Senior Scientist, Translational Development

Biopharma Careers; Virginia (MN); On-site; USD 142,000 - 172,000; Full time

Benefits offered by this job

Wellbeing support

Flexible Time Off

11 holidays per year

Stock opportunities

Job summary

Bristol Myers Squibb is seeking a Senior Scientist in Translational Development to lead the preclinical/commercial bench work for immune-oncology programs in Cambridge, MA. You will drive mechanism-of-action studies, differentiate from standard therapies, and address resistance mechanisms with cross-functional teams.

The role requires a PhD with relevant post-graduate experience, an outstanding publication record, and the ability to manage multiple programs while delivering high-quality

Qualifications

• PhD with at least 2 years of relevant work experience in immune-oncology, hematology or immunology.
• Excellent publication record in high-tier scientific journals and a strong research track record.
• Demonstrated ability to lead innovative laboratory efforts to support clinical development.

Responsibilities

• Lead preclinical/laboratory studies to support translational strategies and programs.
• Deliver data on biomarkers, dose/schedule, and resistance mechanisms to inform development.
• Collaborate with internal and external researchers to ensure seamless information flow.
• Contribute to external preclinical collaborations within the asset pipeline.
• Maintain written reports and present results in an organized, timely manner.
• Communicate effectively and contribute to project strategy discussions.

Skills

Scientific communication

Team leadership

Collaboration

Project management

Education

PhD in Immunology/Oncology/related field

Tools

Flow cytometry

Cell sorting

ELISA/MSD

RNA-seq (bulk)

Spatial transcriptomics

Job description

At Bristol Myers Squibb, our employees often ask, “Who are you working for?”, a question that fuels collaboration, accountability, and urgency in our work. Our purpose-driven culture inspires us to discover, develop, and deliver innovative medicines to prevail over serious diseases. We offer uniquely interesting and meaningful work, opportunities for growth, and a supportive environment that values inclusion, wellbeing, flexibility, and comprehensive benefits. This is work that transforms the lives of patients, and the careers of those who do it.

Translational Development at BMS

Translational Development is part of the Global Research organization in BMS and leads late-stage clinical, pharmacological and translational research and development activities for the pipeline and supports late-stage portfolio for regulatory, translational development and life cycle management. Translational Development drives strategy across core therapeutic areas at BMS including hematology, oncology, immunology, cardiovascular and neuroscience. This group integrates laboratory science, clinical trial/biomarkers and asset development as well as disease research to maximize the potential of BMS current and future therapeutics.

Position Summary

Reporting to Director/Translational Development, the new role will be part of the translational group based in Cambridge, MA and will manage the scientific and preclinical laboratory component of multiple immune-oncology interfacing late-stage programs (phase 2 and beyond). Key responsibilities of this role are to lead from the bench supporting programs through mechanism of action-based studies, differentiation from standard of care molecules, combination rationale and resistance mechanisms.

Key Responsibilities

• Performs preclinical/laboratory studies involving late-stage BMS assets to support annual goals and objectives for the Translational Medicine research group
• Responsible for delivering data in support of translational strategies including biomarkers, patient selection hypotheses, dose and schedule, combination strategies, resistance mechanisms and differentiation
• Interfaces with other research scientists within and outside of Translational Medicine to ensure seamless flow of information
• May contribute to external preclinical collaborations across the clinical asset pipeline
• Accurately maintain written reports and present results in an organized and timely manner
• Communicate effectively, foster teamwork and contribute to project strategy discussions

Qualifications & Experience

• PhD with at least 2 years of relevant work experience in an academic or industry setting focusing on immune-oncology, hematology and/or immunology
• Excellent publication record in high tier scientific journals and strong research track record in academic or industry setting, leading innovative efforts within the laboratory to achieve defined goals and support clinical development

