Software Engineer

LatchBio; San Francisco (CA); On-site; USD 180,000 - 250,000; Full time

Benefits offered by this job

Unlimited PTO (truly)

Waterfront office in China Basin, San 

Free lunch and dinner

100% premium covered on Blue Shield's}

Job summary

LatchBio in San Francisco is seeking software engineers to build the infrastructure powering our benchmarking platform for biology AI. You will work on agent infrastructure, model benchmarking at scale, full stack web development, and tooling optimization, within a small team.

You’ll own product areas, collaborate with scientists and frontend/backend engineers, and contribute to scaling the internal benchmarking platform while delivering features that improve quality and speed.

Qualifications

• Interest in computer systems and distributed architectures.
• Designed and shipped products that people love.
• Ability to apply systems engineering to tooling and data platforms.

Responsibilities

• Work on agent infrastructure and model benchmarking at scale.
• Develop full-stack features for the benchmarking platform.
• Collaborate with scientists and frontend/backend engineers to meet customer requirements.

Skills

Distributed systems

Full stack development

Tools

PostgreSQL

Amazon S3

Job description

About LatchBio

We build the benchmarks that test whether frontier AI can actually do computational biology. Pharma, biotech, and solution providers rely on benchmarks.bio to evaluate and improve their AI systems - and we're just getting started.

We released the first rigorous benchmark suites for biology agents. They contain hundreds of real-world problems drawn directly from industry workflows. Our research shows that harness design - the tools, prompts, and control flow around a model - moves outcomes as much as swapping the base model itself. This insight is reshaping how frontier labs think about building with AI.

We've grown revenue 6x in the past 12 months. We have a repeatable sales process and deep partnerships with 10X Genomics, Vizgen, Takara Bio, and AtlasXOmics. More importantly: we have more demand than we can meet. That's why we're scaling rapidly across engineering. We're building benchmarks across omics, therapeutics, and surveillance. We need engineers to build the infrastructure that powers our benchmarking pipeline - data ingestion, eval design, grading systems, and infrastructure. Work with scientists and frontier models. Ship fast.

Here is a sample of engineering products we work on

• Agent harness integrated with bio first tooling such as an in-house h5ad and genomics viewer
• Distributed file-system with metadata on Postgres and blobs on S3
• Cluster orchestrator designed to accept compute nodes from anywhere on the internet
• Reactive Python-based notebooks for data analysis and visualization
• Benchmarking harness with automated QC processes to validate and probe model failure cases

About this role

You will be working on problems in software including but not limited to agent infrastructure and systems, model benchmarking at scale, full stack web development, developer and user experience, and process optimization. You will work on a small team and have control over the direction you take and problems you tackle. You may work on scaling and improving a large scale internal benchmarking platform, planning and delivering features to improve quality and speed, and supporting ever evolving customer requirements and difficult computational tasks. Where appropriate, your work may dip into research for agentic biology.

Signs of strong fit

• Interest in computer systems and their inner workings e.g. compilers, operating systems, databases, distributed systems, programming language theory
• Designed and shipped products that people love
• Ability to apply process or systems engineering approach to tooling and data systems

How we work

We care about output and let people optimize their work in a way that works for them. Our engineering team is in-person in San Francisco. We run a daily standup where engineers talk through technical challenges and stay aligned on what matters most. You will own a product area and execute, working closely with seasoned Latch engineers, product managers, and designers. Mentorship happens through code review and working through hard problems together.

Our charter and continued mission is to accelerate biological science so that humanity can benefit from better bioengineering, whether that be medical technology, farming, or environmental conservation. If you are motivated to work on these problems surrounded by like-minded people, LatchBio may be a great fit for you.

Who you'll work with

Engineering: Aidan, Ryan, Max, Anirudh, Joel, Tim

Product: Hannah, Nathan

Founders & Chief of Staff: Alfredo, Kyle, Kenny, Jordan

Hiring process

Our process is typically completed within two weeks.

Round 1: Introduction - Greg (Technical Recruiter)

Round 2: Live Coding Project (HackerRank)

Round 3: Technical - Latch Engineer

Round 4: Cultural - Aidan

Round 5: Final/ 1-Day Paid Onsite Project

Offer

Compensation & Benefits

• $180k–$250k/yr
• Equity
• Unlimited PTO (truly)
• Waterfront office in China Basin, San Francisco
• Free lunch and dinner
• 100% premium covered on Blue Shield's platinum health plan ($0 premium, $0 deductible)
• 401(k) plan options
• Work visa sponsorship
• Company-sponsored professional development

Learn More

• Agent.bio — The AI agent for biology
• Benchmarks.bio — The benchmarks for biology agents
• Console.latch.bio — The harness for agentic data analysis