Sr. Clinical Data Manager

ACL Digital; King of Prussia (PA); Hybrid; USD 110,000 - 140,000; Full time

Job summary

ACL Digital is seeking a Clinical Data Manager in the United States (King of Prussia, PA area) to lead the data management lifecycle for clinical trials. You will oversee start-up through database lock, ensure data integrity, and maintain regulatory compliance across studies.

The role involves designing DM plans, configuring EDC systems, generating data listings, and collaborating with study teams to resolve data‑related issues while adhering to CDISC standards.

Qualifications

• Experience in clinical data management or clinical trial data handling.

Responsibilities

• Oversee end-to-end Clinical Trial Data Management from start-up to database lock.
• Ensure data quality, accuracy, and regulatory compliance (GCP/CDISC).
• Develop data management plans, data collection strategies, and documentation for sites.
• Configure and validate EDC systems and CRFs.
• Generate data listings and conduct data cleaning, discrepancy management, and validation.
• Collaborate with cross-functional teams to resolve data-related issues and align with study protocols.

Job description

• Oversee the entire Clinical Trial Data Management process, from start-up to database lock, ensuring data quality, accuracy, and compliance with regulations
• Contribute to the development of project timelines and resource planning. Develop training materials and documentation for internal users and site personnel
• Design and Implement detailed data management plans (DMPs) and data collection strategies that covers coding, data transfer, discrepancy management, workflow, reporting, and data validation.
• Develop, configure, and verify clinical databases and electronic data capture (EDC) systems, including case report forms (CRFs).
• Generate and review Data cleaning listings such as offline listings, medical coding listings and missing pages reports. o Conduct data entry, cleaning, validation checks, and resolve discrepancies to uphold data accuracy, completeness, and compliance with quality standards.
• Collaborate with cross-functional study teams to resolve data-related issues, integrate feedback, and align data management practices with study protocols. o Adhere to Good Clinical Practice (GCP) and CDISC standards.

• Oversee the entire Clinical Trial Data Management process, from start-up to database lock, ensuring data quality, accuracy, and compliance with regulations
• Contribute to the development of project timelines and resource planning. Develop training materials and documentation for internal users and site personnel
• Design and Implement detailed data management plans (DMPs) and data collection strategies that covers coding, data transfer, discrepancy management, workflow, reporting, and data validation.
• Develop, configure, and verify clinical databases and electronic data capture (EDC) systems, including case report forms (CRFs).
• Generate and review Data cleaning listings such as offline listings, medical coding listings and missing pages reports. o Conduct data entry, cleaning, validation checks, and resolve discrepancies to uphold data accuracy, completeness, and compliance with quality standards.
• Collaborate with cross-functional study teams to resolve data-related issues, integrate feedback, and align data management practices with study protocols. o Adhere to Good Clinical Practice (GCP) and CDISC standards.

Note: no travel is required for this role though remote work from "various worksites" permitted.