Software Engineer, Applications – Scientific Development Solutions

Jobtailor

San Francisco (CA)

On-site

USD 180,000 - 240,000

Full time

14 days+

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Job summary

Benchling is seeking a Senior Software Engineer to act as the senior technical authority for Study Lifecycle and Process Execution teams in San Francisco. You will architect and implement solutions for complex scientific workflows in regulated environments, lead multi-quarter initiatives, and guide engineering direction with strong mentoring across the team.

You will own end-to-end delivery from planning through deployment, with a focus on scalable backend systems, APIs, and a capable full-stack

Qualifications

8+ years of professional software engineering experience with increasing scope and impact.
Experience as a technical lead on significant multi-quarter projects.
Strong backend systems and APIs for cloud-based web applications; full-stack capability with React frontend and Python backend.
Proven ability to design scalable architectures aligned with business needs.
Mentor and develop engineers, raise testing and maintainability standards.

Responsibilities

Serve as senior technical authority for Study Lifecycle and Process Execution teams; drive design and development across studies and workflows.
Architect and implement end-to-end solutions for scientific workflows in regulated environments (GLP/GMP).
Lead large, multi-quarter initiatives and translate requirements into concrete delivery milestones.
Provide architectural guidance, code reviews, and mentorship across teams; influence engineering direction.
Partner with product management and design to translate customer needs into technical solutions.
Explore use of AI/LLMs to improve lab operations and analysis workflows.
Own delivery from planning to deployment and monitoring; scale the team and processes.

Skills

Backend Systems Development

API Design & Implementation

Technical Leadership

Full-Stack Development

React Development

Python Programming

PostgreSQL

Code Review

Tools

React

Python

PostgreSQL

Job description

Serve as the senior technical authority for the Study Lifecycle and Process Execution teams, driving the design and development of systems that advance Benchling's product and business goals across studies, workflows, procedures, and bioprocess/bioanalytical workflows.
Independently architect and implement solutions to complex, open-ended problems — from system architecture to backend models and APIs to rich frontend UI — for scientific workflows used in regulated (GLP/GMP) environments.
Lead large, multi-quarter initiatives: break down ambiguous scientific and regulatory requirements into concrete technical plans and iterative delivery milestones.
Use technical decision-making as a tool of engineering strategy — knowing when to leverage existing platform capabilities, when to take on technical debt deliberately, and when to preserve optionality for the long term.
Act as a force multiplier across the Applications division: help set engineering direction, raise standards for quality and architecture, and influence technical choices beyond your immediate teams.
Provide technical leadership through code review, architectural guidance, and mentorship of engineers across all experience levels.
Partner closely with product management, design, and cross-functional stakeholders to translate customer and scientific needs into technical solutions.
Explore and evaluate opportunities to leverage AI and LLMs to make lab operations, SOP execution, and time-series analysis faster and more reliable for scientists.
Own end-to-end delivery of critical features — from planning and development through deployment, maintenance, and monitoring.
Help build and scale the team by improving our tooling, engineering processes, interviewing, hiring, and onboarding.

Requirements

8+ years of professional software engineering experience, with a demonstrated progression of increasing scope and impact.
Experience as a technical lead on significant projects involving multiple engineers across multiple quarters.
Strong experience building backend systems and APIs for cloud-based web applications, plus the ability to build full-stack when needed. Our stack is a comprehensive React frontend and a Python backend on a predominantly relational data model in Postgres; direct experience is appreciated but not required if you can pick it up quickly.
Proven ability to design scalable, robust architectures that align with business requirements and long-term maintainability.
Track record of independently scoping and driving initiative-level work whose impact spans multiple teams and shapes an entire product area or division.
Excellent written and verbal communication skills — able to produce clear technical designs and use influence rooted in technical expertise to align other engineers on an implementation strategy.
Demonstrated ability to mentor and develop other engineers, raising the team's bar in areas such as testing, performance, and maintainability.
Interest in learning about life sciences. Prior biotech knowledge is appreciated but not required; enthusiasm to learn is essential. (Experience with regulated, GLP/GMP, or laboratory/manufacturing software is a plus.)

Core Competencies

Demonstrates expertise in architecting and implementing scalable backend systems and APIs for cloud-based applications, with a strong focus on technical leadership and mentoring. Capable of translating complex scientific and regulatory requirements into actionable technical solutions while fostering collaboration across cross-functional teams.

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