Senior Security Architect: Cyber Ops & IR

City of Hope; United States; On-site; USD 140,000 - 180,000; Full time

Job summary

City of Hope is seeking a Principal Security Architect to lead enterprise detection, monitoring, and incident response programs across clinical, research, and technology environments. The role defines security architecture, standards, and capabilities for SIEM, SOAR, UEBA, threat intelligence, and cyber defense.

You will collaborate with SOC and cross-functional teams to ensure actionable telemetry, rapid investigations, and measurable risk reduction, while guiding governance, risk, and

Qualifications

• Bachelor’s degree in Computer Science, Cybersecurity, Information Security, MIS or related field.
• Nine+ years of cybersecurity experience with depth in security architecture or security engineering.
• Experience designing security controls across complex multi-vendor environments.
• Preferred Master’s degree in cybersecurity or related technology field.
• Certifications such as CISSP, GCIH, GCFA, GCIA, GMON, GNFA, GCFE, GRID, SC-200 or equivalent.

Responsibilities

• Define and maintain enterprise architecture, standards, and roadmaps for SOC operations, SIEM, SOAR, UEBA, threat intelligence, digital forensics, incident response, and cyber defense platforms.
• Lead design and optimization of enterprise detection engineering programs, security monitoring capabilities, threat hunting frameworks, use-case development, and adversary detection strategies aligned with MITRE ATT&CK and industry best practices.
• Architect and enhance incident response, forensic investigation, cyber resilience, ransomware recovery, and crisis management capabilities across enterprise environments.
• Lead assessment and improvement of security telemetry, log management, detection coverage, alert fidelity, incident workflows, automation opportunities, and response processes.
• Partner with security engineering teams to ensure security technologies generate adequate logging, visibility, and actionable telemetry to support detection and response objectives.
• Provide strategic leadership and technical guidance to SOC analysts, incident responders, threat hunters, detection engineers, and management teams. Develop documentation, standards, executive metrics, and board-level reporting.
• Evaluate emerging threats, adversary techniques, AI-assisted attack methods, security operations technologies, and threat intelligence capabilities to enhance organizational cyber defense effectiveness.
• Follows established City of Hope and department policies, procedures, objectives, performance improvement, attendance, safety, environmental, and infection control guidelines, including adherence to the workplace code of Conduct and Compliance Plan.
• Practices a high level of integrity and honesty in maintaining confidentiality.
• Performs other related duties as assigned or requested.

Skills

SOC leadership

Incident response

Detection engineering

Threat intelligence

MITRE ATT&CK

Threat hunting

Automation opportunities

Log management

Security telemetry

Education

Bachelor’s degree in Computer Science or related field

Master’s degree in Cybersecurity or related field

Tools

CISSP

GCIH

GCFA

GCIA

GMON

GNFA

GCFE

GRID

SC-200

Job description

City of Hope is seeking a Principal Security Architect to lead enterprise detection, monitoring, and incident response programs across clinical, research, and technology environments. The role defines security architecture, standards, and capabilities for SIEM, SOAR, UEBA, threat intelligence, and cyber defense.

You will collaborate with SOC and cross-functional teams to ensure actionable telemetry, rapid investigations, and measurable risk reduction, while guiding governance, risk, and