Senior Scientist, Proximity Assays & Antibody Technologies

Cell Signaling Technology, Inc.; Danvers (MA); On-site; USD 134,000 - 160,000; Full time

Benefits offered by this job

Medical and Dental plans (BCBS)

Vision Insurance

Life Insurance & Disability

401(k) Match

Tuition Reimbursement

Generous PTO

Pet Insurance

Employee Assistance Program

Free Parking

Job summary

Cell Signaling Technology (CST) is seeking an experienced scientist to collaborate with a dynamic team. You will drive research integrating CST antibodies with new technologies and develop assays using orthogonal approaches.

This onsite role emphasizes experimental design, data analysis, and clear scientific communication to guide product development and next steps. The position offers opportunities to work on single-cell analyses, DNA-conjugated antibody applications, and ongoing learning while

Qualifications

• Ph.D. degree in biological sciences; bench lab experience is required.
• Extensive PCR experience including nested and two-step PCR, melt curve analysis, primer design issues, troubleshooting.
• qPCR experience with dyes, TaqMan probes, normalization, and minimizing primer dimers.
• Experience with antibody pair assays, Western blot, and immunoprecipitation.
• Tissue culture experience including cell line maintenance, treatments, and lysis.
• Ability to independently test hypotheses, plan experiments, troubleshoot, and propose future ideas.
• Strong oral and written communication skills.

Responsibilities

• Design, develop, and optimize proximity assays using DNA-conjugated antibodies with high sensitivity readout.
• Perform experiments: Western blot, PCR/qPCR, flow cytometry, NGS, and cell culture.
• Analyze data, maintain records, and present findings with rationale for next steps.

Skills

PCR

qPCR

Western blotting

Immunoprecipitation

Tissue culture

Antibody assays

Single-cell analysis

Flow cytometry

Data analysis

Experimental design

Troubleshooting

Communication

Education

Ph.D. in biological sciences

Tools

MS Office

Google Docs

R

Python

Job description

Cell Signaling Technology (CST) is seeking an experienced scientist to collaborate with a dynamic team. You will drive research integrating CST antibodies with new technologies and develop assays using orthogonal approaches.

This onsite role emphasizes experimental design, data analysis, and clear scientific communication to guide product development and next steps. The position offers opportunities to work on single-cell analyses, DNA-conjugated antibody applications, and ongoing learning while