 future colleagues already know:

Why Syneos Health

• We are passionate about developing our people, through career development and progression; supportive and engaged line management; technical and therapeutic area training; peer recognition and total rewards program.
• We are committed to building an inclusive culture – where you can authentically be yourself. Central to this is our purpose – Driven to Deliver – which captures the passion of our colleagues to show up each day and shape solutions that have the ability to dramatically impact someone’s life.
• We are continuously building the company we all want to work for and our customers want to work with. Why? Because we know that when we bring together smart colleagues from across the world, we can shape the future of healthcare, driving impact for customers and defining the pace of patient progress.

Job Responsibilities

Key Responsibilities

• Serve as primary point of contact for CRO site contract escalationsOwn the intake, triage, and resolution of escalations from CRO partners, ensuring timely decisions and clear guidance.
• Align on templates and approved fallback language with CRO partnersPartner with CROs and stakeholders to maintain fit-for-purpose templates, playbooks, and fallback positions that enable efficient first-pass negotiations.
• Enable CRO-led negotiation while owning sponsor-required exceptions Set clear decision pathways so CROs negotiate the majority of agreements using their expertise and approved positions, while escalated cases receive consistent review and direction.
• Resolve complex legal and operational contracting issues Assess proposed contract deviations, recommend acceptable alternatives, and provide clear feedback to CROs; escalated to Legal for guidance when required due to novel risk, policy questions, or non-standard positions.
• Build strong partnerships across CROs, internal teams, and Legal stakeholders Collaborate with study teams, Legal, Procurement, and other stakeholders to align expectations, ensure consistent decisions, and keep negotiations progressing.
• Identify trends and drive continuous improvement Analyze escalation drivers and cycle-time impacts; recommend solutions such as expanding fallback language, clarifying decision rights, updating templates, and targeting CRO training to reduce unnecessary escalations.
• Maintain escalation governance and knowledge management Document decisions, rationale, and outcomes to build a usable knowledge base for CRO partners and internal stakeholders, supporting consistent, auditable negotiation approaches.
• Provide leadership through influence and guidance Act as a trusted expert for CROs and internal teams by offering practical negotiation guidance, sharing best practices, and reinforcing the agreed escalation pathways.
• Apply a risk-based approach to protect sponsor requirements Evaluate escalated terms for legal, financial, and operational risk; ensure alignment with applicable standards and requirements and appropriately involve Legal when risk or policy thresholds are exceeded.

At Syneos Health, we believe in providing an environment and culture in which Our People can thrive, develop and advance. We reward and recognize our people by providing valuable benefits and a quality-of-life balance. The benefits for this position may include a company car or car allowance, Health benefits to include Medical, Dental and Vision, Company match 401k, eligibility to participate in Employee Stock Purchase Plan, Eligibility to earn commissions/bonus based on company and individual performance, and flexible paid time off (PTO) and sick time. Because certain states and municipalities have regulated paid sick time requirements, eligibility for paid sick time may vary depending on where you work. Syneos complies with all applicable federal, state, and municipal paid sick time requirements.

• company car or car allowance
• Health benefits to include Medical, Dental and Vision
• Company match 401k
• eligibility to participate in Employee Stock Purchase Plan
• Eligibility to earn commissions/bonus based on company and individual performance
• flexible paid time off (PTO) and sick time

Salary Range:

$67,700.00 - $115,100.00

The base salary range represents the anticipated low and high of the Syneos Health range for this position. Actual salary will vary based on various factors such as the candidate’s qualifications, skills, competencies, and proficiency for the role.

Get to know Syneos Health

Over the past 5 years, we have worked with 94% of all Novel FDA Approved Drugs, 95% of EMA Authorized Products and over 200 Studies across 73,000 Sites and 675,000+ Trial patients.

No matter what your role is, you’ll take the initiative and challenge the status quo with us in a highly competitive and ever-changing environment. Learn more about Syneos Health.

http://www.syneoshealth.com

Additional Information

Tasks, duties, and responsibilities as listed in this job description are not exhaustive. The Company, at its sole discretion and with no prior notice, may assign other tasks, duties, and job responsibilities. Equivalent experience, skills, and/or education will also be considered so qualifications of incumbents may differ from those listed in the Job Description. The Company, at its sole discretion, will determine what constitutes as equivalent to the qualifications described above. Further, nothing contained herein should be construed to create an employment contract. Occasionally, required skills/experiences for jobs are expressed in brief terms. Any language contained herein is intended to fully comply with all obligations imposed by the legislation of each country in which it operates, including the implementation of the EU Equality Directive, in relation to the recruitment and employment of its employees. The Company is committed to compliance with the Americans with Disabilities Act, including the provision of reasonable accommodations, when appropriate, to assist employees or applicants to perform the essential functions of the job.