SERM Oncology Medical Director - Safety & Strategy Leader

GlaxoSmithKline; Upper Providence (Delaware County); Hybrid; USD 223,000 - 371,000; Full time

Benefits offered by this job

Health care

Retirement benefits

Paid holidays

Paid vacation

Parental and medical leave

Job summary

GlaxoSmithKline is seeking a medical safety leader in oncology to guide pharmacovigilance strategies across clinical development. You will analyze safety signals, engage with governance, and provide evidence-based recommendations to protect patient safety while shaping the safety profile of oncology medicines.

The role requires a medical degree with strong clinical judgment, extensive experience in pharmacovigilance, and the ability to lead cross‑functional teams in a global matrix environment.

Qualifications

• Medical degree with current GMC registration (or eligibility to practise in the UK) and relevant clinical experience.
• Completion of formal postgraduate clinical training (e.g., residency or specialty training)
• Significant experience in pharmacovigilance, drug safety, or medical affairs
• Demonstrated expertise in signal detection, evaluation, and risk management
• Strong understanding of clinical development and post‑marketing safety processes
• Experience working effectively in matrixed, cross‑functional environments
• Excellent written and verbal communication skills, including preparation of medical and regulatory documents
• Strong clinical judgement and the ability to deliver clear, evidence-based recommendations

Responsibilities

• Lead pharmacovigilance and risk management activities for assigned oncology assets and clinical trials.
• Define and drive strategy for the evaluation and management of safety issues across the clinical development lifecycle.
• Analyse and interpret clinical data, literature, and emerging evidence to identify and assess safety signals.
• Provide expert medical input into the safety components of global regulatory submissions.
• Apply sound clinical judgement to complex data sets to inform benefit‑risk decisions.
• Ensure timely escalation of safety concerns in line with governance processes.

Skills

Analytical thinking

Clinical data interpretation

Executive presence

Matrix leadership

Regulatory affairs

Communication

Education

Medical degree

Residency or specialty training

Job description

GlaxoSmithKline is seeking a medical safety leader in oncology to guide pharmacovigilance strategies across clinical development. You will analyze safety signals, engage with governance, and provide evidence-based recommendations to protect patient safety while shaping the safety profile of oncology medicines.

The role requires a medical degree with strong clinical judgment, extensive experience in pharmacovigilance, and the ability to lead cross‑functional teams in a global matrix environment.