Sr. Director, Cloud and Infrastructure Transformation
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Job summary
Pfizer is seeking a Senior Director of Cloud & Infrastructure Transformation to define the future-state strategy and execute enterprise-scale initiatives across cloud, networking, and data centers. You will guide architecture decisions, set engineering standards, and drive resilient, secure platforms at scale.
You will lead senior leaders across multiple domains, partner with stakeholders, and influence global transformation programs while delivering measurable business value in a highly
Qualifications
- Bachelor's degree in CS/CE/IT or related discipline.
- 12+ years in cloud, infrastructure or platform engineering leadership.
- Proven record leading enterprise-scale cloud transformations.
- Deep expertise in public cloud platforms (AWS, Azure, GCP) and production environments.
- Strong architecture review, credibility, and influence across teams.
- Experience leading Directors, Senior Managers, Architects and senior tech leaders.
Responsibilities
- Define and execute multi-year cloud and infra transformation strategy.
- Lead modernization across multi-cloud, AI platforms, and data center evolution.
- Serve as senior technical authority on architecture, security, and resiliency.
- Influence engineering standards, operating models, and roadmaps.
- Build partnerships across Digital, Security, Research, and Business units.
- Grow and manage high-performing teams and leaders.
Skills
Education
Tools
Job description
At the heart of Pfizer's Digital transformation sits Infrastructure & Cloud, enabling modern cloud platforms and engineering capabilities that accelerate scientific discovery, empower researchers, and improve patient outcomes worldwide.
Pfizer is seeking a highly accomplished technology leader who combines enterprise-scale strategic thinking with deep technical expertise in cloud, infrastructure, networking, and platform engineering. This role will shape the future of Pfizer's cloud and infrastructure ecosystem, enabling AI/ML-powered research, advanced analytics, and next-generation digital capabilities that support breakthrough science and drug discovery.
The successful candidate will be equally comfortable discussing business strategy with executive leadership, guiding large-scale transformation initiatives, and engaging directly with architects and engineers on critical technical decisions. This is a leadership role for someone who has not only led transformation programs but has personally helped design, build, and scale modern cloud platforms and infrastructure capabilities.
At Pfizer, your work will directly contribute to the technologies that enable scientists to accelerate research, unlock insights from complex data, and develop innovative medicines for patients around the world.
Pfizer seeks individuals who are highly self-motivated, intellectually curious, collaborative, and committed to continuous learning and growth.
The Senior Director, Cloud & Infrastructure Transformation serves as both a strategic technology executive and a technical thought leader for Pfizer's cloud and infrastructure landscape. This leader will define future-state infrastructure strategy while ensuring the successful execution of complex, enterprise-scale initiatives spanning cloud, networking, data center modernization, platform engineering, and AI infrastructure.
You will lead a team of senior leaders, architects, and engineering organizations while helping establish the technology vision, engineering standards, and operating models required to support Pfizer's digital future.
You will be expected to drive business outcomes through technology strategy while maintaining the technical depth and credibility necessary to guide architecture decisions, challenge assumptions, and ensure engineering excellence.
- Define and execute Pfizer's multi-year cloud and infrastructure transformation strategy, aligning technology investments with business and scientific priorities.
- Lead enterprise-wide modernization initiatives spanning multi-cloud environments, AI/ML platforms, network transformation, infrastructure automation, and data center evolution.
- Serve as a senior technical authority, providing guidance on architecture, platform engineering, cloud operations, resiliency, security, and infrastructure modernization.
- Partner with architects and engineering leaders to evaluate and influence critical technology decisions, ensuring scalable, secure, and operationally resilient solutions.
- Drive adoption of cloud-native architectures, Infrastructure as Code, automation, observability, DevOps, and Site Reliability Engineering practices.
- Establish technology roadmaps and engineering standards that support innovation, operational excellence, and regulatory compliance.
- Build strong partnerships across Digital, Security, Research, and Business organizations to accelerate enterprise transformation initiatives.
- Lead and develop high-performing teams of Directors, Senior Managers, and technical leaders while cultivating a culture of innovation, accountability, and technical excellence. Mainly influencing to start, followed by a larger team over time.
- Influence senior executive stakeholders and drive alignment across a complex, global, matrixed organization.
- Evaluate emerging technologies and industry trends to identify opportunities that improve Pfizer's technology capabilities and business outcomes.
- Balance strategic priorities, execution risks, operational demands, and technical considerations to drive sustainable transformation at scale.
Candidates should demonstrate a breadth of leadership experiences and capabilities, including:
- Influencing executive leaders, peers, and technical teams to achieve enterprise outcomes.
