Senior Statistician

F. Hoffmann-La Roche AG; South San Francisco (CA); On-site; USD 136,900 - 254,200; Full time

Job summary

F. Hoffmann-La Roche AG seeks a Senior Statistician in South San Francisco to apply statistical expertise in clinical trials. You'll develop protocols, conduct analyses, and collaborate with teams to ensure scientific rigor.

Qualifications include an MSc or PhD in Statistics with at least 3 years in pharma or biotech. The role offers an expected salary range of $136,900 – $254,200, plus potential annual bonuses based on performance.

Qualifications

• Minimum 3 years of experience in clinical trial statistics in pharma or biotech.
• Demonstrated experience in design, analysis, and interpretation of clinical trials.
• Solid understanding of regulatory expectations for clinical development.

Responsibilities

• Contribute to protocol development and statistical analysis plans.
• Perform or oversee data analyses while resolving analytical challenges.
• Collaborate with cross-functional teams to align deliverables.

Skills

SAS

R

Statistical analysis

Problem-solving

Critical thinking

Education

MSc, PhD, or equivalent in Statistics or Biostatistics

Tools

CDISC standards

Job description

About the role

The Senior Statistician is a key member of a cross‑functional study or molecule team. The role applies statistical expertise to design, conduct, analyze, and interpret individual clinical trials, ensuring scientific rigor and regulatory compliance.

Responsibilities

• Contribute to protocol development and author statistical analysis plans.
• Perform or oversee data analyses and resolve analytical challenges.
• Represent Biostatistics and PDD at study team levels, ensuring statistical rigor.
• Collaborate proactively with cross‑functional teams to align deliverables and timelines.
• Interpret and communicate results in context, influencing study‑level decisions.
• Lead statistical contributions to CSRs and selected regulatory documents.
• Provide functional guidance and informal mentoring to less experienced statisticians.
• Lead or influence study‑level projects or contribute to large project teams or initiatives.

Qualifications

• Hold an MSc, PhD, or equivalent in Statistics, Biostatistics, or a closely related quantitative field.
• Minimum 3 years of experience in clinical trial statistics in pharma, biotech, or CRO settings.
• Demonstrated experience in design, analysis, and interpretation across different phases.
• Solid understanding of regulatory expectations and statistical methodologies for clinical development.
• Proficiency in SAS and/or R, and familiarity with CDISC standards.
• Ability to work autonomously while collaborating effectively in cross‑functional teams.
• Strong problem‑solving, critical thinking, and strategic agility.
• Excellent verbal and written communication skills, especially in presentation and scientific writing.
• Respect for cultural differences and ability to work in a global workplace.
• Preferable: experience in CVRM diseases, cross‑functional global study teams, translating complex concepts for non‑statistical audiences, early/late drug development, mentoring or scientific leadership in a matrix organization, and strategic portfolio decisions.

Location & Compensation

The position is based in South San Francisco or Boston. Relocation benefits are not available for this posting. Expected salary range for primary location of California is $136,900 – $254,200. Actual pay will be determined based on experience, qualifications, geographic location, and other job‑related factors permitted by law. A discretionary annual bonus may be available based on individual and company performance.

Equal Opportunity Employer

Genentech is an equal‑opportunity employer. The company prohibits unlawful discrimination, including on the basis of protected veteran status, disability status, and consistent with all federal, state, or local laws. If you have a disability and need an accommodation, please contact us by completing this form Accommodations for Applicants.