Sr. Manager, Automation – Gtx Lead

Novartis; North Carolina; On-site; USD 114,000 - 212,000; Full time

Benefits offered by this job

Health benefits

401(k) with company match

Equity eligibility

Job summary

Novartis AG in Durham, NC is seeking a Sr. Manager, Automation - GTx Lead to drive automation strategy and lead a high-performing team in a GMP manufacturing environment. You will own critical IT/OT systems, mentor engineers, and collaborate across Quality, Engineering, Manufacturing, and Technical Operations.

The role requires 9+ years of experience, expertise in DCS/PLC/SCADA/MES, and a strong regulatory mindset to support audits and inspections. Onsite role with competitive compensation.

Qualifications

• Strong leadership and mentoring abilities
• Excellent cross-functional collaboration and communication
• Strategic thinking with drive for continuous improvement
• Experience managing 24/7 manufacturing automation operations

Responsibilities

• Lead design, implementation, and support of manufacturing automation systems and process equipment
• Drive continuous improvement to enhance automation performance and reliability
• Oversee site automation strategies aligned with global standards
• Own change controls and CAPAs to drive compliance and improvement
• Lead automation engineers supporting 24/7 operations and audit readiness
• Collaborate with Engineering, Manufacturing, Quality, and Technical Operations

Job description

Summary

Join Novartis and play a pivotal role in advancing next-generation gene therapies through innovative automation leadership. As Sr. Manager, Automation - GTx Lead, you will lead a high-performing team responsible for critical IT/OT and automation systems that enable reliable, compliant, and efficient manufacturing operations. This is an opportunity to shape automation strategy, drive continuous improvement, and influence the future of advanced therapies while collaborating across Engineering, Manufacturing, Quality, and Technical Operations in a fast-paced GMP environment.

About the Role

Location:

• This position will be located in Durham, NC and will be an onsite role.
• Novartis is unable to offer relocation support for this role: please only apply if this location is accessible for you.

Key Responsibilities:

• Lead the design, implementation, maintenance, and support of manufacturing automation systems and process equipment.
• Drive continuous improvement initiatives to enhance automation performance, reliability, and innovation.
• Execute site automation strategies aligned with global Novartis standards and best practices.
• Own and oversee computerized systems supporting critical manufacturing processes.
• Lead, mentor, and develop a team of automation engineers supporting 24/7 operations.
• Establish and improve KPIs to maximize system reliability, availability, and operational excellence.
• Own change controls and CAPAs to drive compliance and continuous improvement.
• Lead automation-related deviation investigations and provide SME expertise for root cause analysis.
• Serve as the automation SME during regulatory inspections and internal or external audits.
• Partner with Engineering, Manufacturing, Quality, and Technical Operations to support new product introductions and site initiatives.

Essential Requirements:

• Bachelor's degree in Engineering or a related field with 9+ years of experience across IT/OT and automation platforms.
• Strong expertise with DCS, PLC, SCADA, MES, Historian systems, and process equipment supporting drug substance and drug product manufacturing.
• Proven experience designing, operating, modifying, maintaining, and retiring computerized systems in a regulated manufacturing environment.
• Demonstrated success leading technical teams and supporting complex 24/7 manufacturing operations.
• Ability to collaborate effectively across Quality Engineering, Quality Assurance, Validation, Engineering, and Manufacturing functions.
• Strong problem-solving, planning, decision-making, and communication skills.
• Knowledge of FDA regulations, cGMP requirements, and health, safety, and environmental standards.
• Proficiency with Microsoft Office, CMMS, Building Management Systems, and related digital tools.

Novartis Compensation and Benefit Summary:

The salary for this position is expected to range between $114,100 and $211,900 annually

The final salary offered is determined based on factors like, but not limited to, relevant skills and experience, and upon joining Novartis will be reviewed periodically. Novartis may change the published salary range based on company and market factors.

Your compensation will include a performance-based cash incentive and, depending on the level of the role, eligibility to be considered for annual equity awards.

US-based eligible employees will receive a comprehensive benefits package that includes health, life and disability benefits, a 401(k) with company contribution and match, and a variety of other benefits. In addition, employees are eligible for a generous time off package including vacation, personal days, holidays and other leaves.

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EEO Statement:

The Novartis Group of Companies are Equal Opportunity Employers. We do not discriminate in recruitment, hiring, training, promotion or other employment practices for reasons of race, color, religion, sex, national origin, age, sexual orientation, gender identity or expression, marital or veteran status, disability, or any other legally protected status.

Accessibility & Reasonable Accommodations

The Novartis Group of Companies are committed to working with and providing reasonable accommodation to individuals with disabilities. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the application process, or to perform the essential functions of a position, please send an e-mail to [email protected] or call [phone] and let us know the nature of your request and your contact information. Please include the job requisition number in your message.