Small Molecule Process Development Engineer – Synthetic API Scale-Up & Modeling - (JP15784)

3key Consulting, Inc.; Cambridge (MA); On-site; USD 117,482,000 - 131,809,000; Full time

Job summary

3 Key Consulting is seeking a Small Molecule Process Development Engineer for a contract role with a leading global biopharmaceutical company in Cambridge, MA. You will partner with a multi-functional team to develop and optimize synthetic unit operations for technology transfer and commercial support, including experimental design, data analysis, and equipment commissioning.

The position requires a practical background in chemical engineering and experience in process development for

Qualifications

• Academic background in Chemical Engineering.
• Experience in a Process Development/Process Engineering environment for synthetics/small molecules.
• Experience building and utilizing first-principles models (reaction kinetics, mass transfer, separations) with several modeling platforms.

Responsibilities

• Evaluate, select and execute standard experimental, modeling and engineering techniques for process optimization and scale-up of synthetic APIs in state-of-the-art facilities.
• Initiate and complete technical tasks in lab and pilot plants.
• Author documents for process understanding, transfer, risk assessment and development/characterization.
• Serve as a technical expert for equipment or systems troubleshooting operations.
• Suggest problem resolutions, provide troubleshooting guidance and recommend process improvements.
• Apply engineering principles and design of experiments to solve processing issues and evaluate opportunities for optimization.
• Communicate and collaborate with Manufacturing, Process Development, and Quality departments.

Skills

Chemical Engineering

Process Development

Modeling platforms

Education

Master's degree in Chemical Engineering

Bachelor's degree in Chemical Engineering

Job description

Small Molecule Process Development Engineer – Synthetic API Scale-Up & Modeling - (JP15784)

• Cambridge, MA
• Biotech/Pharmaceutical

Job Title: Small Molecule Process Development Engineer – Synthetic API Scale-Up & Modeling - (JP15784)

Location: Cambridge, MA. 02138

Employment Type: Contract

Business Unit: DST Synthetics B

Duration: 2+ year (with likely extensions and/or conversion to permanent)

Posting Date: 08/27/26

Pay Rate: $41 - $46/hour W2

Notes: Only qualified candidates need apply. 100% Onsite - Cambridge MA

3 Key Consulting is hiring a Small Molecule Process Development Engineerfor a consulting engagement with our direct client, a leading global biopharmaceutical company.

Job Description:

The Engineer will partner with a multi-functional group of engineers and scientists through the process development cycle at client to develop and optimize synthetic unit operations aligned for the intended phase of technology transfer and commercial support. This includes experimental design and execution, data analysis, process risk analysis, process characterization, facility fit assessment, and support of kilo lab operations during process execution and equipment commissioning.

Why is the Position Open?

Supplement additional workload on team

Top Must Have Skills:

• 1. Academic background in Chemical Engineering.
• 2. Experience in a Process Development/Process Engineering environment for synthetics / small molecule.
• 3. Experience building and utilizing first principal models (reaction kinetics, mass transfer, separations, distillations, isolations, drying, and hydrodynamics) with proficiency across several modeling platforms.

Day to Day Responsibilities:

• Evaluate, select and execute standard experimental, modeling and engineering techniques for process optimization, characterization, and scale up of synthetic active pharmaceutical ingredients in state-of-the-art facilities.
• Initiate and complete technical tasks in lab, kilo/pilot plant
• Author documents for process understanding, transfer, risk assessment, facility fit, and development/characterization.
• Function as a technical expert to equipment or systems regarding troubleshooting operations.
• Suggest problem resolution, provide troubleshooting guidance and recommend process improvements.
• Apply engineering principles and statistical analysis, including design of experiments, in order to solve processing issues and evaluate opportunities for process improvements.
• Communicate and collaborate with Manufacturing, Process Development, and Quality departments.
• Contribute to key regulatory and quality activities such as non-conformance, process performance qualification and continued process verification.

Basic Qualifications:

• Master degree OR Bachelor degree and 2 years of experience OR Associate degree and 6 years of experience OR High school diploma / GED and 8 years of experience

Interview process:

One phone screen with Hiring Manager. Two additional panel interviews.