Sr Scientist

BioSpace; Village of Tarrytown (NY); On-site; USD 110,000 - 179,000; Full time

Job summary

Regeneron is seeking a Scientist in Allergy to join the Immunology & Inflammation team in Tarrytown, NY. You will validate targets, assess therapeutic candidate efficacy in disease models, and explore mechanisms of pathology while collaborating closely with your manager and colleagues.

You will perform in vivo and in vitro experiments, including mouse work, flow cytometry, ELISA, and MSD assays. Strong immunology background and team mindset are essential.

Qualifications

• BS/MS with 5-8 years of relevant research experience in immunology.
• Proven experience in tissue culture, cell-based assays, flow cytometry, ELISA, and MSD.
• Strong organizational and communication skills; able to work independently or in a team.

Responsibilities

• Execute experiments and develop new methods to advance project goals.
• Troubleshoot issues, interpret data, and communicate results to the team.
• Work with mice including handling, surgical techniques, and tissue collection.
• Conduct cell culture and in vitro assays (ELISA, cell-based assays).
• Design complex studies to assess therapeutic efficacy in models.
• Perform flow cytometry, panel design, data analysis and interpretation.
• Develop and optimize mouse disease models with multiple readouts.
• Maintain lab, order supplies, and keep accurate records in a fast-paced setting.

Skills

Immunology

Mice handling

Tissue culture

Flow cytometry

ELISA

MSD

Cell-based assays

Data analysis

Communication

Team collaboration

Education

BS/MS in Immunology or related field

PhD (preferred)

Tools

GraphPad Prism

FlowJo

OMIQ

SoftMax Pro

MSD Workbench

Job description

Build Our Future Together At Regeneron, we use science and innovation to develop life-changing medicines for people with serious diseases. We are seeking a Scientist working in the field of Allergy to join our highly collaborative Immunology & Inflammation team. In this role, you will support a broad pipeline in allergic and inflammatory diseases by validating targets, assessing therapeutic candidate efficacy in disease models, and interrogating mechanisms of pathology, while communicating openly and frequently with your manager and team members.

When & Where

Location: Tarrytown, NY

Work model/flexibility: Onsite

Discover Your Role

• Execute experiments based on provided projects/protocols and develop new methods or technologies to advance project goals
• Troubleshoot methodological and technical issues, interpreting data and literature and communicating results to your supervisor, department, or project team
• Work with mice, demonstrating proper handling and care, general surgical techniques, and collection of blood and tissue samples
• Conduct cell culture and various in vitro experiments, including cell-based assays and ELISA
• Design complex studies to interrogate novel therapeutic efficacy using in vitro and in vivo model systems
• Conduct studies using flow cytometry, including panel design, data analysis, and interpretation of findings
• Develop and optimize mouse models of disease, analyzing associated pathologies by flow cytometry, cell-based assays, histology, and ELISA
• Maintain lab and equipment, order supplies/reagents, and keep accurate, complete records in a fast-paced, results-oriented environment

This Role Requires

• BS/MS with 5-8 years of relevant research experience in immunology
• Proven experience in tissue culture (maintenance of transformed and primary cells), cell-based assays, flow cytometry, ELISA, and MSD
• Basic computer skills and experience collecting and analyzing biological data
• Strong organizational and communication skills, with the ability to work independently and as part of a team
• Preferred: Ph.D. in Biology, Immunology, or Cellular and Molecular Biology, with knowledge of allergic diseases and B-cell/plasma cell biology
• Preferred: training in proper handling and care of mice, general surgical techniques, and collection of blood and tissue samples
• Preferred: experience with GraphPad Prism, FlowJo and/or OMIQ, SoftMax Pro, and Meso Scale Discovery (MSD) Workbench software

We are committed to building a workplace with an inclusive culture. Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion or belief (or lack thereof), sex, sexual orientation, gender identity or expression, gender reassignment, marital or civil partnership status, civil status, pregnancy or parental status, age, disability, nationality, citizenship status, ethnic or national origin, membership of the Traveler community, familial status, genetic information, military or veteran status, or any other characteristic protected under applicable law. Where required, we will provide reasonable accommodation to applicants with known disabilities or chronic illnesses during the recruitment process, unless such accommodation would impose undue hardship.

Regeneron offers a competitive and comprehensive total rewards package which may include, depending on country and role: annual bonuses or other incentive plans, equity awards, pension or retirement benefits, 401(k) company match, health and wellness programs, fitness centers, insurance benefits (e.g. medical, dental, vision, life and disability), paid time off, and family support benefits. For additional information about Regeneron benefits in the U.S., please visit https://careers.regeneron.com/en/working-at-regeneron/total-rewards/. For other locations, additional information will be provided during the recruitment process.

As part of the recruitment process, certain background checks may be conducted in accordance with the laws of the country where the position is based. The purpose of such checks is to verify certain information prior to the commencement of employment such as identity, right to work and educational qualifications.

For jobs in Canada: this posting is for an existing position.

Salary Range (annually): $109,900.00 - $179,300.00