Sr. Director, Medical Affairs, Neuromuscular Team

ITF Therapeutics; Concord (MA); On-site; USD 290,000 - 320,000; Full time

Job summary

ITF Therapeutics LLC is seeking a Senior Director of Medical Affairs, Neuromuscular, to lead the US medical strategy for givinostat in Duchenne muscular dystrophy. The role focuses on external medical engagement, evidence generation, and cross-functional collaboration to advance late-stage programs.

The ideal candidate has 10+ years in US Medical Affairs, leadership experience, and strong expertise in neuromuscular disorders, regulatory standards, and medical governance.

Qualifications

• Advanced degree in medicine, pharmacy, or related field.
• 10+ years in US Medical Affairs within pharma/biotech.
• Leadership of cross-functional medical teams including MSLs.
• Experience in rare diseases, neurology, or neuromuscular disorders.
• Deep knowledge of US regulatory and pharmacovigilance standards.
• Ability to build and lead teams in a matrixed organization.

Responsibilities

• Execute the US Neurometabolic Medical Affairs strategy aligned with corporate objectives and product lifecycle needs.
• Oversee US medical plans for Duvyzat, ensuring integration of regulatory, clinical, commercial and global medical perspectives.
• Lead the US Neuromuscular Medical Affairs team, including MSLs.
• Oversee medical education, scientific exchange, and non-registrational evidence-generation initiatives.
• Act as a strategic thought partner across Medical Affairs, R&D, and commercial teams.
• Provide medical and scientific support for late-stage clinical development programs, ensuring alignment with business and regulatory strategies.
• Support training and development of internal teams on product science and disease education.
• Implement right-sized systems and processes to optimize effectiveness of the medical affairs neurometabolic organization.
• Establish and maintain strong, trusted relationships with external medical experts, academic institutions, and medical societies.
• Oversee a comprehensive medical KOL engagement and insights-generation strategy.
• Localize medical information and publication resources.
• Develop medical governance frameworks to maintain high ethical and compliance standards in all engagements.

Skills

Cross-functional leadership

MSL leadership

Medical affairs strategy

KOL engagement

Scientific communications

Regulatory knowledge

Education

MD/PhD/PharmD

Job description

Reports to: VP, US Medical Affairs & Patient Advocacy

About This Role:

The Senior Director, Medical Affairs, Neuromuscular Team will lead the development and execution of the US medical strategy for givinostat in Duchenne muscular dystrophy. The qualified candidate will serve as a key medical representative in the US, supporting external medical expert engagement and development, communication and evidence generation strategy, and cross-functional collaboration.

What You’ll Do:

• Be responsible for execution of the US Neurometabolic Medical Affairs strategy aligned with corporate objectives and product lifecycle needs.
• Implement and oversee the execution of US medical plans for Duvyzat, ensuring integration of regulatory, clinical, commercial and global medical perspectives.
• Lead and development the U.S. Neuromuscular Medical Affairs team, including Medical Science Liaisons (MSLs).
• Oversee the execution of medical education, scientific exchange, and non-registrational evidence-generation initiatives.
• Act as a strategic thought partner across Medical Affairs, R&D, and commercial teams.
• Provide medical and scientific support for late-stage clinical development programs, ensuring alignment with business and regulatory strategies.
• Support training and development of internal teams on product science and disease education.
• Implement right-sized systems and processes to optimize effectiveness of the medical affairs neurometabolic organization
• Establish and maintain strong, trusted relationships with external medical experts, academic institutions, and medical societies.
• Oversee a comprehensive medical KOL engagement and insights-generation strategy.
• Localize medical information and publication resources.
• Develop medical governance frameworks to maintain high ethical and compliance standards in all engagements.

Required Skills:

• Advanced degree required (PharmD, MD, or PhD; PharmD strongly preferred).
• Minimum 10 years of progressive experience in U.S. Medical Affairs within the pharmaceutical or biotechnology industry.
• Prior leadership of cross-functional medical teams, including MSLs and medical communications.
• Experience in rare diseases, neurology, or neuromuscular disorders is strongly preferred.
• Deep knowledge of U.S. medical, regulatory, and pharmacovigilance standards.
• Demonstrated ability to work in a fast-paced, evolving environment and to build highly effective and accountable teams from the ground up.
• Experience supporting an early marketed product.
• Collaborative and decisive leader with a proven ability to navigate and contribute effectively within a matrixed organization.
• Exceptional interpersonal skills with a demonstrated ability to build strong relationships with both internal stakeholders and external partners.

Additional Information:

The base compensation range for this role is: $290,000 - $320,000. Compensation is determined through an analytical approach utilizing a combination of factors including, but not limited to, relevant skills & experience, job location, and internal equity.