Sr Project Manager - Full Service

Syneos Health/ inVentiv Health Commercial LLC; United States; On-site; USD 110,000 - 140,000; Full time

Job summary

Syneos Health is seeking a Senior Project Manager for Clinical Operations - Full Service. You will lead cross-functional teams, manage budgets, and ensure delivery of complex global trials from startup to closeout. The role requires hands-on study execution, adherence to GCP/ICH guidelines, and strong client communication.

.Reporting to leadership, you will oversee timelines, risks, and performance while mentoring junior staff and coordinating with sponsors to drive successful outcomes.

Qualifications

• CRO experience required and demonstrated ability to manage trials from initiation to closeout.
• Strong communication, presentation and leadership skills.
• Willingness to travel up to 25%.

Responsibilities

• Independently manage clinical studies from startup through closeout.
• Lead Phase II/III trials, including global and multi-protocol studies.
• Act as primary liaison between sponsors and internal teams.
• Ensure studies comply with GCP, ICH, and regulatory requirements.
• Oversee timelines, budgets, resources, risks and deliverables.
• Mentor junior project staff and promote cross-functional collaboration.

Skills

GCP knowledge

ICH Guidelines

Cross-functional leadership

Budget management

Education

Bachelor's degree in Life Sciences or related field

Job description

Sr Project Manager - Full Service

Syneos Health is a leading fully integrated biopharmaceutical solutions organization built to accelerate customer success. We translate unique clinical, medical affairs and commercial insights into outcomes to address modern market realities.

Our Clinical Development model brings the customer and the patient to the center of everything that we do. We are continuously looking for ways to simplify and streamline our work to not only make Syneos Health easier to work with, but to make us easier to work for.

Whether you join us in a Functional Service Provider partnership or a Full-Service environment, you'll collaborate with passionate problem solvers, innovating as a team to help our customers achieve their goals. We are agile and driven to accelerate the delivery of therapies, because we are passionate to change lives.

Discover what our 29,000 employees, across 110 countries already know:

WORK HERE MATTERS EVERYWHERE

Why Syneos Health

• We are passionate about developing our people, through career development and progression; supportive and engaged line management; technical and therapeutic area training; peer recognition and total rewards program.
• We are committed to our Total Self culture - where you can authentically be yourself. Our Total Self culture is what unites us globally, and we are dedicated to taking care of our people.
• We are continuously building the company we all want to work for and our customers want to work with. Why? Because when we bring together diversity of thoughts, backgrounds, cultures, and perspectives - we're able to create a place where everyone feels like they belong.

Job Responsibilities

The Senior Project Manager, Clinical Operations - Full Service is responsible for providing customer-focused leadership in the management and delivery of the operational, financial, and strategic aspects of clinical research projects from proposal development through final deliverables. This role oversees studies ranging from single-service programs to large-scale, full-service global clinical trials across multiple phases and therapeutic areas. The Senior Project Manager serves as the primary client contact, leads cross-functional teams, and ensures projects are delivered on time, within budget, and in compliance with quality and regulatory standards.

This position requires a hands-on project manager who is actively involved in study execution and capable of independently leading complex clinical trials with minimal supervision.

Key Responsibilities

Project Leadership & Delivery

• Independently manage clinical studies from startup through closeout.
• Lead the operational and financial execution of Phase II and III clinical trials, including global and multi-protocol studies.
• Act as the primary liaison between sponsors and internal project teams.
• Ensure studies are conducted in accordance with GCP, ICH guidelines, regulatory requirements, and company SOPs.
• Oversee project timelines, budgets, resources, risks, and deliverables.
• Drive day-to-day study execution and proactively identify and resolve project issues.
• Coordinate activities across functional teams and external partners to ensure successful project delivery.
• Maintain accountability for project quality, financial performance, and customer satisfaction.

Client & Stakeholder Management

• Build and maintain strong relationships with sponsors and key stakeholders.
• Lead client meetings and provide regular project updates.
• Independently prepare and present project materials for internal and external meetings.
• Participate in bid defense meetings and business development activities as the designated Project Manager.
• Support client growth opportunities through exceptional project delivery and relationship management.

Financial & Operational Oversight

• Manage project budgets, forecasting, and financial performance.
• Monitor project progress through timelines, metrics, tracking tools, and reporting systems.
• Develop risk mitigation and contingency plans to ensure successful project outcomes.
• Ensure inspection readiness, including oversight of Trial Master Files and project documentation.
• Prepare project reports for sponsors and senior leadership.

Team Leadership & Mentoring

• Lead and motivate cross-functional project teams.
• Mentor and support junior Project Managers and Project Support staff.
• Facilitate project-specific and therapeutic area training as needed.
• Promote collaboration, communication, and accountability across teams.

Required Qualifications

• Minimum Bachelor's degree in Life Sciences, Medicine, Nursing, Pharmacy, or a related discipline, or equivalent combination of Bachelor's degree and experience.
• Clinical Research Organization (CRO) experience required.
• Proven experience independently managing clinical trials from initiation through closeout.
• Strong hands-on cross-functional project management experience with direct involvement in study execution.
• Experience independently managing project budgets, timelines, resources, and client relationships.
• Strong knowledge of GCP, ICH Guidelines, regulatory requirements, and the clinical development process.
• Excellent communication, presentation, interpersonal, and leadership skills.
• Ability to work independently while managing multiple priorities in a fast-paced environment.
• Willingness to travel up to approximately 25%.

We are always excited to connect with great talent. This posting is intended for a [possible] upcoming opportunity rather than a live role. By expressing your interest, you'll be added to our talent pipeline and considered should this role become available.

At Syneos Health, we believe in providing an environment and culture in which Our People can thrive, develop and advance. We reward and recognize our people by providing valuable benefits and a quality-of-life balance. The benefits for this position may include a company car or car allowance, Health benefits to include Medical, Dental and Vision, Company match 401k, eligibility to participate in Employee Stock Purchase Plan, Eligibility to earn commissions/bonus based on company and individual performance, and flexible paid time off (PTO) and sick time. Because certain states and municipalities have regulated paid sick time requirements, eligibility for paid sick time may vary depending on where you work. Syneos complies with all applicable federal, state, and municipal paid sick time requirements.

Salary Range

The base salary range represents the anticipated low and high of the Syneos Health range for this position. Actual salary will vary based on various factors such as the candidate's qualifications, skills, competencies, and proficiency for the role.

Get to know Syneos Health

Over the past 5 years, we have worked with 94% of all Novel FDA Approved Drugs, 95% of EMA Authorized Products and over 200 Studies across 73,000 Sites and 675,000+ Trial patients.

No matter what your role is, you'll take the initiative and challenge the status quo with us in a highly competitive and ever-changing environment. Learn more about Syneos Health.

http://www.syneoshealth.com

Additional Information

Tasks, duties, and responsibilities as listed in this job description are not exhaustive. The Company, at its sole discretion and with no prior notice, may assign other tasks, duties, and job responsibilities. Equivalent experience, skills, and/or education will also be considered so qualifications of incumbents may differ from those listed in the Job Description. The Company, at its sole discretion, will determine what constitutes as equivalent to the qualifications described above. Further, nothing contained herein should be construed to create an employment contract. Occasionally, required skills/experiences for jobs are expressed in brief terms. Any language contained herein is intended to fully comply with all obligations imposed by the legislation of each country in which it operates, including the implementation of the EU Equality Directive, in relation to the recruitment and employment of its employees. The Company is committed to compliance with the Americans with Disabilities Act, including the provision of reasonable accommodations, when appropriate, to assist employees or applicants to perform the essential functions of the job.