Senior Systems Engineer

Capricor; San Diego (CA); On-site; USD 100,000 - 130,000; Full time

Job summary

Capricor in San Diego is seeking a Senior Systems Engineer to design, implement, and support enterprise IT infrastructure in a fast-paced biotech environment. This role focuses on maintaining secure, scalable systems across cloud and on-prem environments.

The ideal candidate will have 6+ years of experience, strong expertise in Windows and Linux systems, cloud platforms, and automation skills. Join Capricor to contribute to innovative cell and exosome-based therapies that make a real difference.

Qualifications

• 6+ years of experience in systems engineering or infrastructure roles.
• Strong expertise in Windows Server, Linux systems, and cloud platforms.
• Experience in biotechnology or regulated environments preferred.

Responsibilities

• Design and maintain enterprise IT infrastructure.
• Implement and secure cloud and on-prem environments.
• Lead infrastructure upgrades and lifecycle management.

Skills

Windows Server & Active Directory

Linux systems administration

Virtualization (VMware, Hyper-V)

Cloud platforms (AWS and/or Azure)

Backup solutions (VEEAM)

Scripting/automation (PowerShell)

Troubleshooting and root cause analysis

Education

Bachelor’s degree in IT, Computer Science, or related field

Tools

Microsoft Intune

SolarWinds

Palo Alto Networks

Veeam backup solution

Job description

Capricor Therapeutics (NASDAQ: CAPR) is a biotechnology company dedicated to advancing transformative cell and exosome-based therapies for rare diseases. At the forefront of our innovation is Deramiocel (CAP-1002), our lead cell therapy in late-stage development for Duchenne muscular dystrophy. We are also harnessing our proprietary StealthX™ exosome platform to unlock new possibilities in targeted delivery and vaccinology. Every program reflects our commitment to pushing the boundaries of science and delivering life‑changing treatments to patients and families who need them most.

We are seeking a highly skilled and hands‑on Senior Systems Engineer to design, implement, and support enterprise IT infrastructure in a fast‑paced biotech environment. This role will be responsible for maintaining highly available, secure, and scalable systems across cloud and on‑prem environments.

The ideal candidate brings deep expertise in systems engineering, cloud platforms, automation, and security, with experience operating in regulated environments (GMP, SOX, etc.).

Systems Engineering & Infrastructure

• Design, implement, and maintain enterprise infrastructure (Windows/Linux servers, virtualization, storage)
• Manage hybrid environments spanning on-prem and cloud (AWS/Azure)
• Ensure high availability, performance, and scalability of systems
• Lead infrastructure upgrades, patching, and lifecycle management

Cloud & Modernization

• Architect and support cloud infrastructure in AWS and/or Azure
• Lead cloud migrations and optimization initiatives
• Optimize cost, performance, and reliability of cloud resources

Security & Compliance

• Implement and maintain system security best practices
• Partner with security teams on vulnerability management and remediation
• Ensure compliance with GMP, SOX, and FDA requirements
• Manage identity and access controls (SSO, MFA, RBAC)

Monitoring, Automation & Performance

• Implement and maintain monitoring and alerting solutions
• Automate repetitive tasks using scripting (PowerShell)
• Perform root cause analysis and performance tuning
• Maintain system documentation

Collaboration & Escalation Support

• Act as Tier 3 escalation point for complex infrastructure issues
• Partner with Help Desk, Network, and Security teams
• Support IT projects and cross‑functional initiatives
• Provide technical mentorship to junior engineers

Qualifications

• Bachelor’s degree in IT, Computer Science, or related field (or equivalent experience)
• 6+ years of experience in systems engineering or infrastructure roles
• Strong expertise in: Windows Server & Active Directory, Linux systems administration, Virtualization (VMware, Hyper‑V), Cloud platforms (AWS and/or Azure), Backup solutions (VEEAM)
• Experience with scripting/automation (PowerShell)
• Experience with backup, disaster recovery, and high availability design
• Experience in biotech, pharma, or regulated environments
• Knowledge of GMP, HIPAA, SOX, or FDA compliance frameworks
• Certifications such as: Microsoft (Azure Administrator/Architect), AWS Solutions Architect, and VMware (VCP)
• Experience with enterprise tools such as: Microsoft Intune, SolarWinds, Palo Alto Networks, and Veeam backup solution
• Strong troubleshooting and root cause analysis skills
• Ability to work independently and manage complex systems
• Excellent documentation and organizational skillsStrong communication with both technical and non‑technical stakeholders
• Proactive, automation‑first mindset

Why Capricor?

Capricor Therapeutics is advancing cell and exosome‑based therapies with a focus on serious diseases where patients and families need new treatment options. Our work is grounded in scientific rigor, collaboration, and a shared commitment to moving meaningful therapies forward. Joining Capricor means being part of a mission‑driven team working at the intersection of innovation, execution, and patient impact.

Come Work With Us

At Capricor, you’ll join a collaborative environment where employees are encouraged to contribute, grow, and help build the systems, science, and operations needed to support our next stage of growth. We value people who are thoughtful, accountable, hands‑on, and motivated by work that can make a real difference.