Site-Reliability Engineer, Application Operations

Scorpion Therapeutics; Irving (TX); On-site; USD 120,000 - 180,000; Full time

Job summary

Scorpion Therapeutics is seeking an experienced SRE/Production Operations engineer to manage on-call for production incidents in FDA-regulated clinical applications. You will implement runbooks, monitor SLOs, assist with releases, and contribute to automation and incident reviews.

The role requires 5+ years in SRE/production ops, on-call experience for Tier 1 systems, and familiarity with privileged-action controls. On-call work includes after-hours; travel may be required.

Qualifications

• BS in CS/IS/SE or related field, or equivalent experience.
• 5+ years in SRE/production ops/DevOps/platform engineering (production support).
• 2+ years on-call primary responder for Tier 1/business-critical systems.
• Experience executing production runbooks/maintenance/change procedures with privileged-action controls.
• Experience with production monitoring/alerting dashboards in an observability platform.
• Experience in post-incident review/blameless retrospectives.
• Hands-on use of AI coding assistants for operational automation.

Responsibilities

• Serve as primary on-call responder for production incidents; triage, elevate and remediate per runbooks.
• Execute approved production runbooks and maintenance scripts; document privileged actions for audits.
• Implement/maintain application instrumentation and monitor SLO budgets; escalate when budgets are at risk.
• Support releases: verify deployment health, monitor post-deploy behavior, rollback if needed.
• Participate in post-incident reviews; reconstruct timelines and drive remediation actions to closure.
• Maintain audit-ready access logs and privileged-action records.

Skills

SRE/DevOps

On-call responder

Monitoring/observability

Automation scripting

Post-incident reviews

Privileged-action controls

Education

BS in CS/IS/SE

Equivalent experience

Tools

Observability platform

Runbooks/playbooks

Job description

Responsibilities:

• Serve as primary responder in scheduled on-call for production incidents across SOX- and FDA-regulated clinical applications; triage, elevate and remediate per runbooks/incident playbooks.


• Execute approved production runbooks and maintenance scripts; document privileged actions for SOX ITGCs and FDA audit-trail requirements.


• Implement/maintain application-layer instrumentation (dashboards, alert thresholds, SLO monitors) and monitor SLO/error-budget consumption; **escalate** when budgets are at risk.


• Support releases/deployments: verify deployment health, monitor post-deploy behavior, and perform rollback when required.


• Participate in post-incident reviews: reconstruct timelines, identify contributing factors, and drive remediation action items to closure.


• Maintain audit-ready access logs, privileged-action records, and role-change documentation.


• Automate recurring operational work; track manual-intervention rate and reduce it by retiring runbook steps into automation.


• Author/update runbooks and known-issue documentation; improve operate discipline.


• Collaborate with application engineering to validate production fixes; contribute to on-call tooling and alert-quality improvements.


• Use AI coding assistants/agentic workflows for monitoring, triage, runbooks, and automation scripting (review as quality gate).

Required Qualifications:

• BS in CS/IS/SE or related, or equivalent experience.


• 5+ years in SRE/production ops/DevOps/platform engineering (production support).


• 2+ years on-call primary responder experience for Tier 1/business-critical systems.


• Experience executing production runbooks/maintenance/change procedures with privileged-action controls.


• Experience with production monitoring/alerting dashboards in an observability platform.


• Experience in post-incident review/blameless retrospectives.


• Hands-on use of AI coding assistants for operational automation.

Preferred Qualifications:

• Familiarity with SLO/error budgets and alerting design.


• Experience reducing toil via automation.


• Experience in SOX-controlled IT or CLIA/CAP-regulated environments.


• Cloud-native observability at the application instrumentation layer; telemetry/tracing/APM.


• Domain experience in clinical diagnostics/lab information systems/digital health.


• Familiarity with SAST/DAST and secure CI/CD; deployment pipelines/container orchestration/release automation.


• Relevant cloud/security certifications.

Physical/Other:

• Ability to sit/stand/work at a computer for extended periods.


• On-call includes required after-hours response (evenings/weekends); periodic travel may be required.