Senior Upstream Equipment Engineer for Lifecycle & Reliability

BioSpace; Framingham (MA); On-site; USD 120,000 - 150,000; Full time

Benefits offered by this job

No-listed perks

Job summary

Sanofi US Services in Framingham, MA is seeking a Senior Equipment Process Engineer-Upstream to own an asset portfolio, improve safety, reliability, and lifecycle performance.

You will lead maintenance plans, troubleshoot complex issues, and coordinate with Operations, Quality, and Automation to deliver compliant, cost-effective results.

This role combines hands-on work with rigorous documentation and cross-functional leadership in a regulated biopharma environment.

Qualifications

• Bachelor's degree in mechanical, electrical, chemical, biomedical, or related engineering discipline.
• 3+ years engineering experience supporting manufacturing, facilities, utilities, laboratories, or complex process equipment in a regulated or high-reliability environment.
• Demonstrated equipment troubleshooting capability using drawings, manuals, data, failure history, and structured root-cause methods.
• Experience developing job plans, PM tasks, technical specifications, spare-parts recommendations, or maintenance strategies.
• Experience supporting equipment modifications, commissioning, qualification, change control, deviations, or CAPAs.
• Ability to work effectively in the field and communicate technical risk and recommendations to technical teams and leaders.

Responsibilities

• Own equipment performance and lifecycle: Maintain asset health, design basis, operating limits, criticality, failure history, documentation, maintenance strategy, obsolescence risks, and improvement priorities.
• Lead troubleshooting and field support: Diagnose mechanical, electrical, instrumentation, and control-interface issues; collaborate with mechanics and technicians.
• Build executable maintenance plans: Develop work packages with scope, sequence, labor, parts, tools, permits, LOTO, acceptance criteria, tests, turnover.
• Optimize preventive maintenance and spares: Create risk-based PM strategies, BOMs, critical-spares lists, stocking recommendations, obsolescence plans.
• Lead equipment changes and projects: Define technical requirements, lead design reviews, vendor selection, FAT/SAT, commissioning, turnover, training.
• Own technical quality actions: Lead change controls and CAPAs, assess deviations, ensure hardware changes are implemented and closed.
• Drive reliability improvement: Use downtime and deviations to reduce failures and improve maintainability, safety, and compliance.
• Coordinate vendors and stakeholders: Develop scopes, assess vendor capability, collaborate with Operations, Quality, Validation, Metrology, HSE, Automation, Engineering, Procurement, Stores, and Finance.

Skills

Troubleshooting

Maintenance planning

Field support

Cross-functional leadership

Documentation

Education

Bachelor's degree in engineering

Tools

CMMS/EAM

P&IDs & drawings

OEM technical packages

Job description

Sanofi US Services in Framingham, MA is seeking a Senior Equipment Process Engineer-Upstream to own an asset portfolio, improve safety, reliability, and lifecycle performance.

You will lead maintenance plans, troubleshoot complex issues, and coordinate with Operations, Quality, and Automation to deliver compliant, cost-effective results.

This role combines hands-on work with rigorous documentation and cross-functional leadership in a regulated biopharma environment.