Sr Scientist, Data Scientist-Process Sciences (Contract)

Allogene Therapeutics; South San Francisco (CA); Hybrid; USD 62,000 - 96,000; Part time

Job summary

Allogene Therapeutics in South San Francisco, CA is seeking a Senior Scientist/Scientist, Computational Biology to strengthen the Cell Starting Material - Process Sciences team. The role focuses on developing analytical capabilities, applying computational methods, and advancing bioinformatics within a fast-paced, biotech environment.

The position offers hybrid work (onsite 3 days/week) or remote with travel to our South San Francisco headquarters, and requires expertise in QbD, statistical

Qualifications

• BS/MS/PhD in computational biology, bioinformatics, biostatistics, genomics, or related fields
• Experience with statistical modeling in biologics or cell therapy space is highly preferred
• Experience with multivariate data analysis and common statistical software (JMP, R-Studio, Python)

Responsibilities

• Develop and implement Cell Starting Material characterization studies using QbD principles to support process understanding, optimization, and characterization activities
• Apply advanced statistical, computational biology and bioinformatics tools to large and complex data sets to advance raw materials and product understanding
• Support clinical‑scale non‑GMP manufacturing operations for execution of BLA‑enabling process characterization activities
• Contribute to process characterization efforts and continuous improvement initiatives to enhance CAR‑T manufacturing processes and capabilities
• Integrate data across platforms and timepoints to support translational and clinical decision-making
• Collaborate with Project Technical Teams and communicate effectively with all stakeholder groups
• Train wet-lab scientists — translating computational outputs into actionable insights
• Present data/strategy to scientists and management in internal venues
• Remain current with cell therapy, immunology, and bioprocessing literature
• Other duties as assigned

Skills

Computational biology

Bioinformatics

Biostatistics

Data analysis

Statistical modeling

Multivariate data analysis

Education

PhD in computational biology

MS in computational biology

BS in computational biology or related field

Tools

JMP

R-Studio

Python

Data dashboards

Job description

About Allogene:

Allogene Therapeutics, with headquarters in South San Francisco, is a clinical-stage biotechnology company pioneering the development of allogeneic chimeric antigen receptor T cell (AlloCAR T) products for cancer and autoimmune disease. Led by a management team with significant experience in cell therapy, Allogene is developing a pipeline of “off-the-shelf” CAR T cell product candidates with the goal of delivering readily available cell therapy on-demand, more reliably, and at greater scale to more patients.

About the role:

Allogene is seeking a highly motivated Senior Scientist/Scientist, Computational Biology to support the Cell Starting Material - Process Sciences group within the Process and Product development organization. Candidates interested in developing new analytical capabilities, advancing computational approaches, and helping strengthen our bioinformatics function are strongly encouraged to apply.

This role can be based out of our headquarters in South San Francisco, CA hybrid onsite 3 days a week or remote with travel to Allogene’s South San Francisco headquarters.

Responsibilities include, but are not limited to:

• Actively contributes to the development and implementation of Cell Starting Material characterization studies using QbD principles to support process understanding, optimization, and characterization activities.


• Applied advanced statistical, computational biology and bioinformatics tools to large and complex data sets to advance raw materials and product understanding.


• Support clinical‑scale non‑GMP manufacturing operations for execution of BLA‑enabling process characterization activities.


• Support and contribute to process characterization efforts and continuous improvement initiatives aimed at enhancing CAR‑T manufacturing processes and capabilities (e.g., evaluation of process parameters, materials, closed or disposable systems, and operational workflows).


• Integrate data across platforms and timepoints to support translational and clinical decision-making


• Contribute to Project Technical Teams and communicate and collaborate effectively to ensure effective interactions with all stakeholder groups.


• Collaborate with and train wet-lab scientists — translating computational outputs into actionable insights and building shared understanding across experimental and computational disciplines


• Present data/strategy to scientists (and management) in internal venues (technical meetings, Project Team meetings) as appropriate.


• Remain current with relevant cell therapy, immunology, and bioprocessing literature.


• Other duties as assigned

Position Requirements & Experience:

• BS/MS/PhD in computational biology, bioinformatics, biostatistics, genomics, or a closely related quantitative fields.


• MS plus at least 2 years of experience or BS with at least 5 years of experience


• A demonstrated foundational understanding of mammalian or primary cell culture, biochemistry, molecular & cell biology and immunology (required for enhanced product & process understanding).


• Experience in Quality by Design methodologies and statistical modeling in biologics or cell therapy space is highly preferred.


• Experienced with multivariate data analysis, preferred experience with statistical software (JMP, R-Studio, Python).


• Designed and deployed dashboards for real-time process monitoring, improving data accessibility and decision-making capabilities.


• Experience with prior Gene & Cell Therapy manufacturing preferred but not required.


• Experience in genetic modification of cells using gene editing and gene delivery technologies preferred but not required.


• Ability to work in a fast-paced, startup environment.


• Strong attention to detail with the ability to multi-task and handle multiple responsibilities simultaneously.


• Excellent organizational skills and an ability to prioritize effectively to deliver results within reasonably established timelines.


• Ability to work independently and as part of a team.


• Strong interpersonal skills including verbal and written communication are essential in this collaborative work environment.


• Candidates must be authorized to work in the U.S.


• This is a 1-year contract opportunity with the possibility of extension or contract-to-hire.

We offer a chance to work with talented people in a collaborative environment. The expected salary range for this role is $45.00 to $70.00 per hour. Actual pay will be determined based on experience, qualifications, geographic location, business needs, and other job-related factors permitted by law.

As an equal opportunity employer, Allogene is committed to a diverse workforce. Employment decisions regarding recruitment and selection will be made without discrimination based on race, color, religion, national origin, gender, age, sexual orientation, physical or mental disability, genetic information or characteristic, gender identity and expression, veteran status, or other non-job-related characteristics or other prohibited grounds specified in applicable federal, state and local laws. We also embrace differences in experience and background, and welcome diversity of opinions and thought with active recruitment and internships designed to create a stronger and better Allogene that is focused on developing life-changing products for patients.