Sr. Scientist I, Analytical Development & Solutions

Merck & Co.; Irvine (CA); On-site; USD 106,000 - 113,000; Full time

Benefits offered by this job

Medical, Dental, Vision

Life Insurance

401k

Paid Time Off

Job summary

FUJIFILM Biosciences in Irvine, CA is seeking a Senior Scientist I to independently develop advanced analytical methods and lead MS-based proteomics, biologics characterization, and bioprocessing projects. The role includes supervising researchers, data analysis, and cross-functional support for product development.

The candidate will guide experimental design, implement workflow improvements, and mentor team members while collaborating with internal partners to advance life-science solutions.

Qualifications

• B.S./M.S./Ph.D. with extensive relevant experience in life sciences or engineering.
• 10+ years in relevant field; Bioprocessing/Chemistry/Biochemistry emphasis.
• Mass Spectrometry & Proteomics: high-resolution MS proficiency for peptide mapping, proteomics, PTMs, small molecule characterization.
• Biologics: monoclonal antibody analysis and spent media evaluation.
• Analytical instrumentation: MS, HPLC/UPLC, ICP-MS, UV-Vis; solid-state methods.
• Data software & automation: Protein Metrics, Python, R; automation in bioprocessing.

Responsibilities

• Lead complex R&D projects from concept to completion.
• Oversee experimental design, data analysis, and presentations.
• Mentor and supervise team members; manage budgets and timelines.
• Independently perform advanced data analysis on complex datasets.
• Develop new testing methods and workflows for product development.
• Troubleshoot equipment and processes; drive process improvements.
• Interpret literature to inform experimental design and decisions.

Skills

Mass Spectrometry

Proteomics

Biologics characterization

Analytical instrumentation

Data software

Automation

Project leadership

Data analysis

Literature interpretation

Troubleshooting

Education

B.S. or higher in science/engineering

M.S. in related field

Ph.D. in related field

Tools

Protein Metrics

Python

R

HPLC/UPLC

ICP-MS

UV-Vis

FT-IR/Raman

XRF

SEM

Job description

Position Overview

We are hiring a Senior Scientist I, Analytical Development & Solutions. The Senior Scientist I, Analytical Development & Solutions independently develops advanced analytical methods and leads complex R&D projects involving mass spectrometry, proteomics, biologics characterization, bioprocessing, and laboratory automation. This role manages projects from concept through completion, performs complex data analysis and troubleshooting, drives process improvements, provides cross-functional technical support, and may supervise up to two research scientists. The position requires strong scientific judgment, communication skills, and substantial relevant experience supported by a degree in science, engineering, or a related field.

Company Overview

At FUJIFILM Biosciences, we turn curiosity into breakthroughs that advance the field of life sciences. By offering a comprehensive portfolio of products and services in cell culture media, discovery research reagents, recombinant growth factors and proteins, fine chemicals, and critical assay materials, we partner with the brightest minds in biotech and pharma to tackle the world's biggest health challenges.

Imagine being part of a team that enables life-changing discoveries like new vaccines, therapies, and advancements in regenerative medicine. Our culture fosters curiosity, collaboration, and innovation, and we pride ourselves on delivering unparalleled quality and service to our partners. If you're ready to make an impact, your future belongs with us at FUJIFILM Biosciences.

Our headquarters in Santa Ana, California, is surrounded by world-class schools, lush parks, and scenic beaches like Laguna and Huntington, making it an ideal place to live, work, and explore. With additional campuses across the US, Europe, China, and Japan, we offer opportunities to make a difference worldwide.

Fujifilm is globally headquartered in Tokyo with over 70,000 employees across four key business segments of healthcare, electronics, business innovation, and imaging. We are guided and united by our Group Purpose of "giving our world more smiles." Visit: https://www.fujifilm.com/us/en/about/region/careers

Job Description

Responsibilities:

• Mass Spectrometry & Proteomics Expertise: Required proficiency in high-resolution mass spectrometry (Orbitrap, QTOF, LC-MS/MS) for peptide mapping, proteomics, post-translational modifications (PTMs), and small molecule structural characterization.
• Biologics Characterization: Highly preferred experience with monoclonal antibody analysis (intact, subunits, glycan profiling) and the evaluation of spent media.
• Analytical & Solid-State Instrumentation: Extensive experience operating standard analytical instruments (HPLC/UPLC, ICP-MS, UV-Vis) alongside solid-state techniques (FT-IR/Raman, XRF, SEM).
• Data Software & Automation: Preferred knowledge of MS data software (Protein Metrics), bioinformatics/statistical programming (Python, R), automation platforms, and upstream/downstream bioprocessing.
• Expert in commonly used experimental/research concepts, practices, and procedures with advanced working knowledge of basic laboratory equipment (scales, pH meters, etc.)
• Independently lead projects from conception to conclusion managing budgets, timelines, cross-functional communication - while providing high-level mentorship to team members. Responsible for supervising lead project staff by overseeing experimental design, data analysis, and oral presentations.
• Perform advanced data analysis from complex data sets, use of statistical software and generate summary data reports & presentations independently.
• Able to interpret scientific literature, apply knowledge to projects (e.g. experimental design information, concentration ranges, etc.), use information to develop new and novel ideas/concepts/product development
• Expert critical thinking skills. Has an intuitive grasp of complex data and moves straight to the solution.
• Able to troubleshoot equipment and experimental problems independently and implement process/workflow improvements, product development and introduction of new testing methods/assays.

Required Skills/Education:

• B.S. in a science, bioscience, engineering or bioengineering field with >10 years of relevant work experience or M.S. with >8 years or Ph.D. with >2 years of relevant working experience
• Minimum five years of relevant experience, with emphasis in Bioprocessing, Chemistry, and Biochemistry
• Mass Spectrometry & Proteomics Expertise: Required proficiency in high-resolution mass spectrometry (Orbitrap, QTOF, LC-MS/MS) for peptide mapping, proteomics, post-translational modifications (PTMs), and small molecule structural characterization.
• Biologics Characterization: Highly preferred experience with monoclonal antibody analysis (intact, subunits, glycan profiling) and the evaluation of spent media.
• Analytical & Solid-State Instrumentation: Extensive experience operating standard analytical instruments (HPLC/UPLC, ICP-MS, UV-Vis) alongside solid-state techniques (FT-IR/Raman, XRF, SEM).
• Data Software & Automation: Preferred knowledge of MS data software (Protein Metrics), bioinformatics/statistical programming (Python, R), automation platforms, and upstream/downstream bioprocessing, preferred.
• Working knowledge of Bioprocessing, Chemistry and Biochemistry
• Cell Culture experience preferred
• Ability to speak, read and write English proficiently.
• Good oral and written communication skills

Salary and Benefits:

• For California, the base salary range for this position is $106,185.25 - $113,000. Compensation for the successful candidate will depend on various factors (e.g., qualifications, education, prior experience, location, etc.).
• Medical, Dental, Vision
• Life Insurance
• 401k
• Paid Time Off

*#LI-onsite

EEO Information

Fujifilm is committed to providing equal opportunities in hiring, promotion and advancement, compensation, benefits, and training regardless of nationality, age, gender, sexual orientation or gender identity, race, ethnicity, religion, political creed, ideology, national, or social origin, disability, veteran status, etc.

ADA Information

If you require reasonable accommodation in completing this application, interviewing, completing any pre-employment testing, or otherwise participating in the employee selection process, please direct your inquiries to our HR Department ([e-mail]).