Senior Vice President, Technical Operations

Invivyd, Inc.; New Haven (CT); On-site; USD 304,000 - 425,000; Full time

Job summary

Invivyd, Inc. is seeking a Senior Vice President, Technical Operations to lead our Technical Operations group. This role shapes strategy, directs execution across CMC development, manufacturing, supply chain, and quality control, and partners with CDMOs and regulatory authorities.

The SVP will drive cross-functional collaboration, provide leadership to a top-tier team, and ensure alignment with corporate objectives in a fast-growing biotech environment. Hybrid in-office schedule required.

Qualifications

• PhD or equivalent in biologics-focused field with development/manufacturing experience.
• 15+ years in pharmaceutical/biotech, startup exposure a plus.
• Proven leadership of a cross-functional team and budget ownership.
• Experience with biologics CMC, analytical/formulation development.
• CDMO selection/oversight and knowledge of cGMPs required.

Responsibilities

• Oversee Technical Operations including manufacturing, supply chain, and QC.
• Develop and execute manufacturing strategy for clinical and commercial products.
• Direct CMC development activities across process, analytics, and formulation.
• Provide operations oversight to strategic decisions and cross-functional plans.
• Lead interactions with CDMOs and external service providers.
• Coordinate with Regulatory Affairs to craft CMC strategies.
• Represent Invivyd to regulators and industry partners.
• Build strong cross-department relationships for transparency.
• Plan for cross-functional transitions within the team.

Skills

Leadership

Strategic thinking

Biologics development

CMC development

Regulatory affairs

Vendor management

Education

PhD in Biochemical Engineering / Biochemistry or equivalent with biologics

Tools

CDMOs management

Job description

Senior Vice President, Technical Operations

ABOUT US

There are more than 9 million immunocompromised people in the United States. Almost half a million of those represent a population that are moderately to severely immunocompromised and at highest risk for severe COVID-19, including stem cell and solid organ transplant patients as well as those with hematologic cancers.

At Invivyd, Inc., we take those numbers very seriously and we come to work each day on a mission to deliver protection from serious viral infectious diseases, beginning with SARS-CoV-2. Invivyd deploys a proprietary integrated technology platform unique in the industry designed to assess, monitor, develop, and adapt to create best in class antibodies.

In March 2024, Invivyd received emergency use authorization (EUA) from the U.S. FDA for a monoclonal antibody (mAb) in its pipeline of innovative antibody candidates.

In October 2025, the FDA cleared the company's Investigational New Drug (IND) application and provided feedback to advance the company's REVOLUTION clinical program, Invivyd's development program for VYD2311, a vaccine alternative monoclonal antibody being investigated for the prevention of COVID-19.

Be part of making a difference. Be part of Invivyd.

Job Title: Senior Vice President, Technical Operations

Location: This will be a hybrid role, with a weekly in-office requirement of at least 3 days (Monday, Tuesday, Wednesday)

Position summary:
The Senior Vice President, Technical Operations will provide leadership and direction for Invivyd’s Technical Operations group. The SVP is responsible for strategy, direction, and execution of technical initiatives in partnership across the organization and provides oversight to the entire Technical Operationsteam.

Responsibilities:

• Oversee the Technical Operations group including CMC Development, Manufacturing (drug substance, drug product), Supply Chain and Distribution, and Quality Control.
• Develop and execute Invivyd’s overall clinical and commercial manufacturing strategy including planning, contracting, CDMO oversight, and execution including supply and distribution.
• Direct CMC development activities including process, analytical and formulation activities for Invivyd’s clinical and commercial product candidates.
• Provide technical operations oversight to strategic decision making
• Lead interactions with CDMOs and other contract services needed to execute the Technical Operations plan and strategy.
• Provide support and work with other functional areas to develop and communicate the overall corporate strategy.
• In close coordination with Regulatory Affairs, develop and communicate CMC regulatory strategies to fit the company’s objectives.
• Represent Invivyd to external audiences, including regulatory authorities and biotechnology industry collaborators/partners.
• Build strong working relationships across departments to ensure transparency and to facilitate communication.
• Lead the team through planning for cross-functional transitions.

Qualifications:

• PhD or equivalent in Biochemical Engineering, Biochemistry or equivalent with biologics (including antibody)-based development and manufacturing experience.
• 15 years minimum experience in pharmaceutical and/or biotechnology industry, start-up experience a plus.
• Multiple years of management experience leading a collaborative team.
• Proven success record in overseeing a department, including staffing and budget activities.
• Experience with biologics development including process, analytical, and formulation development activities.
• Experience with both early and late clinical stage CMC development required, including validation and commercialization experience.
• Experience with CDMOs including selection and management; knowledge of cGMPs essential.
• Experience in a development organization including integration with research, non-clinical, and clinical groups is desirable.
• CMC regulatory experience essential, including IND / IMPD filings and BLA submissions.
• Must have excellent leadership and interpersonal skills; should have proven skills as an effective team player who can engender credibility and confidence within and outside the company.
• Must be science- and data-driven

Pay Range

$304,000- $425,000The pay range represents the expected full-time base salary for this role at the time of posting. Actual base pay will be determined based on a variety of factors, including relevant experience, skills, and education. In addition to base pay, this role is eligible for both an annual short-term incentive (e.g., bonus or sales incentive) and an annual long-term incentive (e.g., equity), reflecting our commitment to rewarding strong performance and long-term impact. Learn more about our total rewards by visiting https://www.invivyd.com/careers/ .

At Invivyd we strive to create a welcoming and inclusive environment. Here all applicants will receive equal consideration for employment without discrimination on the basis of race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability, or any other applicable legally protected characteristics.

Invivyd is proud to be an equal opportunity employer.