Service Engineer II, Screening Automation

Guardant Health, Inc.; Palo Alto (CA); Hybrid; USD 108,000 - 149,000; Full time

Job summary

Guardant Health, Inc. is seeking a Service Engineer II, Screening Automation in Palo Alto to install, maintain and repair advanced lab instruments including API, library prep systems, and NGS sequencers. You will ensure instrument uptime and quality documentation in a regulated environment.

The role requires hands-on technical skills, ability to learn new tech quickly, and strong communication to coordinate with internal teams and external vendors. Hybrid work model with onsite days.

Qualifications

• BS degree in engineering or a scientific discipline.
• 2–5 years of relevant field service experience.
• Experience operating and troubleshooting Hamilton Liquid Handlers, Illumina sequencers, Agilent Bravo platform/heads, Biotek MultiFlos, Precise robotic arm, centrifuges and other DNA quantification instruments.
• Experience authoring and executing PM, IQ, OQ, repair, and other service-related documentation.
• Experience working in CLIA and GMP regulated environments; strong cross-functional collaboration.

Responsibilities

• Install, maintain, repair, and qualify laboratory instruments (IOPQ) to maximize uptime.
• Monitor instrument metrics and coordinate with cross-functional teams.
• Prepare SOPs, checklists, and service bulletins.
• Provide after-hours and weekend support as needed.
• Communicate effectively with third-party service providers.

Education

BS degree in engineering or scientific discipline

Tools

Hamilton Liquid Handlers

Illumina Sequencers

Agilent Bravo platform/heads

Biotek MultiFlos

Precise robotic arm

centrifuges

Job description

Guardant Health is a leading precision oncology company focused on guarding wellness and giving every person more time free from cancer. Founded in 2012, Guardant® is transforming patient care and accelerating new cancer therapies by providing critical insights into what drives disease through its advanced blood and tissue tests, real-world data and AI analytics. Guardant tests help improve outcomes across all stages of care, including screening to find cancer early, monitoring for recurrence in early-stage cancer, and treatment selection for patients with advanced cancer. For more information, visit guardanthealth.com and follow the company on LinkedIn, X (Twitter) and Facebook.

As the Service Engineer II, Screening Automation, you are part of a dynamic team that supports the Guardant Health Shield Screening program at our Palo Alto site. This role will primarily work on a variety of laboratory instruments including Automated Plasma Isolation (API) and Library Preparation track systems, liquid handlers & NGS sequencers. You will be responsible for equipment installations, maintenance & repairs etc. You must be detail oriented, have experience working in a regulated environment (CLIA, CAP and FDA desirable), possess strong documentation skills (GDP) and strong communication skills, both written and verbal.

The annualized base salary ranges for the primary location and any additional locations are listed below. This range does not include benefits or, if applicable, bonus, commission, or equity. Each candidate’s compensation offer will be based on multiple factors including, but not limited to, geography, experience, education, job-related skills, job duties, and business need.

Primary Location: Palo Alto, CA

Primary Location Base Pay Range: $108,000 - $148,500

Other US Location(s) Base Pay Range: $91,800 - $126,225

If the role is performed in Colorado, the pay range for this job is: $97,200 - $133,650

Employee may be required to lift routine office supplies and use office equipment. Majority of the work is performed in a desk/office environment; however, there may be exposure to high noise levels, fumes, and biohazard material in the laboratory environment. Ability to sit for extended periods of time.

Hybrid Work Model:

This section is applicable to onsite employees who are eligible for hybrid work location as specified by management and related policies. Guardant has defined days for in‑person/onsite collaboration and work‑from‑home days for individual‑focused time. All U.S. employees who live within 50 miles of a Guardant facility will be required to be onsite on Mondays, Tuesdays, and Thursdays. We have found aligning our scheduled in‑office days allows our teams to do the best work and creates the focused thinking time our innovative work requires. At Guardant, our work model has created flexibility for better work‑life balance while keeping teams connected to advance our science for our patients.

Essential Duties and Responsibilities:

• Perform laboratory instrument installations, maintenance, repairs, and qualifications (IOPQ) to ensure the highest level of instrument reliability and up-time.
• Monitor instrument metrics and advocate serviceability within cross-functional teams.
• Responsible for instrument up-time and ensuring that service documentation meets Guardant Heath's Quality Management system.
• Evaluate equipment performance trends to propose long-term solutions as needed.
• Ability to quickly learn new technologies and disseminate information by developing SOPs, checklists, and service bulletins.
• Contribute to the management of the maintenance and calibration system.
• Help end-users troubleshoot issues.
• Provide service and support during normal business hours, as well as after hours and over weekends (as needed).
• Effectively communicate with third party service providers.

Qualifications

A BS degree in an engineering or scientific discipline with 2-5 years of relevant work experience. Experience operating and troubleshooting Hamilton Liquid Handlers, Illumina Sequencers, Agilent Bravo platform/heads, Biotek MultiFlos, Precise robotic arm, centrifuges and other DNA quantification instruments are required. Experience authoring and executing PM, IQ, OQ, repair, and other service-related documentation. Experience developing and leading training programs to provide knowledge-transfer to other engineers and lab personnel. Experience working within a CLIA and GMP regulated environment. Experience standardizing processes for scalability and sustainability. Ability to effectively communicate and collaborate with internal and external colleagues as well as customers from diverse scientific, engineering, operational, and regulatory disciplines. Liquid Handler programming experience is a plus. Robotics experience is a plus. Field service engineering experience is desirable. Ability to take part in an on-call rotation with after-hours and weekend responses (as needed). Strong communication skills (verbal and written). Ability to work effectively in a team environment and build strong working relationships High degree of initiative and self-motivation. Drive for continuous improvement. Experience with MS Office. AI & Digital Fluency Demonstrate curiosity, sound judgment, and the ability to critically evaluate and responsibly leverage AI-enabled tools in accordance with company policies, ethical standards, and regulatory requirements to improve the efficiency, effectiveness, and quality of work.

Accommodations and Background Screening

Guardant Health is committed to providing reasonable accommodations in our hiring processes for candidates with disabilities, long-term conditions, mental health conditions, or sincerely held religious beliefs. If you need support, please reach out to [e-mail]. A background screening including criminal history is required for this role. GH will consider qualified applicants with criminal arrest or conviction histories in a manner consistent with applicable law including but not limited to the LA County Fair Chance Policies and the Fair Chance Act (Gov. Code Section 12952).

Equal Opportunity Employment Statement

Guardant Health is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, or protected veteran status and will not be discriminated against on the basis of disability. All your information will be kept confidential according to EEO guidelines.

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If you like wild growth and working with happy, enthusiastic over‑achievers, you'll enjoy your career with us! Our Work Experience is the combination of everything that's unique about us: our culture, our core values, our company meetings, our commitment to sustainability, our recognition programs, but most importantly, it's our people.

Our employees are self-disciplined, hard working, curious, trustworthy, humble, and truthful. They make choices according to what is best for the team, they live for opportunities to collaborate and make a difference, and they make us the #1 Top Workplace in the area.

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