Sr. Manager Solution Prep

Amgen; West Greenwich (RI); On-site; USD 136,000 - 184,000; Full time

Benefits offered by this job

Retirement plan

Medical, dental, vision

Stock-based incentives

Flexible work model

Job summary

Amgen Inc. is seeking a Sr. Manager Manufacturing to lead the AR5 Solution Preparation organization in a 24/7 biomanufacturing network. You will oversee a team of over 50 staff, ensuring safe, compliant operations and strong performance across four shifts.

The role emphasizes capacity planning, continuous improvement, and mentoring Front‑Line Managers to align with AR5 and AR30 objectives while advancing digital, data-driven decision making.

Qualifications

• Minimum of 2 years direct people management or leadership experience.
• Experience in manufacturing operations and regulatory compliance.
• Strong problem-solving and cross-functional collaboration skills.

Responsibilities

• Lead the Solution Preparation organization to meet 24/7 production goals.
• Oversee Front-Line Managers and ensure compliance with GMP and safety standards.
• Drive continuous improvement and digital tooling adoption across AR5/AR30.
• Plan capacity, coordinate with Quality, Engineering and Supply Chain.
• Develop talent and foster a culture of learning and accountability.
• Support readiness for process improvements and changeovers.

Skills

Leadership

People management

Quality & safety

Education

Bachelor’s degree in a related field

Tools

Copilot

Job description

Career Category Operations Job Description Join Amgen’s Mission of Serving Patients At Amgen, if you feel like you’re part of something bigger, it’s because you are. Our shared mission—to serve patients living with serious illnesses—drives all that we do. Since 1980, we’ve helped pioneer the world of biotech in our fight against the world’s toughest diseases. Amgen is advancing a broad and deep pipeline and portfolio of medicines to treat heart disease, obesity and obesity‑related conditions, rare diseases, inflammatory conditions and cancer. As a member of the Amgen team, you’ll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller, happier lives. Our award‑winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, you’ll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career.At Amgen, if you feel like you’re part of something bigger, it’s because you are. Our shared mission—to serve patients living with serious illnesses—drives all that we do.

Sr. Manager Manufacturing - AR5 Solution Prep

What you will do

Let’s do this. Let’s change the world. In this vital role you will lead the Solution Preparation organization within AR5 — a critical and highly integrated part of Amgen’s large-scale biomanufacturing network. This team plays an essential role in the success of the plant by supplying high-quality media to Cell Culture and buffers to Purification, enabling the reliable and consistent manufacture of Amgen’s biologic medicines. The Senior Manager oversees a team of more than 50 staff working across four shifts, each led by a Front‑Line Manager, ensuring safe, compliant, and efficient 24/7 operations. As a member of the AR5 Manufacturing Leadership Team, this leader shapes operational performance, drives site‑wide alignment, and plays a key role in transforming how we manufacture today to deliver on the processes of tomorrow.

Key Responsibilities

• Safety and Quality Leadership Champion Amgen’s core commitment to safety and product quality by fostering a culture of accountability and continuous improvement. Ensure manufacturing execution consistently meets GMP, EHS, and regulatory expectations, with proactive risk identification and mitigation. Strengthen and build upon an already strong safety and quality culture, reinforcing standards through daily leadership presence on the floor (Gemba).
• Operational Leadership Lead the Solution Preparation organization to achieve production goals across a 24/7 operation. Provide oversight and direction to Front‑Line Managers, ensuring alignment with AR5’s Floor Operating Principles and site objectives. Coordinate cross‑functional support to troubleshoot and resolve operational challenges, including participation in the AR5/AR30 on‑call leadership rotation.
• Strategic and Continuous Improvement Influence site and network‑level manufacturing strategy, driving operational excellence, digital literacy, and adoption of modern manufacturing processes. Lead initiatives to reduce deviations, enhance process reliability, and improve right‑first‑time performance. Champion digital and data‑driven solutions to improve decision‑making, operational transparency, and real‑time performance oversight.
• Innovation and Process Enhancement Drive process transformation efforts that enhance efficiency and eliminate non‑value‑added activities. Lead operational readiness for process improvements, including innovative changeover, scheduling, and resource deployment solutions. Support I‑530 operations, capacity utilization, and scalability across both AR5 and AR30.
• Talent Development Mentor and grow Front‑Line Managers and staff, fostering engagement, belonging, and a mentality of continuous learning. Reinforce Amgen’s Agile Workforce model and OnePlant philosophy by enabling cross‑training and dynamic resource allocation across AR5 and AR30. Build an impactful, adaptable organization prepared to meet the evolving demands of a future‑ready manufacturing network.
• Capacity Planning and Network Collaboration Lead resource planning and capacity modeling to align with Amgen’s long‑range manufacturing plan. Partner closely with Quality, Process Development, Engineering, Safety, Supply Chain, and Technology to ensure integrated, reliable operations. Collaborate across the global Amgen manufacturing network to share best practices, align strategic priorities, and elevate network performance.

What we expect of you

We are all different, yet we all use our unique contributions to serve patients. The dedicated professional we seek is a collaborative partner with these qualifications.

Basic Qualifications

• High School diploma/GED and 12 years of Manufacturing & Operations experience OR Associate's degree and 10 years of Manufacturing & Operations experience OR Bachelor’s degree and 8 years of Manufacturing & Operations experience OR Master’s degree and 6 years of Manufacturing & Operations experience OR Doctorate degree and 2 years of Manufacturing & Operations experience
• In addition to meeting at least one of the above requirements, you must have a minimum of 2 years experience directly managing people and/or leadership experience leading teams, projects, programs, or directing the allocation or resources. Your managerial experience may run concurrently with the required technical experience referenced above.

Preferred Qualifications

• Passion for manufacturing, including people and process
• Demonstrated managerial experience in a regulated manufacturing environment
• Familiarity with GMP regulations as they apply to biotechnology manufacturing
• Skilled in change management, team building, and fostering innovation
• Cross‑functional work experience in a manufacturing‑facing function such as Process Development, Quality, Supply Chain or Engineering
• Excellent communication skills, drive, sense of urgency, and problem‑solving abilities
• Demonstrated experience in applying Operational Excellence and Lean Manufacturing
• Demonstrated ability to forge and maintain strong relationships with other functional areas
• User‑level fluency with digital tools for daily management, data analysis and visualization, and application of Artificial Intelligence (e.g, Copilot, Chat GPT, etc)

What you can expect of us

From our competitive benefits to our collaborative culture, we’ll support your journey every step of the way. The expected annual salary range for this role in the U.S. (excluding Puerto Rico) is posted. Actual salary will vary based on several factors including but not limited to, relevant skills, experience, and qualifications.

• A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts
• A discretionary annual bonus program, or for field sales representatives, a sales‑based incentive plan
• Stock‑based long‑term incentives
• Award‑winning time‑off plans
• Flexible work models where possible.

Salary Range 136,227.80USD -184,308.20 USD

Application deadline

Amgen does not have an application deadline for this position; we will continue accepting applications until we receive a sufficient number or select a candidate for the position.

Sponsorship

Sponsorship for this role is not guaranteed. As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of ethical, committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients. Together, we compete in the fight against serious disease.

Amgen is an Equal Opportunity employer

We make all employment decisions without regard to race, color, religion, sex or any other characteristic protected by applicable law. We provide reasonable accommodations to applicants and employees with disabilities, consistent with legal requirements. Please contact us to request accommodation.