Senior Scientist, Systems Biology

BioSpace; Cambridge (MA); On-site; USD 130,000 - 170,000; Full time

Job summary

Sanofi is seeking a Senior Scientist, Systems Biology in Cambridge, MA to decode disease mechanisms at cellular resolution and develop AI-powered workflows accelerating discovery to patient impact. Join the Systems and Disease Biology Cluster to advance innovative therapeutics.

The role emphasizes analysis of spatial and single-cell multiomic data, design of agentic workflows, collaboration across teams, mentoring interns, and dissemination through publications and presentations.

Qualifications

• PhD by Aug 2026 in systems biology, computational biology, computer science, applied mathematics, or a related field.
• Experience in analyzing cellular multiomic data using Python.
• Hands-on experience building or deploying agentic analysis workflows.

Responsibilities

• Analyze and leverage spatial and single-cell multiomic data to delineate pathogenic cell states and tissue microenvironments.
• Design intelligent agentic workflows that streamline deployment of innovative algorithms and computational models.
• Contribute to evaluation and application of foundation models and virtual cell models.
• Collaborate with biologists, chemists, data scientists, and other stakeholders.
• Lead and contribute to high-profile presentations and publications, communicating research findings.
• Mentor interns and junior scientists to foster a collaborative research environment.

Skills

Agentic workflows

Education

PhD completed by Aug 2026

Tools

Python

Job description

Job Title: Senior Scientist, Systems Biology

Location: Cambridge, MA

About The Job

As a Senior Scientist in Systems Biology within our Systems and Disease Biology Cluster, you will decode disease mechanisms at cellular resolution and pioneer AI-powered workflows that accelerate the path from discovery to patient impact. Ready to get started?

The Systems and Disease Biology Cluster, part of the Target, Disease, and Systems Biology function at Sanofi Research, is dedicated to delivering first-in-class medicines to patients. Our approach involves deconstructing disease mechanisms into cellular building blocks and advancing innovative therapeutics for the precise targeting of pathogenic cell types.

We are in search of a highly skilled, independent, proactive, and well-organized Senior Scientist. The ideal candidate will possess expertise in complex cellular analytics, as well as strong data science skills to help build upon our current achievements and secure our future success. Experience in developing and deploying modern agentic analysis workflows to accelerate discovery timelines and create reusable analytical templates is highly valued.

Join the engine of Sanofis mission where deep immunoscience meets bold, AI-powered research. In R&D, youll drive breakthroughs that could turn the impossible into possible for millions.

About Sanofi

We’re an R&D-driven, AI-powered biopharma company committed to improving peoples lives and delivering compelling growth. Our deep understanding of the immune system and innovative pipeline enables us to invent medicines and vaccines that treat and protect millions of people around the world. Together, we chase the miracles of science to improve peoples lives.

Main Responsibilities

• Analyze and leverage spatial and single-cell multiomic data to delineate pathogenic cell states and tissue microenvironments, generating actionable mechanistic insights and novel target hypotheses that directly inform drug discovery decisions.
• Design intelligent agentic workflows that streamline the deployment of innovative algorithms and computational models.
• Contribute to the evaluation and application of foundation models and virtual cell models to advance our understanding of disease biology.
• Collaborate closely with interdisciplinary and cross-functional teams, including biologists, chemists, data scientists, and other stakeholders.
• Lead and contribute to high-profile presentations and publications, ensuring effective communication of research findings and methodologies.
• Support the growth of the team by mentoring interns and junior scientists, sharing knowledge and fostering a collaborative research environment.

About You

• PhD completed by August 2026 in systems biology, computational biology, computer science, applied mathematics, or a related field with 0-3 years of relevant academic or industry experience.
• Experience in analyzing cellular multiomic data in academia or industry using Python.
• Hands-on experience building or deploying agentic analysis workflows.
• Record of productivity, innovation, and impact, demonstrated through publications or patents.
• Strong communication, organizational, interpersonal, and teamwork skills, with a successful history of collaboration across analytical disciplines.

Preferred

• Postdoctoral training experience.
• Familiarity with or interest in addressing challenges related to combinatorial synergy and tailored deployments of foundation and virtual cell models.

Why Choose Us

• Bring the miracles of science to life alongside a supportive, future-focused team.
• Discover endless opportunities to grow your talent and drive your career, whether its through a promotion or lateral move, at home or internationally.
• Enjoy a thoughtful, well-crafted rewards package that recognizes your contribution and amplifies your impact.
• Take good care of yourself and your family, with a wide range of health and wellbeing benefits including high-quality healthcare, prevention and wellness programs and at least 14 weeks gender-neutral parental leave.
• Be part of a pioneering biopharma company that engages patients early in drug development and uses their insights to design studies that reflect real-world needs.
• Help improve the lives of millions of people globally by making drug development quicker and more effective.
• Work at the forefront of drug discovery, harnessing cutting-edge AI, data, and digital platforms to push the boundaries of science.

Sanofi Inc. and its U.S. affiliates are Equal Opportunity and Aff…

All qualified applicants will receive consideration for employment without regard to race; color; creed; religion; national origin; age; ancestry; nationality; marital, domestic partnership or civil union status; sex, gender, gender identity or expression; affectional or sexual orientation; disability; veteran or military status or liability for military status; domestic violence victim status; atypical cellular or blood trait; genetic information (including the refusal to submit to genetic testing) or any other characteristic protected by law.

#GD-SA

#vhd

All compensation will be determined commensurate with demonstrated experience. Employees may be eligible to participate in Company employee benefit programs, and additional benefits information can be found here.