Sr. Program Manager, Plasmid DNA / Cell and Gene Therapies (Client-Facing)

Radiometer; United States; Remote; USD 150,000 - 165,000; Full time

Benefits offered by this job

paid time off

medical/dental/vision insurance

401(k)

Job summary

Aldevron, a Danaher operating company, seeks a Senior Program Manager for plasmid DNA programs focused on marketed products, commercial supply, and late-phase clinical programs from validation through launch. You will serve as the senior client-facing leader coordinating scope, schedule, quality, and financial performance with cross-functional teams.

The role reports to the Vice President, North America Sales, is located in Fargo, ND, and will be fully remote.

Qualifications

• Requires a B.S./B.A. and an advanced scientific degree.
• 7+ years in a client-facing project/program/account management role in life sciences, GMP-regulated CDMO preferred.
• Experience managing programs and contracts in regulated biotech/pharma/medical device fields.

Responsibilities

• Lead highly complex, multi-program plasmid DNA portfolios with senior client stakeholders.
• Align scope, schedule, quality, supply continuity, and financial performance across programs.
• Translate agreements into executable operating requirements and drive negotiations with Legal, Contracts, and Finance.
• Monitor program health, capacity, forecasting, risks, and opportunities; report to senior leadership.

Skills

Client-facing leadership

Program management

Strategic account management

Cross-functional collaboration

GMP/CDMO experience

Education

Bachelor's degree

Advanced degree in science

Job description

Bring more to life. Are you ready to accelerate your potential and make a real difference within life sciences, diagnostics and biotechnology? At Aldevron, one of Danaher's 15+ operating companies, our work saves lives, and we're all united by a shared commitment to innovate for tangible impact. You'll thrive in a culture of belonging where you and your unique viewpoint matter. And by harnessing Danaher's system of continuous improvement, you help turn ideas into impact - innovating at the speed of life. At Aldevron, we deliver world‑class CDMO services that accelerate the development of groundbreaking therapies. Our mission is to be the engine of innovation for genomic medicine pioneers. As a member of our team, you'll help bring life‑changing innovations to life - impacting millions around the world. We bring together deep scientific expertise, an unwavering commitment to quality, and a collaborative spirit to drive progress. Whether you're launching your career or bringing years of experience, we value the unique perspective you bring.

Position Overview

Senior Program Manager, Plasmid DNA is responsible for leading Aldevron's most strategic and complex plasmid DNA programs, with a primary focus on marketed products, commercial supply, and late‑phase clinical programs progressing through process validation, Process Performance Qualification (PPQ), regulatory readiness, and commercial launch. This role serves as the senior client‑facing program leader for assigned programs and integrates commercial agreements with technical and operational execution.

The Program Manager ensures alignment across scope, schedule, quality, supply continuity, financial performance, regulatory expectations, and customer commitments throughout validation, PPQ, launch preparation, recurring commercial supply, and lifecycle management.

The Program Manager partners closely with Business Development, Legal, Contracts, Project Management, Manufacturing, Quality, Regulatory Affairs, Supply Chain, Technical Operations, Finance, and Executive Leadership to convert contractual commitments into executable plans, resolve complex issues, protect Aldevron's business interests, and build durable strategic client partnerships.

This position reports to the Vice President, North America Sales and is part of the Program Management Organization located in Fargo, ND and will be fully remote.

Key Responsibilities

• Lead highly complex, multi-program portfolios across strategic accounts, owning end-to-end delivery across multiple concurrent projects with significant revenue, risk, and cross‑functional dependencies, ensuring alignment with timelines, budgets, and KPIs.
• Own and influence senior‑level client relationships and account strategy, acting as a trusted advisor to client stakeholders, navigating escalations, and shaping program direction and long‑term partnership outcomes.
• Drive enterprise-wide alignment and decision‑making, leading cross-functional teams through ambiguity, resolving competing priorities, and influencing outcomes across functions and leadership levels.
• Establish and maintain program governance structures, track project metrics, forecast capacity, and provide regular updates to senior leadership on project status, risks, and opportunities.
• Translate master service agreements, statements of work, supply and quality agreements, amendments, and change orders into executable operating requirements, and partner with Business Development, Legal, Contracts, and Finance to assess feasibility, manage scope change, support negotiations, and protect Aldevron's commercial and contractual position.
• Responsible for overall program health, capacity strategy, business growth, including forecasting demand, identifying risks, leading proposals and renewals, and influencing account expansion and continuous improvement initiatives.