- Building organizational capability and developing future technology leaders.
- Creating an environment that promotes innovation, accountability, collaboration, and continuous improvement.
- Leading through ambiguity and driving execution in highly complex environments.
- Translating technology strategy into measurable business impact.
- Establishing credibility with both senior executives and highly technical engineering teams.
- Bachelor's degree in Computer Science, Computer Engineering, Information Technology, or related discipline.
- 12+ years of progressive leadership experience in cloud, infrastructure, networking, platform engineering, or related technology functions.
- Demonstrated success leading large-scale cloud and infrastructure transformation programs at enterprise scale.
- Deep expertise in public cloud platforms (AWS, Azure, and/or GCP), with a proven history of designing, building, and operating production environments supporting critical business workloads.
- Strong technical foundation spanning cloud architecture, networking, platform engineering, infrastructure operations, automation, and security.
- Demonstrated ability to engage in architecture reviews, challenge technical design decisions, and influence engineering standards through technical expertise and credibility.
- Experience leading organizations responsible for cloud engineering, platform engineering, infrastructure automation, architecture, operations, and reliability.
- Proven success developing and leading senior technology leaders, including Senior Managers, Directors, and Architects.
- Extensive experience driving results through influence across business, security, engineering, and executive stakeholder groups.
- Expertise in cloud-native architectures, Infrastructure as Code (Terraform/OpenTofu), automation, DevOps, observability, resiliency engineering, and modern operating models.
- Strong understanding of cybersecurity, compliance, and risk management practices within large enterprise environments.
- Exceptional communication skills with the ability to translate complex technical concepts into business-focused recommendations.
- Proven ability to simultaneously lead strategic planning and execution across multiple complex initiatives.
- Experience building or enabling AI/ML infrastructure, advanced analytics platforms, or high-performance computing environments.
- Experience supporting research, scientific computing, or large-scale data science workloads.
- Pharmaceutical, biotechnology, healthcare, or other highly regulated industry experience.
- Advanced degree in Computer Science, Engineering, Technology Management, or Business Administration.
- Industry certifications in cloud architecture, engineering, security, or infrastructure platforms.
- Experience leading global organizations across multiple regions, cultures, and time zones.
- Experience with enterprise-scale migrations, data center exits, platform modernization initiatives, or mergers and acquisitions.
- Demonstrated success driving technology transformation through both strategic vision and deep technical leadership.
The ideal candidate is a technology strategist and engineer at heart. They have built credibility through hands-on technical leadership, can engage deeply in architectural discussions, and have successfully led large-scale transformation efforts that delivered measurable business value. They are equally effective influencing executive stakeholders, mentoring technical leaders, and driving execution across complex enterprise environments.
Last day to apply: 9/7/2026
Work location assignment: Hybrid - onsite at NY Headquarters an average of 2.5 days per week or as the business requires
10-20% Travel
The annual base salary for this position ranges from $214,900.00 to $358,100.00. In addition, this position is eligible for participation in Pfizer’s Global Performance Plan with a bonus target of 22.5% of the base salary and eligibility to participate in our share based long term incentive program. We offer comprehensive and generous benefits and programs to help our colleagues lead healthy lives and to support each of life’s moments. Benefits offered include a 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution, paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage. Learn more at Pfizer Candidate Site – U.S. Benefits | (uscandidates.mypfizerbenefits.com). Pfizer compensation structures and benefit packages are aligned based on the location of hire. The United States salary range provided does not apply to Tampa, FL or any location outside of the United States.
Relocation assistance may be available based on business needs and/or eligibility.
Candidates must be authorized to be employed in the U.S. by any employer.
U.S. work visa sponsorship (such as TN, O-1, H-1B, etc.) is not available for this role now or in the future.
Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations. These laws and regulations require Pfizer to provide government agencies with information such as a health care provider’s name, address and the type of payments or other value received, generally for public disclosure. Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act. Therefore, if you are a licensed physician who incurs recruiting expenses as a result of interviewing with Pfizer that we pay or reimburse, your name, address and the amount of payments made currently will be reported to the government. If you have questions regarding this matter, please do not hesitate to contact your Talent Acquisition representative.
Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer. This position requires permanent work authorization in the United States.
Pfizer endeavors to make www.pfizer.com/careersaccessible to all users. If you would like to contact us regarding the accessibility of our website or need assistance completing the application process and/or interviewing, please email disabilityrecruitment@pfizer.com. This is to be used solely for accommodation requests with respect to the accessibility of our website, online application process and/or interviewing. Requests for any other reason will not be returned.
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