Senior Scientist, Translational Research

Triveni Bio; Watertown (MA); On-site; USD 120,000 - 180,000; Full time

Benefits offered by this job

Equity

Bonus potential

Comprehensive benefits

Job summary

Triveni Bio is seeking a motivated Scientist to lead image‑based biomarker analyses and drive experimental design for cell‑based and ex vivo preclinical models. You will shape the biomarker strategy across indications, advancing therapeutics targeting novel pathways.

The role requires a Ph.D. with 5+ years in biotech/pharma, strong HALO experience, and a track record in immunology/inflammation research, including collaboration with CROs and academics.

Qualifications

• PhD with 5+ years in pharma/biotech and hands-on HALO imaging.
• Strong background in Immunology and Inflammation, especially skin-related pathways.
• Experience designing mechanistic cell-based and ex vivo assays.
• Proven track record coordinating CROs, vendors, and academics.

Responsibilities

• Lead image-based biomarker analyses using HALO to support biomarker work.
• Design and execute cell-based and ex vivo preclinical models.
• Oversee external research activities with CROs and collaborators to meet timelines.

Skills

HALO image analysis

Immunology & inflammation

Cell-based & ex vivo assays

CRO/vendor management

Education

Ph.D. in molecular biology or related field

Job description

Company Introduction

Triveni Bio is breaking new ground in the identification of novel disease targets – working at the convergence of human genetics, best‑in‑class antibody design, and precision medicine. We are pioneering a Mendelian genetics‑informed precision medicine approach to develop functional antibodies for the treatment of immunological and inflammatory disorders. Our lead antibody program (TRIV‑509) targets kallikreins 5 and 7 (KLK5/7) to directly impact skin barrier function, inflammation, and itch – providing a meaningful and much needed potential treatment option for patients with atopic dermatitis and other barrier disorders. In all the work we do, we adhere to our core values: patient impact, bold and rigorous science, open collaboration, kindness & respect.

Summary

Triveni Bio is seeking a highly motivated and experienced Scientist to join our Biology and Translational Research team. In this role, you will lead image‑based biomarker analyses and drive the experimental design and execution of cell‑based and ex vivo preclinical models. This is an exciting opportunity to shape the scientific biomarker strategy across multiple indications, advancing therapeutics that target novel disease pathways. If you are passionate about therapeutic discovery and possess extensive expertise in image analysis, we want to hear from you.

Responsibilities

• Lead image‑based biomarker analyses using HALO to support biomarker analyses
• Design and execute experimental cell‑based and ex vivo preclinical models
• Oversee external research activities to meet timelines, deliverables, and data quality with Contract Research Organizations (CROs) or academic collaborators

Experience & Qualifications

• Ph.D. in molecular biology or a related discipline with 5+ years of experience within the pharmaceutical or biotechnology sectors
• Extensive, hands‑on expertise in image analysis utilizing HALO
• Solid background in Immunology and Inflammation indications, with a strong preference for specific experience in atopic dermatitis
• Familiarity or expertise in mechanistic cell‑based and cell‑free assays to investigate type 2 immunity, including immune cells, mast cells, IgE biology, cytokine modulation, and other relevant pharmacodynamic readouts
• Proven track record of effectively managing Contract Research Organizations (CROs), external vendors, and academic collaborators

Compensation and Benefits

The posted range reflects the current reasonable and good faith estimate of the base salary for this full‑time position. Actual compensation will be based on a variety of factors including, but not limited to, relevant skills and experience, educational background and certifications, performance and qualifications, market demand for the role, geographic location and other organizational needs. This role also offers a competitive target bonus, equity, and a comprehensive benefits package.

We are committed to fair pay practices, and we regularly review our compensation programs to ensure they are competitive, equitable, and aligned with our values. Please note that the advertised pay range is not a guarantee or promise of a specific wage.