Essential Requirements

• B.S. or B.A. required.
• Advanced degree in scientific field strongly preferred (e.g. molecular biology, biology, biotechnology, biochemistry).
• Prefer 7+ years of experience in a client‑facing role as a project, program, or account manager within the life sciences, with preference for 5+ years in a GMP‑regulated CDMO environment.
• Experience managing programs and contracts in a regulated biotechnology, pharmaceutical, or medical device related field required.
• Working knowledge of plasmid DNA manufacturing and its use in cell and gene therapy, gene editing, mRNA, vaccines, or other genomic medicine applications; strong preference for late phase/commercial drug product experience.
• Strong analytical and problem‑solving skills, with the ability to forecast risks and implement sustainable solutions.
• It would be a plus if you also possess previous experience in: An advanced degree in a scientific, engineering, legal, project management, or business discipline, or a program or project management certification such as PMP.
• Direct program leadership for commercial or late‑phase plasmid DNA programs through process characterization, technology transfer, process validation, PPQ campaigns, regulatory inspections, commercial launch, recurring supply, or post‑approval lifecycle management.
• Experience managing strategic accounts, cross‑site programs, long‑term supply agreements, capacity reservation models, demand planning, forecast commitments, pricing protections, change‑order mechanisms, termination provisions, executive governance, or commercial supply continuity.

Travel, Motor Vehicle Record & Physical/Environment Requirements

Ability to travel up to 25% of the time, including travel to the Fargo, ND site and client locations, with overnight travel based on business and customer needs.

Work Arrangement

Aldevron, a Danaher operating company, offers a broad array of comprehensive, competitive benefit programs that add value to our lives. Whether it’s a health care program or paid time off, our programs contribute to life beyond the job. Explore the flexibility and challenge that working for Aldevron can provide. This position is eligible for a remote work arrangement in which you can work remotely from your home. Additional information about this remote work arrangement will be provided by your interview team.

Benefits

• paid time off
• medical/dental/vision insurance
• 401(k) to eligible employees

Salary and Incentives

The annual salary range for this role is $150,000-165,000. This is the range that we in good faith believe is the range of possible compensation for this role at the time of this posting. This range may be modified in the future. This job is also eligible for bonus/incentive pay.

Equal Opportunity Statement

Danaher Corporation and all Danaher Companies are committed to equal opportunity regardless of race, color, national origin, religion, sex, age, marital status, disability, veteran status, sexual orientation, gender identity, or other characteristics protected by law. The U.S. EEO posters are available here.

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We comply with federal and state disability laws and make reasonable accommodations for applicants and employees with disabilities. If reasonable accommodation is needed to participate in the job application or interview process, to perform essential job functions, and/or to receive other benefits and privileges of employment, please contact: 1-202-419-7762 or [e-mail].

Danaher is a leading global life sciences, biotechnology, and diagnostics innovator, helping to solve many of the world’s most important health challenges, ultimately improving quality of life for billions of people today, while setting the foundation for a healthier, more sustainable tomorrow. The Danaher ecosystem is made up of more than 15 businesses united by a shared commitment to innovate for tangible impact. Please read our Applicant Data Privacy Notice carefully here.

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Together, we’ll accelerate the real‑life impact of tomorrow’s science and technology. We partner with customers across the globe to help them solve their most complex challenges, architecting solutions that bring the power of science to life. For more information, visit www.danaher.com.