Technical Skills

• In vitro: Multi-parameter flow cytometry and cell sorting in the context of primary immune cell characterization, cellular based immune effector assays (ADCC, ADCP, T-cell killing), cytokine analysis (ELISA/MSD), bulk/sc-RNA-seq.
• In vivo: end-to-end syngeneic and CDX-based efficacy studies (i.v./p.o.), tumor immunophenotyping and transcriptomic profiling
• Experience with spatial technology platforms (e.g. Akoya, Visium, COSMX or similar) a plus.
• Ability to work with disease teams/experts to develop preclinical strategies to support clinical development and life cycle management
• Strong verbal and written communication skills with experience in developing written documents such as primary manuscripts/publications are essential
• Strong commitment to quality, integrity, accountability and demonstrated adaptability
• Excellent communication, managerial and scientific qualities are expected
• High competency in scientific analysis, innovative solutions and the ability to strategically prioritize goals.

Compensation Overview

Cambridge Crossing: $142,220 - $172,340

The starting pay range(s) listed above is for full-time employees (FTE). You may also be eligible for additional discretionary incentive cash and stock opportunities. We determine starting pay thoughtfully – carefully considering the nature of the role, required skills, work location, schedule and the knowledge and experience you bring. Final compensation is guided by pay equity principles and applicable employment laws. Compensation programs are reviewed on an ongoing basis and may be adjusted over time to reflect evolving market factors, and individual, team or Company performance.

Benefits

Subject to the terms and conditions of the applicable plans then in effect, you may be eligible to participate in our comprehensive benefit plans – including wellbeing support, retirement and financial protection benefits, and insurance offerings (medical, dental, vision, life and disability).

U.S.-based exempt employees are eligible for Flexible Time Off (FTO), which provides paid time off without a set accrual limit, subject to manager approval, along with 11 paid company holidays each year.

Non-exempt employees, RayzeBio employees, and employees located in Puerto Rico receive 160 hours of paid vacation annually for new hires (subject to manager approval), 11 paid company holidays, and 3 optional holidays.

Depending on eligibility, employees may also have access to additional time-off benefits, including paid sick leave, up to two paid volunteer days per year, summer hours flexibility, and leaves of absence for medical, personal, parental, caregiver, bereavement, or military needs. Eligible employees also enjoy an annual Global Shutdown between Christmas Day and New Year's Day.

U.S.-based job seekers can explore full benefit offerings at https://careers.bms.com/benefits

How We Work

Where you work matters – because collaboration, innovation and patient impact happen in many settings. Our roles are structured across four work models: site-essential, site-by-design, field-based and remote-by-design. The model assigned to this role is based on its core responsibilities. Learn more at https://careers.bms.com/ways-of-working.

Supporting People with Disabilities

BMS is dedicated to ensuring that people with disabilities can excel through a transparent recruitment process, reasonable workplaceaccommodations/adjustmentsand ongoing support in their roles. Applicants can request a reasonable workplaceaccommodations/adjustmentsprior to accepting a job offer. If you require reasonableaccommodations/adjustmentsin completing this application, or in any part of the recruitment process, direct your inquiries to [e-mail] . Visit careers.bms.com/eeo-accessibility to access our complete Equal Employment Opportunity statement.

Candidate Rights

BMS will consider qualified applicants with arrest and conviction records, pursuant to applicable laws in your area.

For roles based in Los Angeles County only: If you live in or expect to work from Los Angeles County if hired for this position, please visit this page for important additional information: https://careers.bms.com/california-residents/

Data Protection

We will never request payments, financial information, or social security numbers during our application or recruitment process. Learn more about protecting yourself at https://careers.bms.com/fraud-protection .

Any data processed in connection with role applications will be treated in accordance with applicable data privacy policies and regulations.

If this posting is missing required information required by local law or incorrect, contact BMS at [e-mail] with the Job Title and Requisition number. Do not send application-related inquiries to this email. To check your application status, please login to your Candidate Home Account.

R1605777 : Senior Scientist, Translational Development