Senior / Staff Machine Learning Engineer, Applied AI

Lila Sciences, Inc.; Cambridge (MA); On-site; USD 180,000 - 298,000; Full time

Benefits offered by this job

Comprehensive benefits

Equity

Relocation support

Job summary

Lila Sciences is seeking a Senior / Staff Machine Learning Engineer, Applied AI to drive model post-training, evaluation, and production-ready ML systems. You will shape how Lila’s AI models are adapted to customer scientific needs, turning frontier capabilities into reliable workflows used in real customer contexts.

You will collaborate with AI researchers and software teams to translate advances into usable capabilities, run post-training work (SFT, RL methods), build evaluation loops, and

Qualifications

• Experience with post-training methods (SFT, RL) and evaluation design.
• Strong Python and PyTorch proficiency.
• Ability to debug complex model behavior with data and traces.
• Familiarity with large language and multi-modal models.
• Clear written and verbal communication across technical and non-technical audiences.

Responsibilities

• Close the last-mile gap between model capabilities and scientific workflows.
• Run post-training work (SFT, RL) to align models with customer requirements.
• Design and run evaluation loops to measure quality, reliability, and customer fit.
• Translate customer learnings and evaluation results into concrete model improvements.
• Collaborate with AI researchers to translate model advances into usable capabilities.
• Work with software teams to integrate model behavior into end-to-end product workflows.
• Debug complex model failures using traces, evaluations, and customer context.

Skills

Python

PyTorch

Post-training ML

Evaluation systems

LLMs / multi-modal AI

Debugging/model behavior

Communication skills

Tools

Tracing & logs analysis

Model deployment

Job description

Your Impact at LILA

We are growing our Applied AI org and seeking a Senior / Staff Machine Learning Engineer, Applied AI with expertise in model post-training, evaluation, and production-oriented ML systems. You’ll shape how Lila’s AI models are adapted to customer‑specific scientific needs, with a focus on turning frontier model capabilities into reliable workflows that can be evaluated, iterated and used in real customer contexts.

Applied AI sits at the intersection of AI Research, model engineering, and product deployment. The team partners closely with AI Researchers and Software teams to adapt Lila models to customer workflows, improve model quality through post training and driving how harness engineering shapes model behavior inside the product.

This is the right role for someone who wants to go deep on model adaptation and evaluation, take real ownership of hard technical problems, and grow into broader scope over time.

What You'll Be Building

• Apply hands‑on expertise to close the last‑mile gap between Lila's model capabilities and customer‑specific scientific workflows.
• Run post-training work using approaches such as SFT and RL (DPO, PPO/GRPO) to align model behavior with customer-specific requirements and feedback.
• Run evaluation loops that measure model quality, reliability, and customer fit.
• Turn customer learnings, data signals, and evaluation results into concrete model improvement cycles.
• Partner with AI researchers to translate model advances into reliable, usable capabilities.
• Work with Software to integrate model behavior into end‑to‑end product workflows.
• Debug complex model failures using traces, evaluations, customer context, and scientific feedback.

What You'll Need To Succeed

• Minimum 1-2 years of hands‑on post‑training experience (SFT, RL methods such as DPO/PPO/GRPO) and evaluation system design, gained from having solved these problems many times before.
• Strong software engineering skills in Python and modern ML frameworks like PyTorch.
• A demonstrated ability to debug ambiguous, high‑stakes model behavior quickly, using data, traces, logs, and qualitative feedback - the kind of judgment that only comes from having seen many failure modes before.
• Deep familiarity with large language models, multi‑modal models, or agentic AI systems.
• Clear communication skills for translating customer needs into technical approaches, and for explaining complex model behavior to both technical and non‑technical audiences.

Bonus Points For

• Experience adapting models for customer‑facing or production workflows, ideally in scientific, technical, or data‑intensive domains.
• Experience with RL post‑training, such as RLHF, GRPO, or tool‑augmented RL.
• Experience building evaluation harnesses, model monitoring, or quality dashboards.
• Experience training MoE architectures.
• A track record of mentoring engineers and being sought out as a go‑to technical expert, rather than a people manager or strategy owner.

Compensation

CompensationWe offer competitive base compensation with bonus potential and generous early‑stage equity. Your final offer will reflect your background, expertise, and expected impact.

U.S. Benefits. Full‑time U.S. employees receive a comprehensive benefits program including medical, dental, and vision coverage; employer‑paid life and disability insurance; flexible time off with generous company wide holidays; paid parental leave; an educational assistance program; commuter benefits, including bike share memberships for office based employees; and a company subsidized lunch program.

International Benefits. Full‑time employees outside the U.S. receive a comprehensive benefits program tailored to their region. USD salary ranges apply only to U.S.-based positions; international salaries are set to local market.

Expected Base Salary Range: $180,000 USD - $298,000 USD

About LILA

Lila Sciences is building Scientific Superintelligence™ to solve humankind's greatest challenges. We believe science is the most inspiring frontier for AI. Rather than hard‑coding expert knowledge into tools, LILA builds systems that can learn for themselves.

LILA combines advanced AI models with proprietary AI Science Factory™ instruments into an operating system for science that executes the entire scientific method autonomously, accelerating discovery at unprecedented speed, scale, and impact across medicine, materials, and energy. Learn more at www.lila.ai.

Guided by our core values of truth, trust, curiosity, grit, and velocity, we move with startup speed while tackling problems of historic importance.

We’re All In

Lila Sciences is committed to equal employment opportunity regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity or Veteran status.

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