Sr Biochemistry Scientist

Illumina; Madison (WI); On-site; USD 91,000 - 137,000; Full time

Job summary

Illumina in Madison is seeking a Senior Biochemistry Scientist to join our Test Method Engineering team. You will drive development, optimization, characterization, and transfer of biochemical and enzymatic assays supporting manufacturing, using state-of-the-art instruments.

Working in a cGMP lab, you will train others on key platforms, perform data analysis and reports, and collaborate with Quality Control, Manufacturing, QA, and partners worldwide.

Qualifications

• 6+ years of industry lab experience in biotechnology, biomedical, biochemical or pharmaceutical industry.
• Advanced HPLC experience with proficiency in method development/optimization, and assay validation.
• Demonstrated ability to learn quickly and take initiative.
• Demonstrated expertise in enzymatic assays and biochemical characterization techniques.

Responsibilities

• Develop, optimize, characterize, and transfer biochemical and enzymatic assays to support manufacturing operations.
• Operate, maintain, and train others on key lab equipment including HPLCs, PCRs, microplate readers, and Tape Station units.
• Prepare method transfer documentation and lead transfer activities to internal/external labs.
• Perform data processing, statistical evaluation, and interpretation of results; prepare technical reports and SOPs.
• Collaborate with Quality Control, Manufacturing, QA, Process Development, and partner sites.
• Work both independently and as part of a scientific team; participate in meetings and initiatives.
• Edit and revise SOPs and area work instructions.
• Investigate and resolve technical issues; contribute to continuous improvement and sustaining activities.

Skills

Enzymatic assays

Biochemical characterization

Cross-functional collaboration

Problem-solving

MS Office proficiency

Education

Bachelor’s degree in Biochemistry/Chemistry/Biology

Master’s degree (preferred)

PhD (strongly preferred)

Tools

Fragment analyzers

Microplate readers

HPLC

PCR machines

Tape Station

Job description

What if the work you did every day could impact the lives of people you know? Or all of humanity?

At Illumina, we are expanding access to genomic technology to realize health equity for billions of people around the world. Our efforts enable life-changing discoveries that are transforming human health through the early detection and diagnosis of diseases and new treatment options for patients.

Working at Illumina means being part of something bigger than yourself. Every person, in every role, has the opportunity to make a difference. Surrounded by extraordinary people, inspiring leaders, and world changing projects, you will do more and become more than you ever thought possible.

You are the Senior Biochemistry Scientist Illumina is looking for in joining our Test Method Engineering team! In your future role at the Madison site of the global front-runner in genetic sequencing, you will be one of a group of scientists who produce the fuel for Illumina’s sequencing, which is used in the study of genetic variation and function in realms from cancer research to agriculture.

As part of a diverse, self-directed team, you will be responsible for driving method development and validation activities in a cGMP laboratory for analysis of a broad range of enzymes using-state-of-art processes and equipment. You will also contribute to team driven improvement initiatives, engage in a curious and science-focused environment, and collaborate closely with cross-functional teams. We want your talent, genuine curiosity about applied science, enthusiasm for creative problem-solving, and drive to get things done.

Job Duties Include, But Are Not Limited To

• Responsible for the development, optimization, characterization, and transfer of biochemical and enzymatic assays to support manufacturing operations.
• Independently operate, maintain, and train others on key laboratory equipment platforms including fragment analyzers, microplate readers, HPLCs, PCRs, and Tape Station units.
• Prepare method transfer documentation and lead method transfer activities to internal and external laboratories, ensuring reproducibility and compliance with quality standards.
• Perform data processing, statistical evaluation, and interpretation of experimental results. Prepare technical reports, presentations, and documentation in accordance with internal GMP quality systems
• Work closely with Quality Control, Manufacturing, Quality Assurance, Process Development, and global partner sites to support project execution.
• Work independently and collaboratively as part of a scientific team and participate in team meetings and initiatives.
• Edit and revise area work instructions and standard operating procedures (SOPs)
• Contribute to investigation and resolution of technical issues.
• Assist with continuous improvement and sustaining activities.
• Perform analyses of processes, identify gaps and deficiencies, and proactively propose practical, data driven solutions.
• Maintain organization and inventory of lab supplies, equipment, and reagents.
• Ability to lift 40 lbs. in weight and stand for periods of time during the manufacturing processes.
• Other duties that may be requested by management.

Requirements

• 6+ years of industry relevant laboratory experience in biotechnology, biomedical, biochemical or pharmaceutical industry.
• Advanced HPLC experience with proficiency in method development/optimization, and assay validation.
• Demonstrated ability to learn quickly and take initiative.
• Demonstrated expertise in enzymatic assays and biochemical characterization techniques.
• Excellent laboratory, organizational, and research skills.
• Demonstrated ability to work on a diverse team.
• Effective communicator with the ability to interface across functions.
• Experienced in problem-solving and reasoning skills.
• Proficient in Microsoft Word, PowerPoint & Excel.

Education

• Typically requires a degree in biochemistry, chemistry, biology, or related field. Bachelor’s degree with a minimum of 6+ years of relevant industry experience or Master’s degree with a minimum of 4+ years of relevant industry experience or PhD with 2+years of relevant industry experience preferred.

The estimated base salary range for the Sr Biochemistry Scientist role based in the United States of America is: $91,100 - $136,700. Should the level or location of the role change during the hiring process, the applicable base pay range may be updated accordingly. The range reflects long‑term growth in the role; therefore, most candidates are hired between the minimum and middle of the range. Placement depends on experience, skills, location, and internal equity. Additionally, all employees are eligible for one of our variable cash programs (bonus or commission) and eligible roles may receive equity as part of the compensation package. We offer a wide range of benefits as innovative as our work, including access to genomics sequencing, family planning, health/dental/vision, retirement benefits, and paid time off.

We are a company deeply rooted in belonging, promoting an inclusive environment where employees feel valued and empowered to contribute to our mission. Built on a strong foundation, Illumina has always prioritized openness, collaboration, and seeking alternative perspectives to propel innovation in genomics. We are proud to confirm a zero-net gap in pay, regardless of gender, ethnicity, or race. We also have several Employee Resource Groups (ERG) that deliver career development experiences, increase cultural awareness, and offer opportunities to engage in social responsibility. We are proud to be an equal opportunity employer committed to providing employment opportunity regardless of sex, race, creed, color, gender, religion, marital status, domestic partner status, age, national origin or ancestry, physical or mental disability, medical condition, sexual orientation, pregnancy, military or veteran status, citizenship status, and genetic information.

Illumina conducts background checks on applicants for whom a conditional offer of employment has been made. Qualified applicants with arrest or conviction records will be considered for employment in accordance with applicable local, state, and federal laws. Background check results may potentially result in the withdrawal of a conditional offer of employment. The background check process and any decisions made as a result shall be made in accordance with all applicable local, state, and federal laws. Illumina prohibits the use of generative artificial intelligence (AI) in the application and interview process. If you require accommodation to complete the application or interview process, please contact [e-mail]. To learn more, visit: https://www.dol.gov/ofccp/regs/compliance/posters/pdf/eeopost.pdf. The position will be posted until a final candidate is selected or the requisition has a sufficient number of qualified applicants. This role is not eligible for visa sponsorship.